2023年

• 1.Yidan Zhu, Iwamoto T, Kajiwara T, Takahashi Y, Kochi M, Shien T, Taira N, Toyooka S, Doihara H：Predictive value of immune genomic signatures from breast cancer cohorts containing data for both response to neoadjuvant chemotherapy and prognosis after surgery. Breast Cancer 30(1) : 56-67, 2023
• 2.Kadowaki D, Noma K, Hashimoto M, Maeda N, TanabeS, Shirakawa Y, Fujiwara T：Case of robot-assisted salvage surgery for esophageal cancer with a mediastinal fistula after definitive chemoradiotherapy. Asian J Endosc Surg 16(3) : 505-509, 2023
• 3.Kuwada K, Kikuchi S, Kuroda S, Yoshida R, Takagi K, Noma K, Nishizaki M, Kagawa S, Umeda Y, Fujiwara T：Survival Impact of Postoperative Skeletal Muscle Loss in Gastric Cancer Patients Who Underwent Gastrectomy. Anticancer Research 43(1) : 223-230, 2023
• 4.Toshima T, Tanioka H, Mori Y, Tanaka T, Yasui K, Kimura K, Umeda Y, Fujiwara T, Nyuya A, Yano S, Nagasaka T：Genomically Stable Gastric Cancer Characterized by Hypomethylation in Wnt Signal Cascade. Oncology 101(2) : 105-116, 2023
• 5.Takagi K, Umeda Y, Yoshida R, Fuji T, Yasui K, Yagi T, Fujiwara T：Role of Surgery for Pancreatic Ductal Adenocarcinoma in the Era of Multidisciplinary Treatment. Journal of Clinical Medicine 12(2) : 465, 2023
• 6.Takagi K, Umeda Y, Yoshida R, Fuji T, Yasui K, Kimura J, Hata N, Yagi T, Fujiwara T：Surgical Techniques of Gastrojejunostomy in Robotic Pancreatoduodenectomy: Robot-Sewn versus Stapled Gastrojejunostomy Anastomosis. Journal of Clinical Medicine 12(2) : 732, 2023
• 7.Bram L J van den Broek, Maurice J W Zwart, Bert A Bonsing, Olivier R Busch, Jacob L van Dam, Ignace H J T de Hingh , Melissa E Hogg, Misha D Luyer, J S D Mieog, Luna A Stibbe, Kosei Takagi, T C K Tran, Roeland F de Wilde, Herbert J Zeh, Amer H Zureikat, Bas Groot Koerkamp, Marc G Besselink：Video Grading of Pancreatic Anastomoses During Robotic Pancreatoduodenectomy to Assess both Learning Curve and the Risk of Pancreatic Fistula - A Post Hoc Analysis of the LAELAPS-3 Training Program. Ann Surg 278(5) : e1048-e1054, 2023
• 8.Ishida M, Kuroda S, Choda Y, Otsuka S, Ueyama S, Tanaka N, Hato S, Kimura T, Muraoka A, Tanakaya K, Matsuda T, Takashima H, Nonaka Y, Ishii H, Shirakawa Y, Kamikawa Y, Fujiwara T：Incidence of Metachronous Remnant Gastric Cancer after Proximal Gastrectomy with the Double-flap Technique (rDFLAP-rGC Study): A Multicenter, Retrospective Study. Ann Surg Oncol 3302307-2316, 2023
• 9.Kakiuchi Y, Kuroda S, Kikuchi S, Kashima H, Nishizaki M, Kagawa S, Fujiwara T：Removing the Esophageal Stump During Reconstruction for Esophagojejunostomy in Total Gastrectomy for Gastric Cancer: the Modifed Overlap Method. Journal of Gastrointestinal Surgery 27643-645, 2023
• 10.Takata N, Kikuchi S, Kuroda S, Tanabe S, Maeda N, Noma K, Takahashi A, Umeda Y, Shikata K Ozaki K, Fujiwara T：ASO Visual Abstract: Effect of Patient-Participation Continuous Nutritional Counseling in Gastric Cancer Patients Who Underwent Gastrectomy. Ann Surg Oncol 30(2) : 1119, 2023
• 11.Kaibori M, Yoshii K, Umeda Y, Yagi T, Okabayashi T, Sui K, Mori A, Hamaguchi Y, Kajiyama K, Hokuto D, Monden K, Yoshizumi T, Nomura Y, Toriguchi K, Kim JM, Choi GH, Ryu JH, Koh Y, Kang KJ, You YK, Chun KS, Han YS, Cho CW, Choi YI, Kim DS, Yang JD, Mori K, Hiraoka A, Yamaue H, Nakamura M, Yamamoto M, Endo I：Surgical Outcomes of Laparoscopic versus Open Hepatectomy for Left Hepatocellular Carcinoma: Propensity Score Analyses Using Retrospective Japanese and Korean Individual Patient Data. Liver Cancer 12(1) : 32-43, 2023
• 12.Takahashi T, Kakiuchi Y, Kikuch S, Kuroda S, Takeda S, Shigeyasu K, Kondo Y, Teraishi F, Kagawa S, Fujiwara T：A Case Report of Non-typical Annular Pancreas Diagnosed during Laparoscopic Gastric Surgery. Acta Medica Okayama 77(1) : 91-95, 2023
• 13.Hata N, Shigeyasu K, Umeda Y, Yano S, Takeda S, Yoshida K, Fuji T, Yoshida R, Yasui K, Umeda H, Takahashi T, Kondo Y, Kishimoto H, Mori Y, Teraishi F, Yamamoto H, Michiue H, Nakamura K, Tazawa H, Fujiwara T：ADAR1 is a promising risk stratifcation biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer. Scientifc Reports 132078, 2023
• 14.Hata N, Shigeyasu K, Umeda Y, Yano S, Takeda S, Yoshida K, Fuji T, Yoshida R, Yasui K, Umeda H, Takahashi T, Kondo Y, Kishimoto H, Mori Y, Teraishi F, Yamamoto H, Michiue H, Nakamura K, Tazawa H, Fujiwara T：ADAR1 is a promising risk stratification biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer. Sci Rep 13(1) : 2078, 2023
• 15.Takagi K, Umeda Y, Yoshida R, Fuji T, Yasui K, Yagi T, Fujiwara T：Robotic surgery for congenital biliary dilatation using the scope switch technique (with video). Asian Journal of Surgery 46(10) : 4399-4402, 2023
• 16.Takagi K, Hata N, Kimura J, Kikuchi S, Noma K, Yasui K, Fuji T, Yoshida R,Umeda Y, Yagi T, Fujiwara T：Impact of educational video on performance in robotic simulation training (TAKUMI-1): a randomized controlled trial. Journal of Robotic Surgery 17(4) : 1547-1553, 2023
• 17.Takagi K, Umeda Y, Yoshida R, Fuji T, Yasui K, Kimura J, Hata N, Yagi T, Fujiwara T：Role of the Pfannenstiel Incision in Robotic Hepato-Pancreato-Biliary Surgery. J. Clin. Med 12(5) : 1971, 2023
• 18.Takagi K, Noma K, Nagai Y, Kikuchi S, Umeda Y, Yoshida R, Fuji T, Yasui K, Tanaka T, Kashima H, Yagi T, Fujiwara T：Impact of cancer-associated fibroblasts on survival of patients with ampullary carcinoma. Front. Oncol. 131072106, 2023
• 19.Nakamura K, Shigeyasu K, Okamoto K, Matsuoka H, Masuyama H：ADAR1 has an oncogenic function and can be a prognostic factor in cervical cancer. Scientific reports 13(1) : 4720, 2023
• 20.Ikeda T, Noma K, Okura K, Katayama S, Takahashi Y, Maeda N, Tanabe S, Wakita A, Hamada M, Fujiwara T, Senda M：Validity of the 30-Second Chair-Stand Test to Assess Exercise Tolerance and Clinical Outcomes in Patients with Esophageal Cancer: A Retrospective Study with Reference to 6-Minute Walk Test Results. Acta Medica Okayama 77(2) : 193-197, 2023
• 21.Ishida M, Kuroda S, Choda Y, Otsuka S, Ueyama S, Tanaka N, Hato S, Kimura T, Muraoka A, Tanakaya K, Matsuda T, Takashima H, Nonaka Y, Ishii H, Shirakawa Y, Kamikawa Y, Fujiwara T：ASO Visual Abstract: Incidence of Metachronous Remnant Gastric Cancer After Proximal Gastrectomy with the Double-Flap Technique (rD-FLAP-rGC Study): A Multicenter Retrospective Study. Ann Surg Oncol 30(4) : 2317-2318, 2023
• 22.Sakamoto M, Teraishi F, Shigeyasu K, Kagawa S, Fujiwara T：Locally Advanced Rectal Cancer Invading the Gluteus Maximus Muscle Completely Responded to Total Neoadjuvant Therapy. Acta Medica Okayama 77(2) : 209-213, 2023
• 23.Washio K, Tamefusa K, Ochi M, Kanamitsu K, Ishida H, Fujiwara K, Nishida K, Tamai K, Washio Y, Yoshimoto J, Noda T, Tsukahara H： Three Cases of Down Syndrome with Transient Abnormal Myelopoiesis who Underwent Liver Biopsy before Induction of Low-Dose Cytarabine. Acta Medica Okayama 77(2) : 215-220, 2023
• 24.Kashima H, Kikuchi S, Kuroda S, Fujiwara T：Laparoscopic and Endoscopic Cooperative Surgery for Gastric Submucosal Tumor Near Esophagogastric Junction With Sliding Hiatal Hernia. Cureus 15(4) : e37902, 2023
• 25.Takahashi K, Shigeyasu K, Kondo Y, Gotoh K, Yano S, Umeda Y, Inokuchi T, Xu C, Yoshida K, Umeda H, Takahashi T, Takeda S, Yoshida R, Teraishi F, Kishimoto H, Mori Y, Noma K, Okugawa Y, Hiraoka S, Michiue H, Tazawa H, Matsushita O, Goel A, Fujiwara T：RNA Editing is a Valuable Biomarker for Predicting Carcinogenesis in Ulcerative Colitis. Journal of Crohn's and Colitis 17(5) : 754-766, 2023
• 26.Berend Robert Beumer, Takagi K, Stefan Buettner, Umeda Y, Yagi T, Fujiwara T, Jeroen Laurens Ad van Vugt, Jan Nicolas Maria IJzermans：Impact of sarcopenia on clinical outcomes for patients with resected hepatocellular carcinoma: A retrospective comparison of eastern and western cohorts. Int J Surg. 109(8) : 2258-2266, 2023
• 27.Kondo Y, Fujiwara T：Laparoscopic Surgical Options as a Minimally Invasive Procedure for a Patient With Recurrent Postoperative Pain in Anterior Cutaneous Nerve Entrapment Syndrome: A Case Report. Cureus 15(5) : e39366, 2023
• 28.Iwamuro M,Tanaka T, Kagawa S, Inoo S, Otsuka M：Collagenous Colitis in a Patient With Gastric Cancer Who Underwent Chemotherapy. Cureus 15(5) : e39466, 2023
• 29.Komoto S, Noma K, Kato T, Kobayashi T, Nishiwaki N, Narusaka T, Sato H,Katsura Y, Kashima H, Kikuchi S, Ohara T, Tazawa H, Fujiwara T：Conventional Cancer Therapies Can Accelerate Malignant Potential of Cancer Cells by Activating Cancer-Associated Fibroblasts in Esophageal Cancer Models. Cancers (Basel) 15(11) : 2971, 2023
• 30.Kanaya N, Kitamura Y, Lopez Vazquez M, Franco A, Chen KS, van Schaik TA,Farzani TA, Borges P, Ichinose T, Seddiq W, Kuroda S, Boland G, Jahan N, Fisher D, Wakimoto H, Shah K：Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas. Sci Transl Med 15(698) : eade8732, 2023
• 31.Sonoi M, Noma K, Tanabe S, Maeda N, Shirakawa Y, Morimatsu H：Assessing the Role of Perioperative Nutritional Education in Improving Oral Intake after Oesophagectomy: A Retrospective Study. Asian Pac J Cancer Prev 24(6) : 2037-2041, 2023
• 32.Ito Y, Hamaguchi T, Takashima A, Mizusawa J, Shimada Y,Shiozawa M, Mizoguchi N, Kodaira T, Komori K, Ohue M, Konishi K, Teraishi F, Kinouchi M, Murata K, Fujita F, Watanabe M, Iinuma G, Ishida F, Saida Y, Matsuda T, Katayama H, Fukuda H, Kanemitsu Y：Definitive S-1/mitomycin-C chemoradiotherapy for stage II/III anal canal squamous cell carcinoma: a phase I/II dose-finding and single-arm confirmatory study (JCOG0903). Int J Clin Oncol 28(8) : 1063-1072, 2023
• 33.Fischer AD, Veronese Paniagua DA, Swaminathan S, Kashima H, Rubin DC, Madison BB：The oncogenic function of PLAGL2 is mediated via ASCL2 and IGF2 and a Wnt-independent mechanism in colorectal cancer. Am J Physiol Gastrointest Liver Physiol 325(2) : G196-G211, 2023
• 34.Matsumoto T, Noma K, Maeda N, Kato T, Moriwake K, Kawasaki K, Hashimoto M, Tanabe S, Shirakawa Y, Fujiwara T：Safe and curative modified two-stage operation for T4 esophageal cancer after definitive chemoradiotherapy: a case report. Surgical Case Reports 99(1) : 119, 2023
• 35.Kimura J, Sui K, Tabuchi M, Sakamoto S, Murokawa T, Iwata J, Morita S, Iiyama T, Okabayashi T：Preoperative percent body fat in bioelectrical impedance analysis predicts pancreatic fistula after pancreaticoduodenectomy. Langenbecks Arch Surg 408(1) : 248, 2023
• 36.Nishiwaki N, Noma K, Ohara T, Kunitomo T, Kawasaki K, Akai M, Kobayashi T, Narusaka T, Kashima H, Sato H, Komoto S, Kato T, Maeda N, Kikuchi S, Tanabe S, Tazawa H, Shirakawa Y, Fujiwara T：Overcoming cancer-associated fibroblast-induced immunosuppression by anti-interleukin-6 receptor antibody. Cancer Immunol Immunother 72(7) : 2029-2044, 2023
• 37.Ihara H, Yoshio K, Tanabe S, Sugiyama S, Hashimoto M, Maeda N, Akagi S, Takao S, Noma K, Hiraki T：Outcomes of solitary postoperative recurrence of esophageal squamous cell carcinoma diagnosed with FDG-PET/CT and treated with definitive radiation therapy. Esophagus 20(3) : 548-556, 2023
• 38.Hanzawa S, Teraishi F, Matsumi Y, Tachibana K, Fujiwara T：Precision laparoscopic sentinel node navigation surgery for femoral skin cancer. Asian J Endosc Surg 16(3) : 523-527, 2023
• 39.Sakurai A, Uka A, Iguchi T, Tomita K, Matsui Y, Kakiuchi Y, Kuroda S, Fujiwara T, Hiraki T：Omental Abscess after Laparoscopic Proximal Gastrectomy Successfully Treated with Percutaneous Drainage. Acta Medica Okayama 77(6) : 665-669, 2023
• 40.Moleirinho S, Kitamura Y, Borges PSGN, Auduong S, Kilic S, Deng D, Kanaya N, Kozono D, Zhou J, Gray JJ, Revai-Lechtich E, Zhu Y, Shah K：Fate and Efficacy of Engineered Allogeneic Stem Cells Targeting Cell Death and Proliferation Pathways in Primary and Brain Metastatic Lung Cancer. Stem Cells Transl Med 12(7) : 444-458, 2023
• 41.Takagi K, Umeda Y, Yoshida R, Fuji T, Yasui K, Yagi T, Fujiwara T ：Innovative suture technique for robotic hepaticojejunostomy: double-layer interrupted sutures. Langenbeck's Archives of Surgery 408(1) : 284, 2023
• 42.Nogi S, Noma N, Hashimoto M, Kato T, Maeda N, Tanabe S, Shirakawa T, Fujiwara T ：Adenocarcinoma arising from widespread heterotopic gastric mucosa in the cervicothoracic esophagus: a case report. Surgical Case Reports 9(11) : 132, 2023
• 43.Yoshimoto M, Kagawa S, Kajioka H, Taniguchi A, Kuroda S, Kikuchi S, Kakiuchi Y, Yagi T, Nogi S, Teraishi F, Shigeyasu K, Yoshida R, Umeda Y, Noma K, Tazawa H, Fujiwara T：Dual antiplatelet therapy inhibits neutrophil extracellular traps to reduce liver micrometastases of intrahepatic cholangiocarcinoma. Cancer Lett 567216260, 2023
• 44.Kawasaki K, Noma K, Kato T, Ohara T, Tanabe S, Takeda Y, Matsumoto H, Nishimura S, Kunitomo T, Akai M, Kobayashi T, Nishiwaki N, Kashima H, Maeda N, Kikuchi S, Tazawa H, Shirakawa Y, Fujiwara T：PD‑L1‑expressing cancer‑associated fbroblasts induce tumor immunosuppression and contribute to poor clinical outcome in esophageal cancer in esophageal cancer. Cancer Immunology, Immunotherapy 723787–3802, 2023
• 45.Takagi K, Umeda Y, Fuji T, Yasui K, Fujiwara T：Robotic Pancreaticoduodenectomy Using the Right Posterior Superior Mesenteric Artery Approach. J Gastrointest Surg 3069-3070, 2023
• 46.Moriwake K, Isozaki H, Takama T, Murakami S, Matsumoto S：A case report of splenic injury related to colonoscopy: Fortunately treated with conservative treatment. DEN Open 4(1) : e287, 2023
• 47.Kawasaki K, Noma K, Kato T, Ohara T, Tanabe S, Takeda Y, Matsumoto H, Nishimura S, Kunitomo T, Akai M, Kobayashi T, Nishiwaki N, Kashima H, Maeda N, Kikuchi S, Tazawa H, Shirakawa Y, Fujiwara T：PD-L1-expressing cancer-associated fibroblasts induce tumor immunosuppression and contribute to poor clinical outcome in esophageal cancer. Cancer Immunol Immunother 72(11) : 3787-3802, 2023
• 48.Kakiuchi Y, Kuroda S, Choda Y, Otsuka S, Ueyama S, Tanaka N, Muraoka A, Hato S, Kamikawa Y, Fujiwara T：Prognostic nutritional index is a prognostic factor for patients with gastric cancer and esophagogastric junction cancer undergoing proximal gastrectomy with esophagogastrostomy by the double-flap technique: A secondary analysis of the rD-FLAP study. Surgical Oncology 50101990, 2023
• 49.Kakiuchi Y, Kuroda S, Kanaya N, Kagawa S, Tazawa H, Fujiwara T：Exosomes as a drug delivery tool for cancer therapy: a new era for existing drugs and oncolytic viruses. Expert Opinion on Therapeutic Targets 27807-816, 2023
• 50.Hikasa Y, Suzuki S, Tanabe S, Noma K, Shirakawa Y, Fujiwara T, Morimatsu H：Stroke volume variation and dynamic arterial elastance predict fuid responsiveness even in thoracoscopic esophagectomy: a prospective observational study. Journal of Anesthesia 37(6) : 930-937, 2023
• 51.Hori N, Tazawa H, Li Y, Okura T, Kikuchi S, Kuroda S, Ohara T, Noma K, Nishizaki M, Urata Y, Kagawa S, Fujiwara T：Intraperitoneal Administration of p53-armed Oncolytic Adenovirus Inhibits Peritoneal Metastasis of Diffuse-type Gastric Cancer Cells. ANTICANCER RESEARCH 43(11) : 4809-4821, 2023
• 52.Teraishi F, Shigeyasu K, Kondo Y, Kagawa S, Tamura R, Matsuoka Y, Morimatsu H, Fujiwara T：Clinical Impact of Prehabilitation on Elective Laparoscopic Surgery in Frail Octogenarians With Colorectal Cancer. Anticancer Research 435597-5604, 2023
• 53.Tamura S, Tazawa H, Hori N, Li Y, Yamada M, Kikuchi S, Kuroda S, Urata Y, Kagawa S, Fujiwara T：p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells. PLoS One 18(11) : e0294491, 2023
• 54.Takagi K, Fuji T, Yamada M, Kimura J, Yasui K, Umeda Y, Fujiwara T：Robotic Pancreatoduodenectomy in Portal Annular Pancreas Using a Hanging Maneuver with Indocyanine Green Fluorescence Imaging. Ann Surg Oncol 311933-1936, 2023
• 55.Takagi K, Fuji T, Yasui K, Umeda Y, Fujiwara T：ASO Author Reflections: The Role of Robotic Surgery in Patients with Portal Annular Pancreas. Annals of Surgical Oncology 311943, 2023

2022年

• 1.Umeda Y，Nagasaka T，Takagi K，Yoshida R，Yoshida K，Fuji T，Matsuda T，Yasui K，Kumano K，Sato H，Yagi T，Fujiwara T：Technique of vessel-skeletonized parenchyma-sparing hepatectomy for the oncological treatment of bilobar colorectal liver metastases．Langenbecks Arch Surg 407(2)：685-697，2022
• 2.Ikeda T，Noma K，Maeda N，Tanabe S，Sakamoto Y，Katayama Y，Shirakawa Y，Fujiwara T，Senda M：Effectiveness of early exercise on reducing skeletal muscle loss during preoperative neoadjuvant chemotherapy for esophageal cancer．Surg Today 52(8)：1143-1152，2022
• 3.Nakagawa K，Sho M，Okada K，Akahori T，Aoyama T，Eguchi H，Fujii T，Higuchi R，Kanaji S，Kanetaka K，Kuroda S，Nagakawa Y，Nunobe S，Yamada S，Yamashita H，Yamaue H，Kodera Y：Surgical results of non-ampullary duodenal cancer: a nationwide survey in Japan．J Gastroenterol 57(2)：70-81，2022
• 4.Kanaya N，Kuroda S，Kakiuchi Y，Takeda S，Kikuchi S，Noma K，Yoshida R，Umeda Y，Teraishi F，Nishizaki M，Kagawa S，Fujiwara T：Surgical technique of suprapancreatic D2 lymphadenectomy focusing on the posterior hepatic plexus for advanced gastric cancer．Langenbecks Arch Surg 407(2)：871-877，2022
• 5.Yamanaka-Kohno R，Shirakawa Y，Yokoi A，Inoue-Minakuchi M，Kobayashi M，Noma K，Morita M，Kuboki T，Morimatsu H，Soga Y：Patients scheduled to undergo esophageal surgery should have the highest priority for perioperative oral management triage: a cross-sectional study．Gen Thorac Cardiovasc Surg 70(4)：378-385，2022
• 6.Umeda Y，Mitsuhashi T，Kojima T，Satoh D，Sui K，Endo Y，Inagaki M，Oishi M，Yagi T，Fujiwara T：Impact of lymph node dissection on clinical outcomes of intrahepatic cholangiocarcinoma: Inverse probability of treatment weighting with survival analysis．J Hepatobiliary Pancreat Sci 29(2)：217-229，2022
• 7.Hamada K，Kawahara Y，Tanimoto T，Ohto A，Toda A，Aida T，Yamasaki Y，Gotoda T，Ogawa T，Abe M，Okanoue S，Takei K，Kikuchi S，Kuroda S，Fujiwara T，Okada H：Application of convolutional neural networks for evaluating the depth of invasion of early gastric cancer based on endoscopic images．J Gastroenterol Hepatol 37(2)：352-357，2022
• 8.Matsumoto K，Ohara T，Fujisawa M，Takaki A，Takahara M，Kato H，Yoshida R，Umeda Y，Yagi T，Matsukawa A，Okada H：Diagnostic Utility of the PD-L1 Immunostaining in Biopsy Specimens of Patients with Biliary Tract Neoplasms．J Gastrointest Surg 26(6)：1213-1223，2022
• 9.Itamoto K，Kumamaru H，Aikou S，Yagi K，Yamashita H，Nomura S，Miyata H，Kuroda S，Fujiwara T，Endo S，Kitagawa Y，Kakeji Y，Seto Y：No association between hospital volume and short-term outcomes of some common surgeries: a　retrospective cohort study based on a Japanese nationwide database．Surg Today 52(6)：941-952，2022
• 10.Kajiwara Y，Iwamoto T，Zhua Y，Kochi M，Shien T，Taira N，Doihara H，Toyooka S：Gene Expression Profiling between Patient Groups with High and Low Ki67 Levels after Short-term Preoperative Aromatase Inhibitor Treatment for Breast Cancer．Acta Med Okayama 76(4)：399-408，2022
• 11.Takagi K，Nagai Y，Umeda Y，Yoshida R，Yoshida K，Fuji T，Kumano K，Yasui K，Yagi T，Fujiwara T：Prognostic Value of the Regional Lymph Node Station in Pancreatoduodenectomy for Ampullary Carcinoma．In Vivo 36(2)：973-978，2022
• 12.Masuda T，Tazawa H，Hashimoto Y，Ieda T，Kikuchi S，Kuroda S，Noma K，Urata Y，Kagawa S，Fujiwara T：Overexpression of adenovirus E1A reverses transforming growth factor-β-induced epithelial-mesenchymal transition in human esophageal cancer cells．Acta Medica Okayama 76(2)：203-215，2022
• 13.Hamada K，Kanzaki H，Miyahara K，Nakagawa M，Mouri H，Mizuno M，Takahashi S，Hori S，Nasu J，Tsuzuki T，Miyaike J，Takenaka R，Yamauchi K，Kobayashi S，Toyokawa T，Inoue M，Nishimura M，Matsubara M，Tomoda J，Yamasaki Y，Tanaka T，Shirakawa Y，Kawahara Y，Fujiwara T，Okada H：Clinicopathological characteristics of superficial Barrett's adenocarcinoma in a Japanese Population: a retrospective, multicenter study．Intern Med 61(8)：1115-1123，2022
• 14.Takagi K，Umeda Y，Yoshida R，Yoshida K，Fuji T，Kumano K，Yasui K，Yagi T，Fujiwara T：Prognostic Value of the Regional Lymph Node Station in Pancreatic Neuroendocrine Tumor．Anticancer Res 42(5)：2797-2801，2022
• 15.Sato H，Yoshida R，Yasui K，Umeda Y，Yoshida K，Fuji T，Kumano K，Takagi K，Yagi T，Fujiwara T：Feasibility of local therapy for recurrent pancreatic cancer．Pancreatology 22(6)：774-781，2022
• 16.Konishi D，Umeda Y，Yoshida K，Shigeyasu K，Yano S，Toji T，Takeda S，Yoshida R，Yasui K，Fuji T，Matsumoto K，Kishimoto H，Michiue H，Teraishi F，Kato H，Tazawa H，Yanai H，Yagi T，Goel A，Fujiwara T：Regulatory T cells induce a suppressive immune milieu and promote lymph node metastasis in intrahepatic cholangiocarcinoma．Br J Cancer 127(4)：757-765，2022
• 17.Kikuchi S，Takata N，Kuroda S，Umeda H，Tanabe S，Maeda N，Takagi K，Noma K，Hasegawa Y，Nawachi K，Kagawa S，Umeda Y，Shikata K，Fujiwara T：Impact of Amino Acids Nutrition Following Gastrectomy in Gastric Cancer Patients．Anticancer Res 42(7)：3637-3643，2022
• 18.Fuji T，Umeda Y，Takagi K，Yoshida R，Yoshida K，Yasui K，Matsumoto K，Kato H，Yagi T，Fujiwara T：Optimal surveillance of intraductal papillary mucinous neoplasms of the pancreas focusing on remnant pancreas recurrence after surgical resection．BMC Cancer 22(1)：588，2022
• 19.Ogawa T，Kikuchi S，Tabuchi M，Mitsui E，Une Y，Tazawa H，Kuroda S，Noma K，Ohara T，Kagawa S，Urata Y，Fujiwara T：Modulation of p53 expression in cancer-associated fibroblasts prevents peritoneal metastasis of gastric cancer．Mol Ther Oncolytics 25：249-261，2022
• 20.Takagi K，Kumano K，Umeda Y，Yoshida R，Fuji T，Yasui K，Yagi T，Fujiwara T：Surgical Strategies to Approaching the Splenic Artery in Robotic Distal Pancreatectomy．Anticancer Res 42(9)：4471-4476，2022
• 21.Nishiwaki N，Noma K，Kunitomo T，Hashimoto M，Maeda N，Tanabe S，Sakurama K，Shirakawa Y，Fujiwara T：Neoadjuvant chemotherapy for locally advanced esophageal cancer comparing cisplatin and 5-fluorouracil versus docetaxel plus cisplatin and 5-fluorouracil: a propensity score matching analysis．Esophagus 19(4)：626-638，2022
• 22.Ito T，Takashima A，Yamazaki K，Yukami H，Uetake H，Tsuda M，Suto T，Moriwaki T，Sugimoto N，Ojima H，Takii Y，Yasui H，Esaki T，Tsuji A，Goto M，Saruta M，Otsu S，Shinozaki K，Denda T，Ueno H，Nagashima K，Shimada Y：Primary tumor location as a predictor of survival in patients with RAS wild-type colorectal cancer who receive molecularly targeted drugs as first-line therapy: a multicenter real-world observational study by the Japanese Society for Cancer of the Colon a．Int J Clin Oncol 27(9)：1450-1458，2022
• 23.Komatsu Y，Shigeyasu K，Yano S，Takeda S，Takahashi K，Hata N，Umeda H，Yoshida K，Mori Y，Yasui K，Yoshida R，Kondo Y，Kishimoto H，Teraishi F，Umeda Y，Kagawa S，Michiue H，Tazawa H，Goel A，Fujiwara T：RNA editing facilitates the enhanced production of neoantigens during the simultaneous administration of oxaliplatin and radiotherapy in colorectal cancer．Scientific Reports 12(1)：13540，2022
• 24.Kunisawa S，Ishida H，Ikai H，Nagano H，Fujiwara T，Ohdan H，Fujiwara Y，Tajima Y，Ueno T，Fujiwara Y，Shimada M，Suzuki Y，Watanabe Y，Hanazaki K，Kakeji Y，Kumamaru H，Takahashi A，Miyata H，Imanaka Y：Impact of the hospital volume and setting on postoperative complications of surgery for gastroenterological cancers in a regional area of Western Japan．Surg Today 53(2)：214-222，2022
• 25.Takagi K，Murotani K，Kamoshita S，Kuroda A：Dose-Dependent Effects of Amino Acids on Clinical Outcomes in Adult Medical Inpatients Receiving Only Parenteral Nutrition: A Retrospective Cohort Study Using a Japanese Medical Claims Database．Nutrients 14(17)：3541，2022
• 26.Kakiuchi Y，Kuroda S，Kikuchi S，Kagawa S，Fujiwara T：Prognostic risk factors for postoperative long-term outcomes in elderly stage IA gastric cancer patients．J Gastrointest Oncol 13(5)：2178-2185，2022
• 27.Araki H，Tazawa H，Kanaya N，Kajiwara Y，Yamada M，Hashimoto M，Kikuchi S，Kuroda S，Yoshida R，Umeda Y，Urata Y，Kagawa S，Fujiwara T：Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer．Mol Ther Oncolytics 27：3-13，2022
• 28.Takata N，Kikuchi S，Kuroda S，Tanabe S，Maeda N，Noma K，Takahashi A，Umeda Y，Shikata K，Ozaki K，Fujiwara T：Effect of Patient-Participation Continuous Nutritional Counseling in Gastric Cancer Patients who Underwent Gastrectomy．Ann Surg Oncol 30(2)：1110-1118，2022
• 29.Komatsu Y，Shigeyasu K，Takeda S，Mori Y，Takahashi K，Hata N，Miyamoto K，Umeda H，Kakiuchi Y，Kikuchi S，Yano S，Kuroda S，Kondo Y，Kishimoto H，Teraishi F，Nishizaki M，Kagawa S，Fujiwara T：Association Between Advanced T Stage and Thick Rectus Abdominis Muscle and Outlet Obstruction and High-Output Stoma After Ileostomy in Patients With Rectal Cancer．Int Surg 106(3)：102-111，2022
• 30.Gohara S，Shinohara K，Yoshida R，Kariya R，Tazawa H，Hashimoto M，Inoue J，Kubo R，Nakashima H，Arita H，Kawaguchi S，Yamana K，Nagao Y，Iwamoto A，Sakata J，Matsuoka Y，Takeshita H，Hirayama M，Kawahara K，Nagata M，Hirosue A，Kuwahara Y，Fukumoto M， Okada S，Urata Y，Fujiwara T，Nakayama H：An oncolytic virus as a promising candidate for the treatment of radioresistant oral squamous cell carcinoma．Mol Ther Oncolytics 27：141-156，2022
• 31.Takagi K，Murotani K，Kamoshita S，Kuroda A：Clinical impact of lipid injectable emulsion in internal medicine inpatients exclusively receiving parenteral nutrition: a propensity score matching analysis from a Japanese medical claims database．BMC Med 20(1)：371，2022
• 32.Okabayashi T，Sui K，Tabuchi M，Murokawa T，Sakamoto S，Iwata J，Morita S，Okamoto N，Iiyama T，Shimada Y，Fujiwara T：Possibility of Neoadjuvant Treatment for Radiologically Judged Resectable Pancreatic Cancer．J Clin Med 11(22)：6792-，2022
• 33.Kajiwara Y，Tazawa H，Yamada M，Kanaya N，Fushimi T，Kikuchi S，Kuroda S，Ohara T，Noma K，Yoshida R，Umeda Y，Urata Y，Kagawa S，Fujiwara T：Oncolytic virus-mediated reducing of myeloid-derived suppressor cells enhances the efficacy of PD-L1 blockade in gemcitabine-resistant pancreatic cancer．Cancer Immunology, Immunotherapy：doi: 10.1007/s00262-022-03334-x.，2022
• 34.Sato H，Noma K，Ohara T，Kawasaki K，Akai M，Kobayashi T，Nishiwaki N，Narusaka T，Komoto S，Kashima H，Katsura Y，Kato T，Kikuchi S，Tazawa H，Kagawa S，Shirakawa Y，Kobayashi H，Fujiwara T：Dual-targeted near-infrared photoimmunotherapy for esophageal cancer and cancer-associated fibroblasts in the tumor microenvironment．Scientific Reports 12(1)：20152，2022
• 35.Takagi K，Umeda Y，Yoshida R，Fuji T，Yasui K，Kimura J，Hata N，Mishima K，Yagi T，Fujiwara T：Surgical Strategies to Dissect around the Superior Mesenteric Artery in Robotic Pancreatoduodenectomy．J Clin Med 11(23)：7112，2022
• 36.Kakiuchi Y，Kikuchi S，Kuroda S，Kagawa S，Fujiwara T：Involvement in the tumor-infiltrating CD8+ T cell expression by the initial disease of remnant gastric cancer．World J Surg Oncol 20(1)：374，2022
• 37.Futagami H，Sato H，Yoshida R，Yasui K，Yagi T，Fujiwara T：Acute acalculous cholecystitis caused by SARS-CoV-2 infection: A case report and literature review．Int J Surg Case Rep 90：106731，2022
• 38.Tamaki A，Tani Y，Sato H，Yoshida R，Yasui K，Horiguchi S，Kuise T，Umeda Y，Yoshida K，Fuji T，Kumano K，Takagi K，Yagi T，Fujiwara T：Surgical resection of mixed neuroendocrine-non-neuroendocrine neoplasm in the biliary system: a report of two cases．Surg Case Rep 8(1)：38，2022
• 39.Takagi K，Umeda Y，Yoshida R，Yagi T，Fujiwara T：The Gastrohepatic Ligament Approach in Robotic Spleen-Preserving Distal Pancreatectomy with Resection of the Splenic Vessels: The Superior Window Approach in the Warshaw Technique．J Gastrointest Surg 26(6)：1342-1344，2022
• 40.Takagi K，Yoshida R，Umeda Y，Yagi T：Division of the pancreas at the right side of the superior mesenteric vein in robotic distal pancreatectomy: The splenic vessel-first approach．Asian J Surg 45(8)：1591-1593，2022
• 41.Teraishi F，Jikuhara A，Ogawa R，Fujiwara T：Descending colon cancer coincident with schistosoma japonicum in an 89-year-old male．Acta Med Okayama 76(33)：355-358，2022
• 42.Kagoura M，Takagi K，Yoshida K，Yoshida R，Umeda Y，Yagi T，Fujiwara T：Gastrointestinal: Intraductal papillary-mucinous carcinoma of the pancreas originating in the Santorini duct．J Gastroenterol Hepatol 37(12)：2204, 2022
• 43.Teraishi F，Shigeyasu K，Kagawa S，Fujiwara T：Anorectal leiomyoma with GLUT1 overexpression mimicking malignancy on FDG-PET/CT．J Surg Case Rep 2022(5)：rjac101，2022
• 44.Kawabe K，Sato H，Kitano A，Yoshida R，Yasui K，Umeda Y，Yoshida K，Fuji T，Kumano K，Takagi K，Kagoura M，Yagi T，Fujiwara T：Adenomatoid mesothelioma arising from the diaphragm: a case report and review of the literature．J Med Case Rep 16(1)：228，2022
• 45.Tani Y，Sato H，oshida R，Yasui K，Umeda Y，Yoshida K，Fuji T，Kumano K，Takagi K，Kagoura M，Yagi T，Fujiwara T：Favorable control of hepatocellular carcinoma with peritoneal dissemination by surgical resection using indocyanine green fluorescence imaging: a case report and review of the literature．J Med Case Rep 16(1)：222，2022
• 46.Watanabe T，Matsumoto H，Yoshida R，Yasui K，Yagi T，Kimata Y：Pectoralis Major and Serratus Anterior Muscle Flap for Diaphragmatic Reconstruction．Ann Thorac Surg 114(1)：e51-e54，2022
• 47.Hashimoto M，Shirakawa Y，Tanabe S，Tanaka T，Maeda N，Sakurama K，Noma K，Fujiwara T：Verrucous carcinoma of the esophagus with complete response after chemoradiotherapy．Surg Case Rep 8(1)：128，2022
• 48.Tanimoto T，Noda T，Imaji R，Nouso H：A case of esophageal atresia with the bronchial-like lower esophagus which originates from the left lower lobe bronchus．Surg Case Rep 8(1)：156，2022
• 49.Takagi K，Yoshida R，Umeda Y，Fuji T，Yasui K，Yagi T，Fujiwara T：Robotic Spleen-Preserving Distal Pancreatectomy with Preservation of Splenic Vessels Using the Gastrohepatic Ligament Approach: The Superior Window Approach in the Kimura Technique．Dig Surg 39 (4)：137-140，2022
• 50.Teraishi F，Jikuhara A，Ogawa R，Fujiwara T：Surgical Resection for Local and Lateral Lymph Node Recurrence of MSI-high Cecal Cancer with the BRAF V600E Mutation．Acta Medica Okayama 76(5)：605-608，2022
• 51.Takagi K，Hata N，Fujii Y：A rare cause of afferent loop syndrome．Gastro Hep Advances：https://doi.org/10.1016/j.gastha.2022.10.009，2022
• 52.Takagi K，Umeda Y，Kimura J，Yagi T：Robotic liver resection for hepatic cyst using indocyanine green fluorescence imaging．Asian J Surg ：doi: 10.1016/j.asjsur.2022.10.059.，2022
• 53.Tsuge M，Kodera A，Sumitomo H，Araki T，Yoshida R，Yasui K，Sato H，Washio Y，Washio K，Shigehara K，Yashiro M，Yagi T，Tsukahara H：Neonatal hemochromatosis with epsilon gamma delta beta-thalassemia: a case report and analysis of serum iron regulators．BMC Pediatrics 22(1)：622，2022
• 54.Hanzawa S, Teraishi F, Matsumi Y, Tachibana K, Fujiwara T：Precision laparoscopic sentinel node navigation surgeryfor femoral skin cancer．Asian J Endosc Surg：doi: 10.1111/ases.13159.，2022
• 55.Takagi K，Umeda Y，Yoshida R，Yagi T，Fujiwara T：A Systematic Review of Minimally Invasive Versus Open Radical Antegrade Modular Pancreatosplenectomy for Pancreatic Cancer．Anticancer Research 42(2)：653-660，2022
• 56.Tazawa H，Shigeyasu K，Noma K，Kagawa S，Sakurai F，Mizuguchi H，Kobayashi H，Imamura T，Fujiwara T：Tumor-targeted fluorescence labeling systems for cancer diagnosis and treatment．Cancer Science 113(6)：1919-1929，2022
• 57.Takagi K，Umeda Y，Yoshida R，Fuji T，Yasui K，Yagi T，Fujiwara T：Current status and future perspectives of minimally invasive and open radical antegrade modular pancreatosplenectomy for pancreatic ductal adenocarcinoma: a review．Laparosc Surg 6：39，2022
• 58.Nakagawa K，Sho M，Fujishiro M，Kakushima N，Horimatsu T，Okada K，Iguchi M，Uraoka T，Kato M，Yamamoto Y，Aoyama T，Akahori T，Eguchi H，Kanaji S，Kanetaka K，Kuroda S，Nagakawa Y，Nunobe S，Higuchi R，Fujii T，Yamashita H，Yamada S，Narita Y，Honma Y，Muro K，Ushiku T，Ejima Y，Yamaue H，Kodera Y：Clinical practice guidelines for duodenal cancer 2021．J Gastroenterol 57(12)：927-941，2022

2021年

• 1.Kajioka H, Kagawa S, Ito A, Yoshimoto M, Sakamoto S, Kikuchi S, Kuroda S, Yoshida R, Umeda Y, Noma K, Tazawa H, Fujiwara T : Targeting neutrophil extracellular traps with thrombomodulin prevents pancreatic cancer metastasis. Cancer Lett , 497:1-13 , 2021
• 2.Sui K, Okabayashi T, Umeda Y, Oishi M, Kojima T, Sato D, Endo Y, Ota T, Hioki K, Inagaki M, Matsuda T, Hirai R, Kimura M, Yagi T, Fujiwara T : Prognostic Utility of the Glasgow Prognostic Score for the Long-Term Outcomes After Liver Resection for Intrahepatic Cholangiocarcinoma: A Multi-institutional Study. World J Surg , 45(1) : 279-290,2021
• 3.Yamanaka-Kohno R, Shirakawa Y, Inoue-Minakuchi M, Yokoi A, Muro M, Kosaki H, Tanabe S, Fujiwara T, Morita M : Association of dental occlusal support with the Prognostic Nutritional Index in patients with esophageal cancer who underwent esophagectomy. Esophagus , 18(1) : 49-55 , 2021
• 4.Shirakawa Y, Noma K, Maeda N, Tanabe S, Sakurama K, Fujiwara T : Microanatomy-based standardization of left upper mediastinal lymph node dissection in thoracoscopic esophagectomy in the prone position. Surg Endosc , 35(1) : 349-357 , 2021
• 5.Tanabe S, Shirakawa Y, Maeda N, Sakurama K, Noma K, Fujiwara T : Paraesophageal hernia repair can decrease BNP levels. Surg Endosc, 35(12) : 6921-6929, 2021
• 6.Yano S, Tazawa H, Kishimoto H, Kagawa S, Fujiwara T, Hoffman RM : Real-Time Fluorescence Image-Guided Oncolytic Virotherapy for Precise Cancer Treatment. Int J Mol Sci, 22(2) : 879,2021
• 7.Katsube R, Noma K, Ohara T, Nishiwaki N, Kobayashi T, Komoto S, Sato H, Kashima H, Kato T, Kikuchi S, Tazawa H, Kagawa S, Shirakawa Y, Kobayashi H, Fujiwara T:Fibroblast activation protein targeted near infrared photoimmunotherapy (NIR PIT) overcomes therapeutic resistance in human esophageal cancer. Sci Rep, 11(1) : 1693, 2021
• 8.Burasakarn P, Higuchi R, Nunobe S, Kanaji S, Eguchi H, Okada KI, Fujii T, Nagakawa Y, Kanetaka K, Yamashita H, Yamada S, Kuroda S, Aoyama T, Akahori T, Nakagawa K, Yamamoto M, Yamaue H, Sho M, Kodera Y:Limited resection vs. pancreaticoduodenectomy for primary duodenal adenocarcinoma: a systematic review and meta-analysis .Int J Clin Oncol, 26(3) : 450-460, 2021
• 9.Ito A，Kagawa S, Sakamoto S, Kuwada K, Kajioka H, Yoshimoto M, Kikuchi S, Kuroda S, Yoshida R, Tazawa H, Fujiwara T：Extracellular vesicles shed from gastric cancer mediate protumor macrophage differentiation. BMC Cancer, 21(1) : 102, 2021
• 10.Takagi K, Umeda Y, Yoshida R, Yagi T, Fujiwara T, Zureikat AH, Hogg ME, Koerkamp BG：Surgical training model and safe implementation of robotic pancreatoduodenectomy in Japan: a technical note.　World J Surg Oncol, 19(1) : 55, 2021
• 11.Takagi K, Koerkamp BG：Robotic Total Pancreatectomy: A Novel Pancreatic Head-First Approach (with Video). J Gastrointest Surg, 25(6) : 1649-1650, 2021
• 12.Takagi K, Kimenai HJAN, Terkivatan T, Tran KTC, Ijzermans JNM, Minnee RC：Learning curves of minimally invasive donor nephrectomy in a high-volume center: A cohort study of 1895 onsecutive living donors. Int J Surg, 86 : 7-12, 2021
• 13.Kuroda S, Kikuchi S, Kakiuchi Y, Watanabe M, Kuwada K, Tsumura T, Nishizaki M, Kagawa S, Hinotsu S, Fujiwara T：Efficacy and safety of short-term (3 days) enoxaparin in preventing venous thromboembolism after gastric cancer surgery: A single-center, prospective cohort study. Int J Surg, 89 : 105946, 2021
• 14.Oda N, Tabata M, Uno M, Umeda Y, Kato H, Kubo T, Senoo S, Yagi T, Fujiwara T, Maeda Y, Kiura K：Dramatic Response to Carboplatin Plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis. Intern Med, 60(18) : 2967-2971, 2021
• 15.Hara T, Eguchi S, Yoshizumi T, Akamatsu N, Kaido T, Hamada T, Takamura H, Shimamura T, Umeda Y, Shinoda M, Ogura Y, Fukumoto T, Kasahara M, Hibi T, Umeshita K, Furukawa H, Ohdan H：Incidental intrahepatic cholangiocarcinoma in patients undergoing liver transplantation: A multi-center study in Japan. J Hepatobiliary Pancreat Sci, 28(4) : 346-352,2021
• 16.Kojima T, Umeda Y, Fuji T, Niguma T, Sato D, Endo Y, Sui K, Inagaki M, Oishi M, Ota T, Hioki K, Matsuda T, Aoki H, Hirai R, Kimura M, Yagi T, Fujiwara T：Efficacy of surgical management for recurrent intrahepatic cholangiocarcinoma: A multi-institutional study by the Okayama Study Group of HBP surgery.PLoS One, 15(9) : e0238392, 2021
• 17.Morisue R, Kojima M, Suzuki T, Nakatsura T, Ojima H, Watanabe R, Sugimoto M, Kobayashi S, Takahashi S, Konishi M,Ishii G, Gotohda N, Fujiwara T, Ochiai A：Sarcomatoid hepatocellular carcinoma is distinct from ordinary hepatocellular carcinoma: Clinicopathologic, transcriptomic and immunologic analyses. Int J Cancer, 149(3) : 546-560,2021
• 18.Narusaka T, Ohara T, Noma K, Nishiwaki N, Katsura Y, Kato T, Sato H, Tomono Y, Kikuchi S, Tazawa H, Shirakawa Y, Matsukawa A, Fujiwara T. Nanog is a promising chemoresistant stemness marker and therapeutic target by iron chelators for esophageal cancer. Int J Cancer, 149(2) : 347-357,2021
• 19.Omori T, Tazawa H, Yamakawa Y, Osaki S, Hasei J, Sugiu K, Komatsubara T, Fujiwara T, Yoshida A, Kunisada T, Urata Y, Kagawa S, Ozaki T, Fujiwara T：Oncolytic virotherapy promotes radiosensitivity in soft tissue sarcoma by suppressing anti-apoptotic MCL1 expression. PLoS One, 16(4) : e0250643,2021
• 20.Shirakawa Y, Noma K, Maeda N, Tanabe S, Sakurama K, Sonoyama-Hanaoka A, Yoshitomi A, Kohno-Yamanaka R, Soga Y,Fujiwara T:Early intervention of the perioperative multidisciplinary team approach decreases the adverse events during neoadjuvant chemotherapy for esophageal cancer patients. Esophagus, 18(4) : 797-805, 2021
• 21.Kikuchi S, Kagawa T, Kuroda S, Nishizaki M, Takata N, Kuwada K, Shoji R, Kakiuchi Y, Mitsuhashi T, Umeda Y, Noma K, Kagawa S, Fujiwara T：Accreditation as a qualified surgeon improves surgical outcomes in laparoscopic distal gastrectomy. Surg Today, 51(12) : 1978-1984, 2021
• 22.Matsumi Y, Kagawa T, Yano S, Tazawa H, Shigeyasu K, Takeda S, Ohara T, Aono H, Hoffman RM, Fujiwara T, Kishimoto H：Hyperthermia generated by magnetic nanoparticles for effective treatment of disseminated peritoneal cancer in an orthotopic nude-mouse model. Cell Cycle, 20(12) : 1122-1133, 2021
• 23.Sugiu K, Tazawa H, Hasei J, Yamakawa Y, Omori T, Komatsubara T, Mochizuki Y, Kondo H, Osaki S, Fujiwara T, Yoshida A, Kunisada T, Ueda K, Urata Y, Kagawa S, Ozaki T, Fujiwara T：Oncolytic virotherapy reverses chemoresistance in osteosarcoma by suppressing MDR1 expression. Cancer Chemother Pharmacol, 88(3) : 513-524, 2021
• 24.Shirakawa Y, Tazawa H, Tanabe S, Kanaya N, Noma K, Koujima T, Kashima H, Kato T, Kuroda S, Kikuchi S, Kagawa S, Katsui K, Kanazawa S, Urata Y, Fujiwara T：Phase I dose-escalation study of endoscopic intratumoral injection of OBP-301 (Telomelysin) with radiotherapy in oesophageal cancer patients unfit for standard treatments. Eur J Cancer,153 : 98-108, 2021
• 25.Fujiwara T, Yakoub MA, Chandler A, Christ AB, Yang G, Ouerfelli O, Rajasekhar VK, Yoshida A, Kondo H, Hata T, Tazawa H, Dogan Y, Moore MAS, Fujiwara T, Ozaki T, Purdue E, Healey JH：CSF-1/CSF-1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-Cell Infiltration in the Sarcoma Microenvironment. Mol Cancer Ther, 20(8) : 1388-1399, 2021
• 26.Kagawa T, Matsumi Y, Aono H, Ohara T, Tazawa H, Shigeyasu K, Yano S, Takeda S, Komatsu, Hoffman RM, Fujiwara T, Kishimoto H：Immuno-hyperthermia effected by antibody-conjugated nanoparticles selectively targets and eradicates individual cancer cells. Cell Cycle, 20(13) : 1221-1230, 2021
• 27.Beumer BR, Takagi K, Vervoort B, Buettner S, Umeda Y, Yagi T, Fujiwara T, Steyerberg EW, IJzermans JNM：Prediction of Early Recurrence After Surgery for Liver Tumor (ERASL): An International Validation of the ERASL Risk Models. Ann Surg Oncol, 28(13) : 8211-8220, 2021
• 28.Beumer BR, Takagi K, Vervoort B, Buettner S, Umeda Y, Yagi T, Fujiwara T, Steyerberg EW, IJzermans JNM：ASO Visual Abstract: Prediction of Early Hepatocellular Carcinoma Recurrence After Resection-An International Validation of the ERASL Risk Models. Ann Surg Oncol, 28 : 505-506, 2021
• 29.Takagi K, Umeda Y, Yoshida R, Yagi T, Fujiwara T：Robotic Radical Antegrade Modular Pancreatosplenectomy Using the Supracolic Anterior Superior Mesenteric Artery Approach. J Gastrointest Surg, 25(11) : 3015-3018, 2021
• 30.Kakiuchi Y, Kuroda S, Kanaya N, Kumon K, Tsumura T, Hashimoto M, Yagi C, Sugimoto R, Hamada Y, Kikuchi S, Nishizaki M, Kagawa S, Tazawa H, Urata Y, Fujiwara T：Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles. Mol Ther, 29(10) : 2920-2930, 2021
• 31.Fujiwara N, Watanabe M, Katayama A, Noda Y, Eguchi J, Kataoka H, Kagawa S, Wada J：Longitudinal observation of insulin secretory ability before and after the onset of immune checkpoint inhibitor-induced diabetes mellitus: A report of two cases. Clin Case Rep, 9(9) : e04574, 2021
• 32.Umeda Y, Mitsuhashi T, Kojima T, Satoh D, Sui K, Endo Y, Inagaki M, Oishi M, Yagi T, Fujiwara T：Impact of lymph node dissection on clinical outcomes of intrahepatic cholangiocarcinoma: Inverse probability of treatment weighting with survival analysis. J Hepatobiliary Pancreat Sci, doi:10.1002/jhbp.1038, 2021
• 33.Watanabe T, Matsumoto H, Yoshida R, Yasui K, Yagi T, Kimata Y：Pectoralis major and serratus anterior muscle flap for diaphragmatic reconstruction.Ann Thorac Surg, S0003-4975(21)01685-4. doi:10.1016/j, 2021
• 34.Zwart MJW, Jones LR, Fuente I, Balduzzi A, Takagi K, Novak S, Stibbe LA, de Rooij T, van Hilst J, van Rijssen LB, van Dieren S, Vanlander A, van den Boezem PB, Daams F, Mieog JSD, Bonsing BA, Rosman C, Festen S, Luyer MD, Lips DJ, Moser AJ, Busch OR, Abu Hilal M, Hogg ME, Stommel MWJ, Besselink MG; Dutch Pancreatic Cancer Group：Performance with robotic surgery versus 3D‑ and 2D-laparoscopy during pancreatic and biliary anastomoses in a biotissue model: pooled analysis of two randomized trials. Surg Endosc, doi:10.1007/s00464-021-08805-3,2021
• 35.Ako S, Kato H, Nouso K, Kinugasa H, Terasawa H, Matushita H, Takada S, Saragai Y, Mizukawa S, Muro S, Uchida D, Tomoda T, Matsumoto K, Horiguchi S, Nobuoka D, Yoshida R, Umeda Y, Yagi T, Okada H：Plasma KRAS mutations predict the early recurrence after surgical resection of pancreatic cancer.Cancer Biol Ther, 22(10-12) : 564-570, 2021
• 36.Shinozaki K, Yamada T, Nasu J, Matsumoto T, Yuasa Y, Shiraishi T, Nagano H, Moriyama I, Fujiwara T, Miguchi M, Yoshida R, Nozaka K, Tanioka H, Nagasaka T, Kurisu Y, Kobayashi M, Tsuchihashi K, Inukai M, Kikuchi T, Nishina T：A phase II study of FOLFOXIRI plus bevacizumab as initial chemotherapy for patients with untreated metastatic colorectal cancer: TRICC1414 (BeTRI). Int J Clin Oncol, 26(2) : 399-408, 2021
• 37.Yoshida K, Umeda Y, Iwamuro M, Matsumoto K, Kato H, Uka M, Matsui Y, Yoshida R, Kuise T, Yasui K, Takagi K, Araki H, Yagi T, Fujiwara T：Hemobilia after bile duct resection: perforation of pseudoaneurysm into intra-pancreatic remnant bile duct: a case report. BMC Surg, 20(1) : 307,2021
• 38.Hashimoto, M, Shirakawa Y, Maeda N, Tanabe S, Sakurama K, Noma, K, Fujiwara, T：A case of esophageal cancer with an aberrant right subclavian artery treated with mediastinoscopic esophagectomy. Asian J Endosc Surg, 14(2) : 293-296, 2021
• 39.Umeda H, Kikuchi S, Kuroda S, Yano S, Tanaka T, Noma K, Nishizaki M, Kagawa S, Umeda Y, Fujiwara T：Long-term survival without recurrence after surgery for gastric yolk sac tumor-like carcinoma: a case report. Surg Case Rep, 7(1) : 111, 2021
• 40.Endo M, Yano S, Asano H, Takeda S, Hamada Y, Kondo Y, Kuroda S, Shigeyasu K, Kikuchi S, Tanaka T, Teraishi F, Nishizaki M, Kagawa S, Fujiwara T：Long-term survival with a rare advanced primary gastrointestinal malignant melanoma treated with laparoscopic surgery/immune checkpoint inhibitor.Acta Med Okayama, 75(2) : 231-238, 2021
• 41.Matsuda T, Umeda Y, Yoshida K, Matsuda T, Uno M, Abe M, Asada N, Maeda Y, Yagi T, Fujiwara T：Laparoscopic hepatectomy for the patient with hemophilia A with high titer factor VIII inhibitor. Acta Med Okayama, 75(2) : 199-204, 2021
• 42.Takagi K, Umeda Y, Yoshida R, Yoshida K, Yasui K, Sato H, Yagi T, Fujiwara T：Gastroenteropancreatic neuroendocrine tumor of the accessory papilla of the duodenum: a case report. Surg Case Rep, 7(1) : 156, 2021
• 43.Sakurai Y, Kikuchi S, Shigeyasu K, Kakiuchi Y, Tanaka T, Umeda H, Sakamoto M, Takeda S, Yano S, Futagawa M, Kato F, Sogawa R, Yamamoto H, Kuroda S, Kondo Y, Teraishi F, Kishimoto H, Nishizaki M, Kagawa S, Hirasawa A, Fujiwara T：SMAD4 Germline Pathogenic Variant-Related Gastric Juvenile Polyposis with Adenocarcinoma Treated with Laparoscopic Total Gastrectomy: A Case Report.Am J Case Rep, 22 : e932241, 2021
• 44.Takagi K, Kuise T, Yoshida K, Yoshida R, Umeda Y, Fujiwara T, Yagi T：Adult Bochdalek hernia following living donor left hepatectomy repaired by thoracoscopy-assisted surgery. Asian J Endosc Surg, 15(1) : 220-224, 2021
• 45.Yoshida R, Yagi T, Yasui K, Umeda Y, Yoshida K, Fuji T, Takagi K, Kumano K, Yoshimoto M, Fujiwara T：Usefulness of Middle Colic Artery Transposition Technique for Hepatic Arterial Reconstruction in Conversion Surgery for an Initially Unresectable, Locally Advanced Pancreatic Cancer. Acta Med Okayama, 75(4) : 543-548, 2021
• 46.Takagi K, Yagi T, Fujiwara T：Splenic and Peritoneal Metastases with Para-aortic and Virchow Lymph Node Metastases: Late Recurrence of Ovarian Cancer 30 Years after Initial Treatment. JMA J, 4(4) : 428-431,2021
• 47.Takagi K, Yoshida R, Umeda Y, Yagi T：Robotic distal pancreatectomy using a medial approach for bulky mucinous cystic neoplasm of the pancreas (with video). Asian J Surg, 45(1) : 542-543,2021
• 48.Takagi K, Kanehira N, Matsumoto K：A Rare Complication of Barium Swallow Test. Gastroenterology, 162(2) : 401-403, 2021
• 49.Takagi K, Umeda Y, Yoshida R, Yagi T：Robotic spleen-preserving distal pancreatectomy using indocyanine green fluorescence imaging (with video).Asian J Surg, 45(1) : 596-597, 2021
• 50.Nagai Y, Takagi K, Kuise T, Umeda Y, Yoshida R, Yoshida K, Yasui K, Takahito Yagi, and Toshiyoshi Fujiwara：Multiple Hepatolithiasis Following Hepaticojejunostomy Successfully Treated with Left Hemihepatectomy and Double Hepaticojejunostomy Reconstruction. Acta Med Okayama, 75(6) : 735-739, 2021
• 51.Takagi K, Kuise T, Umeda Y, Yoshida R, Yoshida K, Nagai Y, Noma K, Tanabe S, Maeda N, Yagi T, Fujiwara T：Left Hemihepatectomy for Hepatocellular Carcinoma Following Esophagectomy with Retrosternal Gastric Tube Reconstruction for Esophageal Cancer. Acta Med Okayama, 75(6) : 755-758, 2021
• 52.Yano S, Tazawa H, Kishimoto H, Kagawa S, Fujiwara T, Hoffman R.M：Real-time fluorescence image-guided oncolytic virotherapy for precise cancer treatment. Int J Mol Sci, 22(2) : 879, 2021
• 53.Fujiwara T, Healey J, Yoshida A, Kondo H, Hata T, Kure M, Tazawa H, Nakata E, Kunisada T, Fujiwara T, Ozaki T ：Role of tumor-associated macrophages in sarcomas. Cancers (Basel), 13(5) : 1086, 2021
• 54.Takagi K, Koerkamp BG：Robotic Total Pancreatectomy: A Narrative Review. In Vivo, 35(4) : 1907-1911, 2021
• 55.Contarini E, Takagi K, Kimenai HJAN, Ijzermans JNM, Furian L, Rigotti P, Minnee RC：Kidney autotransplantation for renal artery aneurysm: case series and a systematic review.Ann Vasc Surg, 77 : 349, 2021

2020年

• 1.Wakabayashi K，Sakurai F，Ono R,，Fujiwara T，Mizuguchi H：Development of a novel oncolytic adenovirus expressing a short-hairpin RNA against cullin 4A.．Anticancer Res 40：161-168，2020
• 2.Kanaya N，Kuroda S，Kakiuchi Y，Kumon K，Tsumura T，Hashimoto M，Morihiro T，Kubota T，Aoyama K，Kikuchi S，Nishizaki M，Kagawa S，Tazawa H，Mizuguchi H，Urata Y，Fujiwara T：Immune modulation by telomerase-specific oncolytic adenovirus synergistically enhances antitumor efficacy with anti-PD1 antibody.．Mol Ther 28：794-804，2020
• 3.Shirakawa Y，Noma K，Maeda N，Tanabe S，Sakurama K，Fujiwara T：Microanatomy-based standardization of left upper mediastinal lymph node dissection in thoracoscopic esophagectomy in the prone position.．Surgical Endos ：doi: 10.1007/s00464-020-07407-9.-，2020
• 4.Koujima T，Tazawa H，Ieda T，Araki H，Fushimi T，Shoji R，Kuroda S，Kikuchi S，Yoshida R，Umeda Y，Teraishi F，Urata Y，Mizuguchi H，Fujiwara T：Oncolytic virus-mediated targeting of the ERK signaling pathway inhibits invasive propensity in human pancreatic cancer.．Mol Ther Oncolytics 17：107-117，2020
• 5.Tanimoto T，Tazawa H，Ieda T，Nouso H，Tani M，Oyama T，Urata Y，Kagawa S，Noda T，Fujiwara T：Elimination of MYCN-amplified neuroblastoma cells by telomerase-targeted oncolytic virus via MYCN suppression.．Mol Ther Oncolytics 18：14-23，2020
• 6.Maeda N，Shirakawa Y，Tanabe S，Sakurama K，Noma K，Fujiwara T：Skeletal muscle loss in the postoperative acute phase after esophageal cancer surgery as a new prognostic factor.．World J Surg Oncol 18（１）：doi: 10.1186/s12957-020-01908-6.-143，2020
• 7.Ishikawa W，Kikuchi S，Ogawa T，Tabuchi M，Tazawa H，Kuroda S，Noma K：Boosting replication and penetration of oncolytic adenovirus by paclitaxel eradicate peritoneal metastasis of gastric cancer.．Molecular Therapy Oncolytics 18：262-271，2020
• 8.Kojima T，Umeda Y，Fuji T，Niguma T，Sato D，Endo Y，Sui K，Inagaki M，Oishi：Efficacy of surgical management for recurrent intrahepatic cholangiocarcinoma: A multi-institutional study by the Okayama Study Group of HBP surgery.．PLoS One 15：e 0238392-，2020
• 9.Nishiwaki N，Noma K，Maeda N，Tanabe S，Sakurama K，Shirakawa Y，Fujiwara T：High incidence of tracheobronchial diverticulum in esophageal cancer patients: a retrospective survey alerting pitfall during thoracoscopic esophagectomy.．Gen Thorac Cardiovasc Surg 68：1018-1023，2020
• 10.Daiko H，Marafioti T，Fujiwara T，Shirakawa Y，Nakatsura T，Kato K，Puccio I，Hikichi T，Yoshimura S，Nakagawa T，Furukawa M，Stoeber K，Nagira M，Ide N，Kojima T：Exploratory open‑label clinical study to determine the S‑588410 cancer peptide vaccine‑induced tumor‑infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients.．Cancer Immunol Immunother 69：2247-2257，2020
• 11.Kotaka M，Saito Y，Kato T，Satake H，Makiyama A，Tsuji Y，Shinozaki K，Fujiwara T，Mizushima T，Harihara Y，Nagata N，Kurihara N，Ando M，Kusakawa G，Sakai T，Uchida Y，Takamoto M，Kimoto S，Hyodo I，：A placebo-controlled, double-blind, randomized study of recombinant thrombomodulin (ART-123) to prevent oxaliplatin-induced peripheral neuropathy.．Cancer Chemother Pharmacol 86（5）：607-618，2020
• 12.Sui K，Okabayashi T，Umeda Y，Oishi M，Kojima T，Sato D，Endo Y，Ota T，Hioki K，Inagaki M，Matsuda T，Hirai R，Kimura M，Yagi T，Fujiwara T：Prognostic Utility of the Glasgow Prognostic Score for the Long-Term Outcomes After Liver Resection for Intrahepatic Cholangiocarcinoma: A Multi-institutional Study.．World J Surg ：doi: 10.1007/s00268-020-05797-4.-，2020
• 13.Shinozaki K，Yamada T，Nasu J，Matsumoto T，Yuasa Y，Shiraishi T，Nagano H，Moriyama I，Fujiwara T，Miguchi M，Yoshida R，Nozaka K，Tanioka H，Nagasaka T，Kurisu Y，Kobayashi M，Tsuchihashi K，Inukai M，Kikuchi T，Nishina T：A phase II study of FOLFOXIRI plus bevacizumab as initial chemotherapy for patients with untreated metastatic colorectal cancer: TRICC1414 (BeTRI).．Int Clin Oncol ：doi: 10.1007/s10147-020-01811-w.-，2020
• 14.Tsumura T，Kuroda S，Nishizaki M，Kikuchi S，Kakiuchi Y，Takata N，Ito A，Watanabe M，Kuwada K，Kagawa S，Fujiwara T：Short-term and long-term comparisons of laparoscopy-assisted proximal gastrectomy with esophagogastrostomy by the double-flap technique and laparoscopy-assisted total gastrectomy for proximal gastric cancer.．PLoS One 15（11）：e0242223.-，2020
• 15.Mochizuki Y，Tazawa H，Demiya K，Kure M，Kondo H，Komatsubara T，Sugiu K，Hasei J，Yoshida A，Kunisada T，Urata Y，Kagawa S，Ozaki T，Fujiwara T：Telomerase-specific oncolytic immunotherapy for promoting efficacy of PD-1 blockade in osteosarcoma.．Cancer Immunol Immunother ：doi: 10.1007/s00262-020-02774-7.-，2020
• 16.Nishiwaki N，Noma K，Matsuda T，Maeda N，Tanabe S，Sakurama K，Shirakawa Y，Fujiwara T：Risk factor of mediastinal lymph node metastasis of Siewert type I and II esophagogastric junction carcinomas.．Langenbecks Arch Surg 405（8）：1101-1109，2020
• 17.Miyamoto K，Matsumoto K，Kato H，Yoshida R，Umeda Y，Inoue H，Tanaka T，Matsumi A，Saragai Y，Fujii Y，Yamazaki T，Uchida D，Tomoda T，Horiguchi S，Yagi T，Okada H：The efficacy of pancreatic juice cytology with liquid-based cytology for evaluating malignancy in patients with intraductal papillary mucinous neoplasm.．BMC Gastroenterol 20（1）：319-329，2020
• 18.Fukahori S，Kawahara H，Oyama T，Saito T，Shimono R，Tanaka A，Noda T，Hatori R，Fujino J，Yagi M，Japanese Pediatric Impedance Working Group (Japanese-PIG)：Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children.．Surgery Today 50（7）：664-671，2020
• 19.Kinugasa H，Teraishi F，Okada H：Intussusception Due to Intestinal Melanoma.．Clin Gastroenterol Hepatol. ：doi: 10.1016/j.cgh.2020.02.020.-，2020
• 20.Hashimoto M，Shirakawa Y，Maeda N，Tanabe S，Noma K，Sakurama K，Katsui K，Nishizaki M，Fujiwara T：Induction chemoradiotherapy including docetaxel, cisplatin, and 5-fluorouracil for locally advanced esophageal cancer.．Esophagus 17（2）：127-134，2020
• 21.Chen Y，Ohara T，Xing B，Qi J，Noma K，Matsukawa A：A Promising New Anti-Cancer Strategy: Iron Chelators Targeting CSCs.．Acta Med Okayama 74（1）：1-6，2020
• 22.Kikuchi S，Kuroda S，Nishizaki M，Kuwada K，Takata N，Kakiuchi Y，Yano S，Noma K，Kagawa S，Fujiwara T：Intracorporeal semi‐hand‐sewn Billroth I reconstruction in total laparoscopic distal gastrectomy.．Asian J Endosc Surg ：doi: 10.1111/ases.12887.-，2020
• 23.Kajioka H，Kagawa S，Ito A，Yoshimoto M，Sakamoto S，Kikuchi S，Kuroda S，Yoshida R，Umeda Y，Noma K，Tazawa H，Fujiwara T：Targeting neutrophil extracellular traps with thrombomodulin prevents pancreatic cancer metastasis.．Cancer Lett 497：1-13，2020
• 24.Shirakawa Y，Noma K，Kunitomo T，Hashimoto M，Maeda N，Tanabe S，Sakurama K，Fujiwara T：Initial introduction of robot-assisted, minimally invasive esophagectomy using the microanatomy-based concept in the upper mediastinum．Surg Endosc ：doi: 10.1007/s00464-020-08154-7.-，2020
• 25.Kubota N，Taniguchi F，Nyuya A，Umeda Y，Mori Y，Fujiwara T，Tanioka H，Tsuruta A，Yamaguchi Y，Nagasaka T：Upregulation of microRNA-31 is associated with poor prognosis in patients with advanced colorectal cancer.．Oncol Lett 19（4）：2685-2694，2020
• 26.Takagi K，Umeda Y，Yoshida R，Watanabe N，Kuise T，Yoshida K，Yasui K，Matsuda T，Fujiwara T，Yagi T：Short-term and long-term outcomes in living donors for liver transplantation: Cohort study.．Int J Surg 84：147-153，2020
• 27.Harada K，Yasuda M，Nakano Y，Yoshida K，Umeda Y，Yagi T，Yamazaki Y，Sasano H，Otsuka F：A rare case of oncocytic adrenocortical carcinoma clinically presented as an incidentaloma.．Endocr J 67（8）：883-888，2020
• 28.Takagi K，Umeda Y，Yoshida R，Yagi T，Fujiwara T：Systematic review on immunonutrition in partial pancreatoduodenectomy.．Langenbecks Arch Surg 405（5）：585-593，2020
• 29.Matsumoto K，Kato H，Kawano S，Fujiwara H，Nishida K，Harada R，Fujii M，Yoshida R，Umeda Y，Hinotsu S，Yagi T，Okada H：Efficacy and safety of scheduled early endoscopic ultrasonography-guided ethanol reinjection for patients with pancreatic neuroendocrine tumors: Prospective pilot study.．Dig Endosc 32（3）：425-430，2020
• 30.Matsuda H，Oka Y，Yoshida R，Takatsu S，Miyazaki M：Cutaneous nerve-conscious surgical repair of vascular access-related aneurysm assisted by anatomical ultrasonography in hemodialysis patients.．J Vasc Access ：doi: 10.1177/1129729820959927.-，2020
• 31.Tanabe S，Shirakawa Y：Esophageal Reconstruction with Vascular Anastomosis and Perioperative Management.．Kyobu Geka 73（10）：887-891，2020
• 32.Yamanaka-Kohno R，Shirakawa Y，Inoue-Minakuchi M，Yokoi A，Muro M，Kosaki H，Tanabe S，Fujiwara T，Morita M：Association of dental occlusal support with the Prognostic Nutritional Index in patients with esophageal cancer who underwent esophagectomy.．Esophagus ：doi: 10.1007/s10388-020-00751-8.-，2020
• 33.Yamasaki O，Takahashi E，Noda K，Kanaya N，Tanabe S，Shirakawa Y，Morizane S：Surgical site infection caused by Aeromonas hydrophila presenting as necrotizing soft tissue infection after esophagectomy.．J Dermatol 47（6）：673-676，2020
• 34.Shigeyasu K，Toden S，Ozawa T，Matsuyama T，Nagasaka T，Ishikawa T，Sahoo D，Ghosh P，Uetake H，Fujiwara T，Goel A：The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker in colorectal cancer.．Mol Cancer 19（1）：doi: 10.1186/s12943-020-01277-4.-，2020
• 35.Nishiyama K，Taira N，Mizoo T，Kochi M，Ikeda H，Iwamoto T，Shien T，Doihara H，Ishihara S，Kawai H，Kawasaki K，Ishibe Y，Ogasawara Y，Toyooka S：Influence of breast density on breast cancer risk: a case control study in Japanese women.．Breast Cancer 27（2）：277-283，2020
• 36.Iwamoto T，Kajiwara Y，Zhu Y，Iha S：Biomarkers of neoadjuvant/adjuvant chemotherapy for breast cancer.．Breast Cancer 9（3）：doi: 10.21037/cco.2020.01.06.-，2020
• 37.Takahashi Y，Iwamoto T，Suzuki Y，Kajiwara Y，Hatono M，Tsukioki T，Kawada K，Kochi M，Ikeda H，Shien T，Taira N，Matsuoka J，Doihara H，Toyooka S：Evaluation of Therapeutic Target Gene Expression Based on Residual Cancer Burden Classification After Neoadjuvant Chemotherapy for HER2-Negative Breast Cancer.．Breast Cancer 20（2）：117-124，2020
• 38.Hojo T，Masuda N，Iwamoto T，Niikura N，Anan K，Aogi K，Ohnishi T，Yamauchi C，Yoshida M，Kinoshita T，Masuoka H，Sagara Y，Sakatani T，Kojima Y，Tsuda H，Kumamaru H，Miyata H，Nakamura S：Taxane-based combinations as adjuvant chemotherapy for node-positive ER-positive breast cancer based on 2004-2009 data from the Breast Cancer Registry of the Japanese Breast Cancer Society.．Breast Cancer 27（1）：85-91，2020
• 39.Tsukioki T，Shien T，Ohtani Y，Fujihara M，Suzuki Y，Kajihara Y，Hatono M，Kawada K，Kochi M，Iwamoto T，Ikeda H，Taira N，Doihara H：Evaluation of Prognosis of Juvenile Differentiated Thyroid Carcinoma.．Breast Cancer 74（5）：401-406，2020
• 40.Ogiya R，Niikura N，Kumamaru H，Takeuchi Y，Okamura T，Kinoshita T，Aogi K，Anan K，Iijima K，Ishida T，Iwamoto T，Kawai M，Kojima Y，Sakatani T，Sagara Y，Hayashi N，Masuoka H，Yoshida M，Miyata H，Tsuda H：Breast cancer survival among Japanese individuals and US residents of Japanese and other origins: a comparative registry-based study.．Breast Cancer 184（2）：585-596，2020
• 41.Tsukioki T，Shien T，Tanaka T，Suzuki Y，Kajihara Y，Hatono M，Kawada K，Kochi M，Iwamoto T，Ikeda H，Taira N，Doihara H，Toyooka S：Influences of preoperative metformin on immunological factors in early breast cancer.．Breast Cancer 86（1）：55-63，2020
• 42.Kawada K，Taira N，Mizoo T，Suzuki Y，Kajiwara Y，Hatono M，Tsukioki T，Kochi M，Abe Y，Nishiyama K，Iwamoto T，Ikeda H，Shien T，Doihara H，Ishihara S，Kawai H，Kawasaki K，Ishibe Y，Ogasawara Y，Toyooka S：Relationships of physical and breast cancer phenotypes with three single-nucleotide polymorphisms (rs2046210, rs3757318, and rs3803662) associated with breast cancer risk in Japanese women．Breast Cancer ：doi: 10.1007/s12282-020-01185-x.-，2020
• 43.Hatono M，Ikeda H，Suzuki Y，Kajiwara Y，Kawada K，Tsukioki T，Kochi M，Suzawa K，Iwamoto T，Yamamoto H，Shien T，Yamane M，Taira N，Doihara H，Toyooka S：Effect of isoflavones on breast cancer cell development and their impact on breast cancer treatments.．Breast Cancer ：doi: 10.1007/s10549-020-05957-z.-，2020
• 44.Hirata T，Ozaki S，Tabata M，Iwamoto T，Hinotsu S，Hamada A，Motoki T，Nogami T，Shien T，Taira N，Matsuoka J，Doihara H：A Multicenter Study of Docetaxel at a Dose of 100 mg/m(2) in Japanese Patients with Advanced or Recurrent Breast Cancer.．Breast Cancer ：doi: 10.2169/internalmedicine.5089-20.-，2020
• 45.Iwamoto T，Hara F，Uemura Y，Mukai H，Watanabe T，Ohashi Y：NSAS-BC02 substudy of chemotherapy-induced amenorrhea (CIA) in premenopausal patients who received either taxane alone or doxorubicin(A) cyclophosphamide(C) followed by taxane as postoperative chemotherapy.．Breast Cancer 182（2）：325-332，2020
• 46.Iwamoto T，Fujisawa T，Shien T，Araki K，Sakamaki K，Sangai T，Kikawa Y，Takao S，Nishimura R，Takahashi M，Aihara T，Mukai H，Taira N：The efficacy of sequential second-line endocrine therapies (ETs) in postmenopausal estrogen receptor-positive and HER2-negative metastatic breast cancer patients with lower sensitivity to initial Ets.．Breast Cancer 27（5）：973-981，2020
• 47.Kikuchi S，Kuroda S，Nishizaki M，Kuwada K，Takata N，Kakiuchi Y，Yano S，Noma K，Kagawa S，Fujiwara T：Intracorporeal semi-hand-sewn Billroth I reconstruction in　total laparoscopic distal gastrectomy．Asian J Endosc Surg ：doi: 10.1111/ases.12887.-，2020
• 48.Takagi K，Kuise T，Umeda Y，Yoshida R，Teraishi F，Yagi T，Fujiwara T：Laparoscopic liver resection of segment seven: A case report and review of surgical techniques.．Int J Surg Case Rep 73：168-171，2020
• 49.Hashimoto M，Shirakawa Y，Maeda N，Tanabe S，Sakurama K，Noma K，Fujiwara T：A case of esophageal cancer with an aberrant right subclavian artery treated with mediastinoscopic esophagectomy.．Asian J Endosc Surg ：doi: 10.1111/ases.12859.-，2020
• 50.Matsumoto N，Matsusaki T，Hiroi K，Kaku R，Yoshida R，Umeda Y，Yagi T：Pediatric Living Donor Liver Transplantation for Congenital Absence of the Portal Vein With Pulmonary Hypertension: A Case Report.．Transplant Proc 52（2）：630-633，2020
• 51.Oyama T，Morimatsu H，Washio K，Shimada A：Pediatric growing teratoma syndrome of the ovary: A case report and review of the literature.．Medicine(Baltimore) 99（38）：doi: 10.1097/MD.0000000000022297.-，2020
• 52.Takagi K，Umeda Y，Kuise T，Yoshida R，Yoshida K，Yasui K，Tani Y，Yagi T：A novel modified hanging maneuver in laparoscopic left hemihepatectomy.．Int J Surg Case Rep 76：251-253，2020
• 53.Iwamuro M，Fujiwara T，Ota Y，Tanaka T，Asada N，Yano S，Uka M，Nakamura R：Intestinal Diffuse Large B-Cell Lymphoma in a Patient with Systemic Lupus Erythematosus.．Case Rep Gastrointest Med ：doi: 10.1155/2020/7947540.-，2020
• 54.Suzuki Y，Baba Y, Kawano S, Kawahara Y, Okada H，Hatono M，Kajiwara Y，Abe Y，Kawada K，Tsukioki T，Kochi M，Nishiyama K，Iwamoto T，Ikeda H，Shien T，Taira N，Tabata M，Yanai H，Doihara H：Recurring radiation-induced angiosarcoma of the breast that was treated with paclitaxel chemotherapy: a case report.．Breast Cancer 6（1）：doi: 10.1186/s40792-020-0790-7.-，2020
• 55.Tazawa H，Hasei J，Yano S，Kagawa S，Ozaki T，Fujiwara T：Bone and soft-tissue sarcoma: a new target for telomerase-specific oncolytic virotherapy.．Cancers(Basel) 12（2）：doi: 10.3390/cancers12020478.-，2020
• 56.Yano S，Tazawa H，Kagawa S，Fujiwara T，Hoffman RM：FUCCI real-time cell-cycle imaging as a guide for designing improved cancer therapy: a review of innovative strategies to target quiescent chemo-resistant cancer cells.．Cancers(Basel) 12（9）：doi: 10.3390/cancers12092655.-，2020

2019年

• 1.Hirata K, Imamura M, Fujiwara T, Fukui T, Furukawa T, Gotoh M, Hakamada K, Ishiguro M, Kakeji Y, Konno H, Miyata H, Mori M, Okita K, Sato M, Shibata A, Takemasa I, Unno M, Yokoi K, Nishidate T, Nishiyama M：Current status of site-specific cancer registry system for the clinical researches：aiming for future contribution by the assessment of present medical care.　Int. J. Clin. Oncol,　24：9-1161-1168, 2019
• 2.Kanaya N, Tanakaya K, Yamasaki R, Arata T, Shigeyasu K, Aoki H, Morito T, Sanaii H, Akagi K, Fujiwara T：Clinicopathological features of breast cancer in Japanese female patients with Lynch syndrome.　Breast Cancer,　26：3-359-364, 2019
• 3.Kono Y, Kanzaki H, Tsuzuki T, Takatani M, Nasu J, Kawai D, Takenaka R, Tanaka T, Iwamuro M, Kawano S, Kawahara Y, Fujiwara T, Okada H：A multicenter observational study on the clinicopathological features of gastric cancer in young patients.　J Gastroenterol,　54：5-419-426, 2019
• 4.Imamura M, Hirata K, Unno M, Kamiya K, Gotoh M, Konno H, Shibata A, Sugihara K, Takahashi A, Nishiyama M, Hakamada K, Fukui T, Furukawa T, Mizushima T, Mizuma M, Miyata H, Mori M, Takemasa I, Mizuguchi T, Fujiwara T：Current status of projects for developing cancer-related clinical practice guidelines in Japan and recommendations for the future. Int. J. Clin. Oncol,　24：2-189-195, 2019
• 5.Yokoyama S, Watanabe Y, Kurashima Y, Oshita A, Nishizawa Y, Naitoh T, Nakamura F, Kikuchi S, Noma K, Poudel S, Suzuki A, Nishihara Y, Ito M, Hirano S：Identifying the needs for teaching fundamental knowledge of laparoscopic surgery：a cross-sectional study in Japan.　Surg Endosc,　33：7-2242-2248, 2018
• 6.Fuji T, Umeda Y, Nyuya A, Taniguchi F, Kawai T, Yasui K, Toshima T, Yoshida K, Fujiwara T, Goel A, Nagasaka T：Detection of circulating microRNAs with Ago2 complexes to monitor the tumor dynamics of colorectal cancer patients during chemotherapy.　Int J Cancer,　144：9-2169-2180, 2019
• 7.Akazawa Y, Nobuoka D, Takahashi M, Yoshikawa T, Shinomura M, Mizuno S, Fujiwara T, Nakamoto Y, Nakatsura T：Higher human lymphocyte antigen class I expression in early-stage cancer cells leads to high sensitivity for cytotoxic T lymphocytes.　Cancer Sci,　110：6-1842-1852, 2019
• 8.Kikuchi S, Kuroda S, Nishizaki M, Matsusaki T, Kuwada K, Kimura Y, Kagawa S, Morimatsu H, Fujiwara T：Comparison of the Effects of Epidural Analgesia and Patient-controlled Intravenous Analgesia on Postoperative Pain Relief and Recovery After Laparoscopic Gastrectomy for Gastric Cancer.　Surg Laparosc Endosc Percutan Tech,　29：5-405-408, 2019
• 9.Takeda S, Shigeyasu K, Okugawa Y, Yoshida K, Mori Y, Yano S, Noma K, Umeda Y, Kondo Y, Kishimoto H, Teraishi F, Nagasaka T, Tazawa H, Kagawa S, Fujiwara T, Goel A：Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer.　Cancer Lett,　444：-127-135, 2019
• 10.Katsura Y, Ohara T, Noma K, Ninomiya T, Kashima H, Kato T, Sato H, Komoto S, Narusaka T, Tomono Y, Xing B, Chen Y, Tazawa H, Kagawa S, Shirakawa Y, Kasai T, Seno M, Matsukawa A, Fujiwara T：A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness.　Cancers (Basel),　11：2-doi：10.3390/cancers11020177, 2019
• 11.Kikuchi S, Kubota T, Kuroda S, Nishizaki M, Kagawa S, Kato H, Okada H, Fujiwara T：Endoscopic Ultrasound-Guided Transgastric Drainage of an IntraAbdominal Abscess following Gastrectomy.　Clin Endosc,　52：4-373-376, 2019
• 12.Morihiro T, Kuroda S, Kanaya N, Kakiuchi Y, Kubota T, Aoyama K, Tanaka T, Kikuchi S, Nagasaka T, Nishizaki M, Kagawa S, Tazawa H, Fujiwara T：PD-L1 expression combined with microsatellite instability/CD8+ tumor infiltrating lymphocytes as a useful prognostic biomarker in gastric cancer.　Sci Rep,　9：1-4633, 2019
• 13.Kuwada K, Kuroda S, Kikuchi S, Yoshida R, Nishizaki M, Kagawa S, Fujiwara T：Clinical Impact of Sarcopenia on Gastric Cancer.　Anticancer Res,　39：5-2241-2249, 2019
• 14.Watanabe S, Noma K, Ohara T, Kashima H, Sato H, Kato T, Urano S, Katsube R, Hashimoto Y, Tazawa H, Kagawa S, Shirakawa Y, Kobayashi H, Fujiwara T：Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma.　Cancer Biol Ther,　20：9-1234-1248, 2019
• 15.Fujiwara T：Multidisciplinary oncolytic virotherapy for gastrointestinal cancer.　Ann Gastroenterol Surg,　3：4-396-405, 2019
• 16.Yokomichi N, Nishida N, Umeda Y, Taniguchi F, Yasui K, Toshima T, Mori Y, Nyuya AT, anaka T, Yamada T, Yagi T, Fujiwara T, Yamaguchi Y, Goel A, Kudo M, Nagasaka T：Heterogeneity of Epigenetic and Epithelial Mesenchymal Transition Marks in Hepatocellular Carcinoma with Keratin 19 Proficiency.　Liver Cancer,　8：4-239-254, 2019
• 17.Ieda T, Tazawa H, Okabayashi H, Yano S, Shigeyasu K, Kuroda S, Ohara T, Noma K, Kishimoto H, Nishizaki M, Kagawa S, Shirakawa Y, Saitou T, Imamura T, Fujiwara T：Visualization of epithelial-mesenchymal transition in an inflammatory microenvironment-colorectal cancer network.　Sci Rep,　9：1-16378, 2019
• 18.Sakamoto S, Kagawa S, Kuwada K, Ito A, Kajioka H, Kakiuchi Y, Watanabe M, Kagawa T, Yoshida R, Kikuchi S, Kuroda S, Tazawa H, Fujiwara T：Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer.　Oncoimmunology,　8：12-e1671760, 2019
• 19.Matsueda K, Kanzaki H, Nasu J, Yoshioka M, Nakagawa M, Inoue M, Inaba T, Imagawa A, Takatani M, Takenaka R, Suzuki S, Tomoda J, Yagi T, Fujiwara T, Tanaka T, Okada H：The clinicopathological differences of sporadic non-ampullary duodenal epithelial neoplasm depending on tumor location.　J Gastroenterol Hepatol,　34：9-1540-1544, 2019
• 20.Matsumoto K, Ohara T, Fujisawa M, Takaki A, Takahara M, Tanaka N, Kato H, Horiguchi S, Yoshida R, Umeda Y, Fushimi S, Yagi T, Matsukawa A, Okada H：The relationship between the PD-L1 expression of surgically resected and fine-needle aspiration specimens for patients with pancreatic cancer.　J Gastroenterol,　54：11-1019-1028, 2019
• 21.Matsui Y, Fujiwara H, Hiraki T, Iguchi T, Komaki T, Tanaka T, Yagi T, Gobara H, Kanazawa S：Histological findings in non-tumoral liver and tumor after chemoembolization with drug-eluting beads. Minim Invasive Ther Allied Technol,　1-7：-doi：10.1080/13645706.2019.1626250, 2019
• 22.Hiroi K, Matsusaki T, Kaku R, Umeda Y, Yagi T, Morimatsu H：Postoperative Course of Serum Albumin Levels and Organ Dysfunction After Liver Transplantation.　Transplant Proc,　51：8-2750-2754, 2019
• 23.Matsumoto K, Kato H, Kawano S, Fujiwara H, Nishida K, Harada R, Fujii M, Yoshida R, Umeda Y, Hinotsu S, Yagi T, Okuda H：Efficacy and safety of scheduled early endoscopic ultrasonography-guided ethanol reinjection for patients with pancreatic neuroendocrine tumors：Prospective pilot study. Dig Endosc：-doi：10.1111/den.13552, 2019
• 24.Fukahori S, Kawahara H, Oyama T, Saito T, Shimono R, Tanaka A, Noda T, Hatori R, Fujino J, Yagi M：Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children.　Surg Today：-doi：10.1007/s00595-019-01833-6, 2019
• 25.Hatayama K, Washio Y, Okamura T, Noda T, Tsukahara H：Neonatal hemochromatosis associated with rupture of esophageal varices.　Pediatr Int,　61：7-735-737, 2019
• 26.Fukahori S, Kawahara H, Oyama T, Saito T, Shimono R, Tanaka A, Noda T, Hatori R, Fujino J, Yagi M：Correction to：Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children.　Surg Today： -doi：10.1007/s00595-019-01892-9, 2019
• 27.Katsura Y, Ohara T, Noma K, Ninomiya T, Kashima H, Kato T, Sato H, Komoto S, Narusaka T, Tomono Y, Xing B, Chen Y, Tazawa H, Kagawa S, Shirakawa Y, Kasai T, Seno M, Matsukawa A, Fujiwara T：A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness.　Cancers (Basel),　11：2-doi：10.3390/cancers11020177, 2019
• 28.Morita M, Matsumoto H, Shirakawa Y, Noma K, Tanabe S, Kimata Y：Flap Reconstruction for Esophageal Perforation Following Anterior Cervical Plate Fixation.　Acta Med Okayama,　73：1-77-80, 2019
• 29.Yokoi A, Ekuni D, Yamanaka R, Hata H, Shirakawa Y, Morita M：Change in tongue pressure and the related factors after esophagectomy：a short-term, longitudinal study.　Esophagus,　16：3-300-308, 2019
• 30.Watanabe S, Noma K, Ohara T, Kashima H, Sato H, Kato T, Urano S, Katsube R, Hashimoto Y, Tazawa H, Kagawa S, Shirakawa Y, Kobayashi H, Fujiwara T：Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma.　Cancer Biol Ther,　20：9-1234-1248, 2019
• 31.Takagi K, Domagala P, Hartog H, van Eijck C, Groot Koerkamp B：Current evidence of nutritional therapy in pancreatoduodenectomy：Systematic review of randomized controlled trials. Ann Gastroenterol Surg,　3：6-620-629, 2019
• 32.Takagi K, Domagala P, Porte RJ, Alwayn I, Metselaar HJ, van den Berg AP, van Hoek B, Ijzermans JNM, Polak WG：Liver retransplantation in adult recipients：Analysis of a 38-year experience in the Netherlands.　J Hepatobiliary Pancreat Sci：-doi：10.1002/jhbp.　701, 2019
• 33.Takagi K, Kimenai HJAN, IJzermans JNM, Minnee RC：Obese living kidney donors：a comparison of hand-assisted retroperitoneoscopic versus laparoscopic living donor nephrectomy.　Surg Endosc：-doi：10.1007/s00464-019-07276-x, 2019
• 34.Takagi K, Domagala P, Polak WG, Ijzermans JNM, Boehnert MU：Right posterior segment graft for living donor liver transplantation：A systematic review.　Transplant Rev (Orlando),　34：1-10.1016/ j.trre.2019.100510, 2019
• 35.Takagi K, Domagala P, Polak WG, Buettner S, Wijnhoven BPL, Ijzermans JNM：Prognostic significance of the controlling nutritional status (CONUT) score in patients undergoing gastrectomy for gastric cancer：a systematic review and meta-analysis.　BMC Surg,　19：1-doi：10. 1186/s12893-019-0593-6, 2019
• 36.Domagala P, Takagi K, Ijzermans JN, Polak WG：Grafts from selected deceased donors over 80years old can safely expand the number of liver transplants：A systematic review and meta-analysis.　Transplant Rev (Orlando),　33：4-209-218, 2019
• 37.Domagala P, Takagi K, Porte RJ, Polak WG：Order of liver graft revascularization in deceased liver transplantation：A systematic review and meta-analysis.　Surgery,　166：3-237-246, 2019
• 38.Takagi K, Domagala P, Polak WG, Buettner S, Ijzermans JNM：The Controlling Nutritional Status Score and Postoperative Complication Risk in Gastrointestinal and Hepatopancreatobiliary Surgical Oncology：A Systematic Review and Meta-Analysis.　Ann Nutr Metab,　74：4-303-312, 2019
• 39.Takagi K, Domagala P, Polak WG, Buettner S, Ijzermans JNM：Prognostic significance of the controlling nutritional status (CONUT) score in patients undergoing hepatectomy for hepatocellular carcinoma：a systematic review and meta-analysis.　BMC Gastroenterol.　19：1-211, 2019
• 40.Yoshioka T, Shien K, Takeda T, Takahashi Y, Kurihara E, Ogoshi Y, Namba K, Torigoe H, Sato H, Tomida S, Yamamoto H, Soh J, Fujiwara T, Toyooka S：Acquired resistance mechanisms to afatinib in HER2-amplified gastric cancer cells.　Cancer Sci,　110：8-2549-2557, 2019
• 41.Oki E, Emi Y, Yamanaka T, Uetake H, Muro K, Takahashi T, Nagasaka T, Hatano E, Ojima H, Manaka D, Kusumoto T, Katayose Y, Fujiwara T, Yoshida K, Unno M, Hyodo I, Tomita N, Sugihara K, Maehara Y：Randomised phase II trial of mFOLFOX6 plus bevacizumab versus mFOLFOX6 plus cetuximab as first-line treatment for colorectal liver metastasis (ATOM trial).　Br J Cancer,　121：3-222-229, 2019
• 42.Ieda T, Tazawa H, Okabayashi H, Yano S, Shigeyasu K, Kuroda S, Ohara T, Noma K, Kishimoto H, Nishizaki M, Kagawa S, Shirakawa Y, Saitou T, Imamura T, Fujiwara T：Visualization of epithelialmesenchymal transition in an inflammatory microenvironment-colorectal cancer network.　Sci Rep,　9：1-16378, 2019
• 43.Ikeda A, Takaki A, Yasunaka T, Oyama A, Adachi T, Wada N, Onishi H, Ikeda F, Shiraha H, Yoshida K, Kuise T, Nobuoka D, Yoshida R, Umeda Y, Yagi T, Fujiwara T, Okada H：Predictive Factors for Successful Vaccination Against Hepatitis B Surface Antigen in Patients Who Have Undergone Orthotopic Liver Transplantation.　Acta Med Okayama,　73：1-41-50, 2019
• 44.Takagi K, Yoshida R, Yagi T, Umeda Y, Nobuoka D, Kuise T, Hinotsu S, Matsusaki T, Morimatsu H, Eguchi J, Wada J, Senda M, Fujiwara T：Effect of an enhanced recovery after surgery protocol in patients undergoing pancreaticoduodenectomy：A randomized controlled trial.　Clinical nutrition,　38：1-174-181, 2019
• 45.Fukahori S, Kawahara H, Oyama T, Saito T, Shimono R, Tanaka A, Noda T, Hatori R, Fujino J, Yagi M：Correction to： Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children.　Surg Today：-doi：10.1007/s00595-019-01892-9, 2019
• 46.Kikuch S, Kubota T, Kuroda S, Nishizaki M, Kagawa S, Kato H, Okada H, Fujiwara T：Endoscopic ultrasound-guided transgastric drainage of an intraabdominal abscess following gastrectomy.　Clin Endosc,　52：4-373-376, 2019
• 47.Kuwada K, Kuroda S, Kikuchi S, Yoshida R, Nishizaki M, Kagawa S, Fujiwara T：Clinical Impact of Sarcopenia on Gastric Cancer.　Anticancer Res,　39：5-2241-2249, 2019
• 48.Ikeda A, Takaki A, Yasunaka T, Oyama A, Adachi T, Wada N, Onishi H, Ikeda F, Shiraha H, Yoshida K, Kuise T, Nobuoka D, Yoshida R, Umeda Y, Yagi T, Fujiwara T, Okada H：Predictive Factors for Successful Vaccination Against Hepatitis B Surface Antigen in Patients Who Have Undergone Orthotopic Liver Transplantation.　Acta Med Okayama,　73：1-41-50, 2019
• 49.Seno A, Murakami C, El-Aarag B, Iwasaki Y, Ohara T, Seno M：Cancer stem cell induction from mouse embryonic stem cells.　Oncol Lett,　18：2756-2762, 2019
• 50.Hashimoto K, Yamane M, Sugimoto S, Hirano Y, Kurosaki T, Otani S, Miyoshi K, Ohara T, Okazaki M, Yoshimura T, Oto T, Matsukawa A, Toyooka S：Negative impact of recipient SPRED2 deficiency on transplanted lung in a mouse model.　Transpl Immunol,　57：101242-, 2019
• 51.Matsumoto K, Ohara T, Fujisawa M, Takaki A, Takahara M, Tanaka N, Kato H, Horiguchi S, Yoshida R, Umeda Y, Fushimi S, Yagi T, Matsukawa A, Okada H：The relationship between the PD-L1 expression of surgically resected and fine-needle aspiration specimens for patients with pancreatic cancer.　J Gastroenterol,　54：1019-1028, 2019
• 52.Katsura Y, Ohara T, Noma K, Ninomiya T, Kashima H, Kato T, Sato H, Komoto S, Narusaka T, Tomono Y, Xing B, Chen Y, Tazawa H, Kagawa S, Shirakawa Y, Kasai T, Seno M, Matsukawa A, Fujiwara T：A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness.　Cancers,　11：117-, 2019
• 53.Ohkura T, Yoshimura T, Fujisawa M, Ohara T, Marutani R, Usami K, Matsukawa A：Spred2 Regulates High Fat Diet-Induced Adipose Tissue Inflammation, and Metabolic Abnormalities in Mice.　Front Immunol,　10：17-, 2019
• 54.Fukahori S, Kawahara H, Oyama T, Saito T, Shimono R, Tanaka A, Noda T, Hatori R, Fujino J, Yagi M：Standerd protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children.　Surgery Today, DOI：10.1007/s00595-019-01833-6, 2019(Jun 18)
• 55.Hatayama K, Washio Y, Okamura T, Noda T, Tsukahara H：Neonatal hemochromatosis associated with rupture of esophageal varices.　Pediatr Int,　61(7)：735-737, DOI：10.1111/ped.13908, 2019(Jul)

2018年

• 1.Takagi K, Yoshida R, Yagi T, Umeda Y, Nobuoka D, Kuise T, Hinotsu S, Matsusaki T, Morimatsu H, Eguchi J, Wada J, Senda M, Fujiwara T:Effect of an enhanced recovery after surgery protocol in patients undergoing pancreaticoduodenectomy: A randomized controlled trial.Clin Nutr,38:1-174-181,2018
• 2.Takagi K, Miura K, Nakanuma S, Sakamoto S, Yamamoto H, Yagi T, Eguchi S, Ohta T, Wakai T, Ohtsuka M, Uemoto S, Kasahara M, Inomata Y:Six National University Consortium in Liver Transplant Professionals Training (SNUC-LT) Program in Japan.Transplantation Proceedings,50:1-168-174,2018
• 3.Takehara Y, Nagasaka T, Nyuya A, Haruma T, Haraga J, Mori Y, Nakamura K, Fujiwara T, Boland CR, Goel A:Accuracy of four mononucleotide-repeat markers for the identification of DNA mismatch-repair deficiency in solid tumors.J Transl Med,16:1-5.doi: 10.1186/s12967-017-1376-4.
• 4.Weng W, Liu N, Toiyama Y, Kusunoki M, Nagasaka T, Fujiwara T, Wei Q, Qin H, Lin H, Ma Y, Goel A:Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer.Molecular Cancer,17:1-16.doi: 10.1186/s12943-018-0767-3.
• 5.Kuwada K, Kuroda S, Kikuchi S, Yoshida R, Nishizaki M, Kagawa S, Fujiwara T:Sarcopenia and Comorbidity in Gastric Cancer Surgery as a Useful Combined Factor to Predict Eventual Death from Other Causes.Ann Surg Oncol,25:5-1160-1166
• 6.Morikawa T, Inada R, Nagasaka T, Mori Y, Kishimoto H, Kawai T, Umeda Y, Mishima H, Goel A, Fujiwara T:BRAF V600E mutation is a predictive indicator of upfront chemotherapy for stage IV colorectal cancer.Oncol Lett,15:2-2195-2201
• 7.Kikuchi S, Kuroda S, Nishizaki M, Matsusaki T, Mitsuhashi T, Kuwada K, Kagawa S, Morimatsu H, Fujiwara T:Randomized Controlled Trial of Epidural versus Patient-controlled Intravenous Analgesia for Postoperative Pain Control after Laparoscopic Gastrectomy.Acta Medica Okayama,72:1-95-98
• 8.Shirakawa Y, Noma K, Maeda N, Ninomiya T, Tanabe S, Kikuchi S, Kuroda S, Nishizaki M, Kagawa S, Kawahara Y, Okada H, Fujiwara T:Clinical characteristics and management of gastric tube cancer after esophagectomy.Esophagus,15:180-189
• 9.Yoshioka T, Shien K, Namba K, Torigoe H, Sato H, Tomida S,Yamamoto H, Asano H, Soh J, Tsukuda K, Nagasaka T, Fujiwara T, Toyooka S:Antitumor activity of pan-HER inhibitors in HER2-positive gastric cancer. Cancer Sci,109:1166-1176
• 10.Utsumi M, Umeda Y, Yagi T, Nagasaka T, Shinoura S, Yoshida R,Nobuoka D, Kuise T, Fuji T, Takagi K, Takaki A, Fujiwara T:Risk analysis for invasive fungal infection after living donor liver transplantation: which patient needs potent prophylaxis? Dig. Surg,36:1-59-66
• 11.Mori Y,Nyuya A, Yasui K,Toshima T,Kawai T, Taniguchi F,Kimura K,Inada R,Nishizaki M, Haraga J,Nakamura K,Umeda Y,Kishimoto H, Fujiwara T,Katata Y,Yamaguchi Y,Nagasaka T:Clinical outcomes of women with ovarian metastases of colorectal cancer treated with oophorectomy with respect to their somatic mutation profiles.Oncotarget,9:23-16477-16488
• 12.Takagi K, Umeda Y, Yoshida R, Nobuoka D, Kuise T, Fushimi T,Fujiwara T, Yagi T:Preoperative controlling nutritional status score predicts mortality after hepatectomy for hepatocellular carcinoma. Dig. Surg,36:3-226-232
• 13.Yoshioka T, Iwamuro M, Takeda H, FujiwaraT:Prolonged epigastric pain caused by a leaf stem embedded in the gastric wall.Intern. Med,57:17-2497-2500
• 14.Yoshioka T, Kondo Y, Fujiwara T:Successful wound treatment using negative pressure wound therapy without primary closure in a patient undergoing highly contaminated abdominal surgery.Surg. Case Rep,4:1-85-
• 15.Kato T, Noma K, Ohara T, Kashima H, Katsura Y, Sato H, Komoto S, Katsube R, Ninomiya T, Tazawa H, Shirakawa Y, Fujiwara T:Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment.Clin Cancer Res,24:19-4820-4833
• 16.Kashima H, Noma K, Ohara T, Kato T, Katsura Y, Komoto S, Sato H, Katsube R, Ninomiya T, Tazawa H, Shirakawa Y, Fujiwara T:Cancer-associated fibroblasts (CAFs) promote the lymph node metastasis of esophageal squamous cell carcinoma.International jouanal of cancer,144:4-828-840
• 17.Takagi K, Umeda Y, Yoshida R, Nobuoka D, Kuise T, Fushimi T, Fujiwara T, Yagi T:The Outcome of Complex Hepato-Pancreato-Biliary Surgery for Elderly Patients: A Propensity Score Matching Analysis.Dig. Surg,36:4-323-330
• 18.Yagi T, Takagi K, Yoshida R, Umeda Y, Nobuoka D, Kuise T, Fujiwara T, Takaki A:New Left Lobe Transplantation Procedure with Caval Reconstruction Using an Inverted Composite Graft for Chronic Budd-Chiari Syndrome in Living-Donor Liver Transplantation-A Case Report.Transplantation Proceedings,50:4-1192-1195
• 19.Watanabe M, Kagawa S, Kuwada K, Hashimoto Y, Shigeyasu K, Ishida M, Sakamoto S, Ito A, Kikuchi S, Kuroda S, Kishimoto H, Tomida S, Yoshida R, Tazawa H, Urata Y, Fujiwara T:Integrated fluorescent cytology with nano-biologics in peritoneally disseminated gastric cancer.Cancer Sci,109:10-3263-3271
• 20.Kuwada K, Kagawa S, Yoshida R, Sakamoto S, Ito A, Watanabe M, Ieda T, Kuroda S, Kikuchi S, Tazawa H, Fujiwara T:The epithelial-to-mesenchymal transition induced by tumor-associated macrophages confers chemoresistance in peritoneally disseminated pancreatic cancer.J Exp Clin Cancer Res,37:1-307.doi: 10.1186/s13046-018-0981-2.
• 21.Saragai Y, Takaki A, Umeda Y, Matsusaki T, Yasunaka T, Oyama A, Kaku R, Nakamura K, Yoshida R, Nobuoka D, Kuise T, Takagi K, Adachi T, Wada N, Takeuchi Y, Koike K, Ikeda F, Onishi H, Shiraha H, Nakamura S, Morimatsu H, Ito H, Fujiwara T, Yagi T, Okada H:A subclinical high tricuspid regurgitation pressure gradient independent of the mean pulmonary artery pressure is a risk factor for the survival after living donor liver transplantation.BMC Gestroenterology,18:1-62-doi: 10.1186/s12876-018-0793-z.
• 22.Kubota T, Kuroda S, Kanaya N, Morihiro T, Aoyama K, Kakiuchi Y, Kikuchi S, Nishizaki M, Kagawa S, Tazawa H, Fujiwara T:HER2-targeted gold nanoparticles potentially overcome resistance to trastuzumab in gastric cancer.Int J Nanomedicine,14:6-1919-1929
• 23.Kanamitsu K, chayama K, Washio K, Yoshida R, Umeda Y, Yagi T, Shimada A:Long-term Remission of Hepatitis-associated Aplastic Anemia Possibly due to Immunosuppressive Therapy after Liver Transplantation.Acta Medica Okayama,72:5-515-518
• 24.Yagi T, Takagi K, Umeda Y, Yoshida R, Nobuoka D, Kuise T, Fujiwara T:Prognostic Factors for Pediatric Living Donor Liver Transplantation: Impact of Zero-mortality Transplant for Cholestatic Diseases.Acta Medica Okayama,72:6-567-576
• 25.Takeda S, Shigeyasu K, Okugawa Y, Yoshida K, Mori Y, Yano S, Noma K, Umeda Y, Kondo Y, Kishimoto H, Teraishi F, Nagasaka T, Tazawa H, Kagawa S, Fujiwara T, Goel A:Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer.Cancer Letters,444:127-135
• 26.Kuroda S,Choda Y,Otsuka S,Ueyama S,Tanaka N,Muraoka A,Hato S,Kimura T,Tanakaya K,Kikuchi S,Tanabe S,Noma K,Nishizaki M,Kagawa S,Shirakawa Y,Kamikawa Y,Fujiwara T:Multicenter retrospective study to evaluate the efficacy and safety of the double-flap technique as antireflux esophagogastrostomy after proximal gastrectomy (rD-FLAP Study).Annals of gastroenterologocal surgery,3:1-96-103
• 27.Fuji T,Umeda Y,Nyuya A,Taniguchi F,Kawai T,Yasui K, Toshima T,Yoshida K,Fuiwara T,Goel A,Nagasaka T:Detection of Circulating MicroRNAs with Ago2 Complexes to Monitor the Tumor Dynamics of Colorectal Cancer Patients during Chemotherapy.International Journal of Cancer,144:9-269-2180
• 28.Ohara T,Sakurama K,Hiramatsu S,Karai T,Sato T,Nishina Y:New insertion support device assisted the accurate placement of tunneled cuffed catheter: First experience of 10 cases.The journal of vasucular access,19:5-51-505
• 29.Ohara T,Tomono Y,Xing Boyi,Yingfu S,Omori K,Matsukawa A:A novel, nontoxic iron chelator, super-polyphenol, effectively induces apoptosis in human cancer cell lines.Oncotarget,9:67-32751-32760
• 30.Xu Yang, Fujisawa M,Yoshimura T,Ohara T, Sato M,Mino M, Thar Htet San, Tong Gao, Steven L. Kunkel & Matsukawa A:Spred2 Deficiency Exacerbates D-Galactosamine/Lipopolysaccharide -induced Acute Liver Injury in Mice via Increased Production of TNFα.Scientific report,8:-1-188.doi: 10.1038/s41598-017-18380-0.
• 31.Takakura M,Matsumoto T,Nakamura M,Mizumoto Y.Myojyo S,Yamazaki R,Iwadare J,Bono Y, Orisaka S,Obata T,Izuka T,Kagami K, Nakayama K,Hayakawa H,Sakurai F,Mizuguchi H,Urata Y,Fujiwara T,Kyo S,Sasagawa T,Fujiwara, H:Detection of CTCs in cervical cancer using a conditionally replicative adenovirus targeting telomerase-positive cells.Cancer Sci,109:231-240

2017年

• 1.Matsuda H, Oka Y, Yoshida R, Katsura Y, Takeuchi H, Oyama T, Takatsu S, Miyazaki M ：Arterial Access Port: A Shunt-Less Vascular Access Using a Blind-Ending Artificial Graft Anastomosed to the Brachial Artery.Ther Apher Dial.21：2-185-194,2017
• 2.Weng W, Wei Q, Toden S, Yoshida K, Nagasaka T, Fujiwara T, Cai S, Qin H, Ma Y, Goel A：Circular RNA ciRS-7 - A promising prognostic biomarker and a potential therapeutic target in colorectal cancer.Clin Cancer Res.23:14-3918-3928,2017
• 3.Takagi K, Yagi T, Yoshida R, Umeda U, Nobuoka D, Kuise T, Fujiwara T：Sarcopenia predicts postoperative infection in patients undergoing hepato-biliary-pancreatic surgery .International Journal of Surgery Open.6-12-18,2017
• 4.Takagi K, Yagi T, Shinoura S, Umeda Y, Yoshida R, Nobuoka D, Watanabe N, Kuise T, Fuji T, Araki H, Fujiwara T：Syndrome of Inappropriate Antidiuretic Hormone Secretion Following Liver Transplantation .Acta Medica Okayama.71:1-85-89,2017
• 5.Takagi K, Yagi T, Umeda Y, Shinoura S, Yoshida R, Nobuoka D, Kuise T, Araki H, Fujiwara T：Preoperative Controlling Nutritional Status (CONUT) Score for Assessment of Prognosis Following Hepatectomy for Hepatocellular Carcinoma.World J Surg.41:2353-2360,2017
• 6.Saiga M, Taira N, Kimata Y, Watanabe S, Mukai Y, Shimozuma K, Mizoo T, Nogami T, Iwamoto T, Motoki T, Shien T, Matsuoka J, Doihara H：Development of a Japanese version of the BREAST-Q and the traditional psychometric test of the mastectomy module for the assessment of HRQOL and patient satisfaction following breast surgery.Breast Cancer.24:2-288-298,2017
• 7.Hara A, Taira N, Mizoo T, Nishiyama K, Nogami T, Iwamoto T, Motoki T, Shien T, Matsuoka J, Doihara H, Ishihara S, Kawai H, Kawasaki K, Ishibe Y, Ogasawara Y, Miyoshi S：N-acetyltransferase 2 polymorphism and breast cancer risk with smoking: a case control study in Japanese women.Breast Cancer.24:2-254-262,2017
• 8.Shirakawa Y, Noma K, Maeda N, Tanabe S, Kuroda S, Kagawa S, Katsui K, Katayama N, Kanazawa S, Fujiwara T：Outcome of Radiation Monotherapy for High-risk Patients with Stage I Esophageal Cancer.Acta Medica Okayama.71:2-127-133,2017
• 9.Takagi K, Yoshida R, Yagi T, Umeda Y, Nobuoka D, Kuise T, Fujiwara T：Radiographic sarcopenia predicts postoperative infectious complications in patients undergoing pancreaticoduodenectomy.BMC Surg.17:64 DOI: 10.1186/s12893-017-0261-7,2017
• 10.Yoshida K, Umeda Y, Takaki A, Nagasaka T, Yoshida R, Nobuoka D, Kuise T, Takagi K, Yasunaka T, Okada H, Yagi T, Fujiwara T：Living Donor Liver Transplantation for Acute Liver Failure : Comparing Guidelines on the Prediction of Liver Transplantation.Acta Medica Okayama.71:5-381-390,2017
• 11.Utsumi M, Takaki A, Umeda Y, Koike K, Napier SC, Watanabe N, Shinoura S, Yoshida R, Nobuoka D, Yasunaka T, Oto T, Araki M, Yamamoto K, Fujiwara T, Yagi T：Early Chimerism After Liver Transplantation Reflects the Clinical Course of Recurrent Hepatitis C.Ann Transplant.22:156-165,2017
• 12.Sawahara H, Shiraha H, Uchida D, Kato H, Kato R, Oyama A, Nagahara T, Iwamuro M, Horiguchi S, Tsutsumi K, Mandai M, Mimura T, Wada N, Takeuchi Y, Kuwaki K, Onishi H, Nakamura S, Watanabe M, Sakaguchi M, Takaki A, Nouso K, Yagi T, Nasu Y, Kumon H, Okada H：Promising therapeutic efficacy of a novel reduced expression in immortalized cells/dickkopf-3 expressing adenoviral vector for hepatocellular carcinoma.J Gastroenterol Hepatol.32:10-1769-1777,2017
• 13.Kawano S, Takaki A, Iwamuro M, Yasunaka T, Kono Y, Miura K, Inokuchi T, Kawahara Y, Umeda Y, Yagi T, Okada H：Safety and Efficacy of Small Bowel Examination by Capsule Endoscopy for Patients before Liver Transplantation.Biomed Res Int.doi: 10.1155/2017/6418529,2017
• 14.Ninomiya T, Ohara T, Noma K, Katsura Y, Katsube R, Kashima H, Kato T, Tomono Y, Tazawa H, Kagawa S, Shirakawa Y, Kimura F, Chen L, Kasai T, Seno M, Matsukawa A, Fujiwara T：Iron depletion is a novel therapeutic strategy to target cancer stem cells.Oncotarget.8:58,2017
• 15.Aoyama K, Kuroda S, Morihiro T, Kanaya N, Kubota T, Kakiuchi Y, Kikuchi S, Nishizaki M, Kagawa S, Tazawa H, Fujiwara T：Liposome-encapsulated plasmid DNA of telomerase-specific oncolytic adenovirus with stealth effect on the immune system.Sci Rep.7:14177 doi: 10.1038/s41598-017-14717-x,2017
• 16.Kagawa S, Muraoka A, Kambara T, Nakayama H, Hamano R, Tanaka N, Noma K, Tanakaya K, Kishimoto H, Shigeyasu K, Kuroda S, Kikuchi S, Kuwada K, Nishizaki M, Shirakawa Y, Fujiwara T：A multi-institution phase II study of docetaxel and S-1 in combination with trastuzumab for HER2-positive advanced gastric cancer (DASH study).Cancer Chemother Pharmacol.81:2-387-392,2017
• 17.Noma K, Shirakawa Y, Kanaya N, Okada T, Maeda N, Ninomiya T, Tanabe S, Sakurama K, Fujiwara T：Visualized Evaluation of Blood Flow to the Gastric Conduit and Complications in Esophageal Reconstruction.J Am Coll Surg.226:3-241-251,2017
• 18.Inada R, Nagasaka T, Watanabe A, Yagi T, Mori Y, Kondo Y, Kishimoto H, Umeda Y, Fujiwara T：Comparison of outcomes between symptomatic and asymptomatic patients with colorectal cancer: a propensity score-matched analysis of surgical invasiveness, medical costs and oncological outcomes.BMJ Open Gastroenterol.4:1- doi: 10.1136/bmjgast-2017-000146,2017
• 19.Kochi M, Iwamoto T, Niikura N, Bianchini G, Masuda S, Mizoo T, Nogami T, Shien T, Motoki T, Taira N, Tokuda Y, Doihara H, Matsuoka J, Fujiwara T：Tumour-infiltrating lymphocytes (TILs)-related genomic signature predicts chemotherapy response in breast cancer.Breast Cancer Res Treat.167:1-39-47,2017
• 20.Yoshida K, Toden S, Weng W, Shigeyasu K, Miyoshi J, Turner J, Nagasaka T, Ma Y, Takayama T, Fujiwara T, Goel A：SNORA21 - An Oncogenic Small Nucleolar RNA, with a Prognostic Biomarker Potential in Human Colorectal Cancer.EBioMedicine.22:68-77,2017
• 21.Tazawa H, Kuroda S, Hasei J, Kagawa S, Fujiwara T：Impact of Autophagy in Oncolytic Adenoviral Therapy for Cancer.Int J Mol Sci.18:7-doi:10.3390/ijms18071479.18:7,2017
• 22.Kikuchi S, Kuroda S, Nishizaki M, Kagawa T, Kanzaki H, Kawahara Y, Kagawa S, Tanaka T, Okada H, Fujiwara T：Management of early gastric cancer that meet the indication for radical lymph node dissection following endoscopic resection: a retrospective cohort analysis.BMC Surg.17:1-doi: 10.1186/s12893-017-0268-0,2017
• 23.Iwamoto T, Katagiri T, Niikura N, Miyoshi Y, Kochi M, Nogami T, Shien T, Motoki T, Taira N, Omori M, Tokuda Y, Fujiwara T, Doihara H, Gyorffy B, Matsuoka J：Immunohistochemical Ki67 after short-term hormone therapy identifies low-risk breast cancers as reliably as genomic markers.Oncotarget.8:16-26122-26128,2017
• 24.Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM：GFP labeling kinetics of triple-negative human breast cancer by a killer-reporter adenovirus in 3D Gelfoam® histoculture.In Vitro Cell Dev Biol Anim.53:6-479-482,2017
• 25.Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM：High-metastatic triple-negative breast-cancer variants selected in vivo become chemoresistant in vitro.In Vitro Cell Dev Biol Anim.53:4-285-287,2017
• 26.Takehara K, Yano S, Tazawa H, Kishimoto H, Narii N, Mizuguchi H, Urata Y, Kagawa S, Fujiwara T, Hoffman RM：Eradication of melanoma in vitro and in vivo via targeting with a Killer-Red-containing telomerase-dependent adenovirus.Cell Cycle.16:16-1502-1508,2017
• 27.Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Fujiwara T, Bouvet M, Hoffman RM：Comparison of Tumor Recurrence After Resection of Highly-and Poorly-Metastatic Triple-negative Breast Cancer in Orthotopic Nude-Mouse Models.Anticancer Res.37:1-57-60,2017
• 28.Machitani M, Sakurai F, Wakabayashi K, Nakatani K, Tachibana M, Kato N, Fujiwara T, Mizuguchi H：Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-Κb.Mol Ther Oncolytics.7:76-85,2017
• 29.Sakae H, Kanzaki H, Nasu J, Akimoto Y, Matsueda K, Yoshioka M, Nakagawa M, Hori S, Inoue M, Inaba T, Imagawa A, Takatani M, Takenaka R, Suzuki S, Fujiwara T, Okada H：The characteristics and outcomes of small bowel adenocarcinoma: a multicentre retrospective observational study.Br J Cancer.117:11-1607-1613,2017
• 30.Yamakawa Y, Tazawa H, Hasei J, Osaki S, Omori T, Sugiu K, Komatsubara T, Uotani K, Fujiwara T, Yoshida A, Kunisada T, Urata Y, Kagawa S, Ozaki T, Fujiwara T：Role of zoledronic acid in oncolytic virotherapy: Promotion of antitumor effect and prevention of bone destruction.Cancer Sci.108:9-1870-1880,2017
• 31.Shindo Y, Hazama S, Suzuki N, Iguchi H, Uesugi K, Tanaka H, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Takenouchi H, Matsui H, Kanekiyo S, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Fujita T, Kawakami Y, Nakamura Y, Oka M, Nagano H：Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.J Exp Clin Cancer Res.36:1-doi: 10.1186/s13046-017-0509-1,2017
• 32.Suzuki N, Hazama S, Iguchi H, Uesugi K, Tanaka H, Hirakawa K, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Shimizu R, Hayashi H, Sakata K, Takenouchi H, Matsui H, Shindo Y, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Nakamura Y, Oka M, Nagano H：Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.Cancer Sci.108:1-73-80,2017
• 33.Machitani M, Sakurai F, Wakabayashi K, Tachibana M, Fujiwara T, Mizuguchi H：Enhanced Oncolytic Activities of the Telomerase-Specific Replication-Competent Adenovirus Expressing Short-Hairpin RNA against Dicer.Mol Cancer Ther.16:1-251-259,2017
• 34.Hayashi N, Iwamoto T, Qi Y, Niikura N, Santarpia L, Yamauchi H, Nakamura S, Hortobagyi GN, Pusztai L, Symmans WF, Ueno NT：Bone metastasis-related signaling pathways in breast cancers stratified by estrogen receptor status.J Cancer.8:6-1045-1052,2017
• 35.Takakura M, Matsumoto T, Nakamura M, Mizumoto Y, Myojyo S, Yamazaki R, Iwadare J, Bono Y, Orisaka S, Obata T, Iizuka T, Kagami K, Nakayama K, Hayakawa H, Sakurai F, Mizuguchi H, Urata Y, Fujiwara T, Kyo S, Sasagawa T, Fujiwara H：Detection of circulating tumor cells in cervical cancer using a conditionally replicative adenovirus targeting telomerase-positive cells.Cancer Sci.109:1-231-240,2017
• 36.Yano S, Takehara K, Kishimoto H, Tazawa H,Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman R.M. ：OBP-401-GFP telomerase-dependent adenovirus illuminates and kills high-metastatic more effectively than low-metastatic triple-negative breast cancer in vitro. Cancer Gene Therapy .20:2-45-47,2017
• 37.Takagi K, Yagi T, Umeda Y, Yoshida R, Nobuoka D, Kuise T, Kumano K, Kojima T, Fushimi T, Fujiwara T：A novel intestinal rotation method for digestive reconstruction after combined pancreaticoduodenectomy and extended right hemicolectomy: A case report and surgical technique.Int J Surg Case Rep.39:51-55,2017
• 38.Takagi K, Yagi T, Tanaka T, Umeda Y, Yoshida R, Nobuoka D, Kuise T, Fujiwara T：Primary pancreatic-type acinar cell carcinoma of the jejunum with tumor thrombus extending into the mesenteric venous system: a case report and literature review.BMC Surg.17:75-doi: 10.1186/s12893-017-0273-3,2017
• 39.Higuchi Y, Motoki T, Ishida H, Kanamitsu K, Washio K, Oyama T, Noda T, Tsurumaru Y, Okada A, Tsukahara H, Shimada A：Sorafenib treatment for papillary thyroid carcinoma with diffuse lung metastases in a child with autism spectrum disorder: a case report.BMC Cancer.17:775-doi: 10.1186/s12885-017-3782-7,2017
• 40.Kanaya N, Noma K, Okada T, Maeda N, Tanabe S, Sakurama K, Shirakawa Y, Fujiwara T：A case of long-term survival after surgical resection for solitary adrenal recurrence of esophageal squamous carcinoma.Surg Case Rep.3:61-doi: 10.1186/s40792-017-0337-8,2017
• 41.Kagawa T, Kobayashi T, Ueyama S, Okabayashi H, Ogino T, Fujiwara T：Successful management of unresectable small bowel lymphoma with laparoscopy-assisted surgical exclusion of the affected intestine.Asian J Endosc Surg.10:4-454-458,2017

2016年

• 1.Tazawa H, Kagawa S, Shigeyasu K, Fujiwara T：Telomerase-targeted replicative adenoviruses for cancer treatnment and diagnosis　「Advances inMedicine and Biology. Vol.110」 （Berhardt, L. V., ed.）
  Nova Publishers, Inc.,　pp95-113,　New York,　2016
• 2.Tazawa H, Kagawa S, Fujiwara T：p53 replacement therapy for cancer　「Current Strategies in Cancer Gene Therapy」　（Walther, W., ed.）　Springer International Publishing,　pp1-15,　Switzerland,　2016
• 3.Sugihara M, Sadamori H, Nishibori M, Sato Y, Tazawa H, Shinoura S, Umeda Y, Yoshida R, Nobuoka D, Utsumi M, Ohno K, Nagasaka T, Yoshino T, Takahashi HK, Yagi T, Fujiwara T： Anti–high mobility group box 1 monoclonal antibody improves ischemia/reperfusion injury and mode of liver regeneration after partial hepatectomy.　Am J Surg,　211(1)：179–188,　2016
• 4.Ishida M, Kagawa S, Shimoyama K, Takehara K, Noma K, Tanabe S, Shirakawa Y, Tazawa H, Kobayashi H, Fujiwara T：Trastuzumab-based photoimmunotherapy integrated with viral HER2 transduction inhibits peritoneally disseminated HER2-negative cancer.　Mol Cancer Ther,　DOI: 10.1158/1535-7163,　2016
• 5.Yano S, Takehara K, Miwa S, Kishimoto H, Hiroshima Y, Murakami T, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM：Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model.　PLoS One,　11(2)：doi: 10.1371/journal.pone.0148760, 2016
• 6.Takagi K, Yagi T, Yoshida R, Shinoura S, Umeda Y, Nobuoka D, Watanabe N, Kuise T, Sui K, Hirose A, Tsuboi M, Ogasawara M, Iwasaki S, Saibara T, Fujiwara T：A successful case of deceased donor liver transplantation for a patient with intrahepatic arterioportal fistula. Hepatol Res, doi: 10.1111/hepr.12701,　2016
• 7.Kawai M, Tomotaki A, Miyata H, Iwamoto T, Niikura N, Anan K, Hayashi N, Aogi K, Ishida T, Masuoka H, Iijima K, Masuda S, Tsugawa K, Kinoshita T, Nakamura S, Tokuda Y. ：Body mass index and survival after diagnosis of invasive breast cancer: a study based on the Japanese National Clinical Database-Breast Cancer Registry. Cancer medicine, 5(6)：1328-1340, 2016
• 8.Yoshida K, Nagasaka T, Umeda Y, Tanaka T, Kimura K, Taniguchi F, Fuji T, Shigeyasu K, Mori Y, Yanai H, Yagi T, Goel A, Fujiwara T：Expansion of epigenetic alterations in EFEMP1 promoter predicts malignant formation in pancreatobiliary intraductal papillary mucinous neoplasms. J Cancer Res Clin Oncol, 142(7)：1557-1569,　2016
• 9.Takagi K, Yagi T, Yoshida R, Shinoura S, Umeda Y, Nobuoka D, Kuise T, Watanabe N, Sui K, Fuji T, Fujiwara T：Surgical Outcome of Patients Undergoing Pancreaticoduodenectomy: Analysis of a 17‒Year Experience at a Single Center.　Acta Medica Okayama, 70(3)：197-203, 2016
• 10.Urano S, Ohara T, Noma K, Katsube R, Ninomiya T, Tomono Y, Tazawa H, Kagawa S, Shirakawa Y, Kimura F, Nouso K, Matsukawa A, Yamamoto K, Fujiwara T：Iron depletion enhances the effect of sorafenib in hepatocarcinoma. Cancer Biol Ther,　17(6)：648-656, 2016
• 11.Nishitani S, Noma K, Ohara T, Tomono Y, Watanabe S, Tazawa H, Shirakawa Y, Fujiwara T：Iron depletion-induced downregulation of N-cadherin expression inhibits invasive malignant phenotypes in human esophageal cancer.　Int J Oncol,　49(4)：1351-1359, 2016
• 12.Takagi K, Yagi T, Yoshida R, Shinoura S, Umeda Y, Nobuoka D, Kuise T, Watanabe N, Fujiwara T：Sarcopenia and American Society of Anesthesiologists Physical Status in the Assessment of Outcomes of Hepatocellular Carcinoma Patients Undergoing Hepatectomy. Acta Medica Okayama, 70(5)：363-370, 2016
• 13.Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM：Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models. Oncotarget, DOI: 10.18632/oncotarget.13296, 2016
• 14.Kuroda S, Kikuchi S, Hori N, Sakamoto S, Kagawa T, Watanabe M, Kubota T, Kuwada K, Ishida M, Kishimoto H, Uno F, Nishizaki M, Kagawa S, Fujiwara T：Training system for laparoscopy-assisted distal gastrectomy . Surg Today,　DOI 10.1007/s00595-016-1439-9, 2016
• 15.Yano S, Takehara K, Tazawa H, Kishimoto H, Kagawa S, Fujiwara T, Hoffman RM：Comparison of in vitro invasiveness of high- and low-metastatic triple-negative human breast cancer visualized by color-coded imaging. In Vitro Cell Dev Biol Anim, DOI: 10.1007/s11626-016-0092-3, 2016
• 16.Kuroda S, Kikuchi S, Nishizaki M, Kagawa S, Hinotsu S, Fujiwara T：A Phase II Clinical Trial of the Efficacy and Safety of Short-term (3 days) Enoxaparin for the Prevention of Venous Thromboembolism after Gastric Cancer Surgery. Acta Medica Okayama, 70(5)：401-404, 2016
• 17.Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM：Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence. Oncotarget, 7(46)：75635-75647, 2016
• 18.Yano S, Takehara K, Tazawa H, Kishimoto H, Urata Y, Kagawa S, Fujiwara T, Hoffman RM：Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam®-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging. PLoS One,　doi: 10.1371/journal.pone.0162991, 2016
• 19.Yano S, Takehara K, Tazawa H, Kishimoto H, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM：Enhanced Metastatic Recurrence Via Lymphatic Trafficking of a High-Metastatic Variant of Human Triple-Negative Breast Cancer After Surgical Resection in Orthotopic Nude Mouse Models. Journal of Cellular Biochemistry, doi: 10.1002/jcb.25735,　2016
• 20.Kikuchi S, Nishizaki M, Kuroda S, Tanabe S, Noma K, Kagawa S, Shirakawa Y, Kato H, Okada H, Fujiwara T：Nonexposure laparoscopic and endoscopic cooperative surgery (closed laparoscopic and endoscopic cooperative surgery) for gastric submucosal tumor.　Gastric Cancer, DOI 10.1007/s10120-016-0641-1, 2016
• 21.Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM：In Vivo Isolation of a Highly-aggressive Variant of Triple-negative Human Breast Cancer MDA-MB-231 Using Serial Orthotopic Transplantation . Anticancer Research, 36(8)：3817-3820,　2016
• 22.Kikuchi S, Kagawa S, Ohara T, Kubota T, Kuwada K, Kagawa T, Kuroda S, Shirakawa Y, Nishizaki M, Fujiwara T：Recurrence after Endoscopic Curative Resection of Mucosal Gastric Cancer Associated with an Adjacent Neoplastic Precursor Lesion.　Acta Medica Okayama,　70(3)：213-216, 2016
• 23.Yano S, Takehara K, Tazawa H, Kishimoto H, Urata Y, Kagawa S, Fujiwara T, Hoffman RM：Therapeutic efficacy in vivo of a telomerase-dependent adenovirus in an orthotopic model of chemotherapy-resistant human stomach carcinomatosis peritonitis visualized with cell cycle color coding FUCCI imaging.　Journal of Cellular Biochemistry,　doi: 10.1002/jcb.25593, 2016
• 24.Kuroda S, Nishizaki M, Kikuchi S, Noma K, Tanabe S, Kagawa S, Shirakawa Y, Fujiwara T：Double-Flap Technique as an Antireflux Procedure in Esophagogastrostomy after Proximal Gastrectomy. J Am Coll Surg, 223(2)：e7-e13, 2016
• 25.Yano S, Takehara K, Zhao M, Tan Y, Han Q, Li S, Bouvet M, Fujiwara T, Hoffman RM：Tumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging. Cell Cycle, 15(13)：1715-1723, 2016
• 26.Horiguchi S, Kato H, Shiraha H, Tsutsumi K, Yamamoto N, Matsumoto K, Tomoda T, Uchida D, Akimoto Y, Mizukawa S, Tanaka T, Ichimura K, Takaki A, Yagi T, Okada H：Dynamic computed tomography is useful for prediction of pathological grade in pancreatic neuroendocrine neoplasm. J Gastroenterol Hepatol, doi: 10.1111/jgh.13594,　2016
• 27.Akimoto Y, Kato H, Matsumoto K, Harada R, Oda S, Fushimi S, Mizukawa S, Yabe S, Uchida D, Seki H, Tomoda T, Yamamoto N, Horiguchi S, Tsutsumi K, Yagi T, Okada H ：Pancreatic Hepatoid Carcinoma Mimicking a Solid Pseudopapillary Neoplasm: A Challenging Case on Endoscopic Ultrasound-guided Fine-needle Aspiration. Intern Med,　55(17)：2405-2411,　2016
• 28.Uchida D, Takaki A, Ishikawa H, Tomono Y, Kato H, Tsutsumi K, Tamaki N, Maruyama T, Tomofuji T, Tsuzaki R, Yasunaka T, Koike K, Matsushita H, Ikeda F, Miyake Y, Shiraha H, Nouso K, Yoshida R, Umeda Y, Shinoura S, Yagi T, Fujiwara T, Morita M, Fukushima M, Yamamoto K, Okada H： Oxidative stress balance is dysregulated and represents an additional target for treating cholangiocarcinoma. Free Radic Res, 50(7)：732-743, 2016
• 29.Kataoka J, Shiraha H, Horiguchi S, Sawahara H, Uchida D, Nagahara T, Iwamuro M, Morimoto H, Takeuchi Y, Kuwaki K, Onishi H, Nakamura S, Takaki A, Nouso K, Yagi T, Yamamoto K, Okada H：Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma. Oncology Reports, 35(5)：2576–2582, 2016
• 30.Katayama Y, Motoki T, Watanabe S, Miho S, Kimata Y, Matsuoka J, Doihara H, Nanba Y：A very rare case of breast cancer in a female-to-male transsexual. Breast Cancer, 23(6)：939-944, 2016
• 31.Tamura T, Hirata T, Tabata M, Hinotsu S, Hamada A, Motoki T, Iwamoto T, Mizoo T, Nogami T, Shien T, Taira N, Matsuoka J, Doihara H：A Phase I Trial of 100mg/m2 Docetaxel in Patients with Advanced or Recurrent Breast Cancer. Acta Medica Okayama,　70(5)：425-427, 2016
• 32.Yoshitomi S, Taira N, Doihara H, Mizoo T, Nogami T, Iwamoto T, Motoki T, Shien T, Ogasawara Y, Matsuoka J, Tsuji H, Mitsuhashi T：A phase 1, dose-finding and pharmacokinetic study of gemcitabine with nab-paclitaxel in patients with metastatic breast cancer. Cancer Chemother Pharmacol, 78(2)：289-294, 2016
• 33.Gobara H, Hiraki T, Iguchi T, Fujiwara H, Nagasaka T, Kishimoto H, Tanaka T, Kanazawa S ：Acute Bowel Injury due to Cryoablation for Renal Cell Carcinoma: Correlated Radiologic and Pathologic Findings. Acta Medica Okayama, 70(6)：511-514,　2016
• 34.Tsuruta A, Yamashita K, Tanioka H, Tsuji A, Inukai M, Yamakawa T, Yamatsuji T, Yoshimitsu M, Toyota K, Yamano T, Nagasaka T, Okajima M：Feasibility of sequential adjuvant chemotherapy with a 3-month oxaliplatin-based regimen followed by 3 months of capecitabine in patients with stage III and high-risk stage II colorectal cancer: JSWOG-C2 study.　Drug Des Devel Ther, 10：3827-3835, 2016
• 35.Yano S, Takehara K, Tazawa H, Kishimoto H, Urata Y, Kagawa S, Fujiwara T, Hoffman RM：Cell-cycle-dependent drug-resistant quiescent cancer cells induce tumor angiogenesis after chemotherapy as visualized by real-time FUCCI imaging. Cell Cycle, DOI: 10.1080/15384101.2016.1220461, 2016
• 36.Kikuchi S, Nishizaki M, Kuroda S, Kagawa S, Fujiwara T：A case of right-sided Bochdalek hernia incidentally diagnosed in a gastric cancer patient. BMC Surg, 16(34)：doi: 10.1186/s12893-016-0145-2, 2016
• 37.Matsuda H, Oka Y, Yoshida R, Katsura Y, Oyama T, Katsube R, Takatsu S, Miyazaki M ：Application of ultrasound-guided selective sensory nerve block for　the endovascular treatment of hemodialysis fistula in the forearm. J Vasc Access,　17(5)：doi: 10.5301/jva.5000578, 2016
• 38.Matsuda H, Oka Y, Takatsu S, Katsube R, Yoshida R, Oyama T, Takeda Y, Miyazaki M：Ultrasound-guided block of selective branches of the brachial plexus for vascular access surgery in the forearm: a preliminary report.　J Vasc Access, 17(3)：284-290, 2016
• 39.Ogiya R, Niikura N, Kumaki N, Bianchini G, Kitano S, Iwamoto T, Hayashi N, Yokoyama K, Oshitanai R, Terao M, Morioka T, Tsuda B, Okamura T, Saito Y, Suzuki Y, Tokuda Y：Comparison of Tumour-infiltrating Lymphocytes between Primary and Metastatic Tumours in Breast Cancer Patients. Cancer Sci,　107(12)：1730-1735,　2016
• 40.Hadad SM, Jordan LB, Roy PG, Purdie CA, Iwamoto T, Pusztai L, Moulder-Thompson SL, Thompson AM：A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer.　BMC Cancer,　16(1)：745, 2016
• 41.Kataoka A, Iwamoto T, Tokunaga E, Tomotaki A, Kumamaru H, Miyata H, Niikura N, Kawai M, Anan K, Hayashi N, Masuda S, Tsugawa K, Aogi K, Ishida T, Masuoka H, Iijima K, Kinoshita T, Nakamura S, Tokuda Y：Young adult breast cancer patients have a poor prognosis independent of prognostic clinicopathological factors: a study from the Japanese Breast Cancer Registry . Breast Cancer Res Treat, 160(1)：163-172, 2016
• 42.Iwamoto T, Kumamaru H, Miyata H, Tomotaki A, Niikura N, Kawai M, Anan K, Hayashi N, Masuda S, Tsugawa K, Aogi K, Ishida T, Masuoka H, Iijima K, Matsuoka J, Doihara H, Kinoshita T, Nakamura S, Tokuda Y：Distinct breast cancer characteristics between screen- and self-detected breast cancers recorded in the Japanese Breast Cancer Registry. Breast Cancer Res Treat, 156(3)：485-494, 2016
• 43.Niikura N, Tomotaki A, Miyata H, Iwamoto T, Kawai M, Anan K, Hayashi N, Aogi K, Ishida T, Masuoka H, Iijima K, Masuda S, Tsugawa K, Kinoshita T, Nakamura S, Tokuda Y ：Changes in tumor expression of HER2 and hormone receptors status after neoadjuvant chemotherapy in 21,755 patients from the Japanese breast cancer registry.　Ann Oncol,　27(3)：480-487, 2016
• 44.Koi M, Garcia M, Choi C, Kim HR, Koike J, Hemmi H, Nagasaka T, Okugawa Y, Toiyama Y, Kitajima T, Imaoka H, Kusunoki M, Chen YH, Mukherjee B, Boland CR, Carethers JM：Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis.　Gastroenterology, 150(4)：944-955,　2016
• 45.Saito Y, Hinoi T, Ueno H, Kobayashi H, Konishi T, Ishida F, Yamaguchi T, Inoue Y, Kanemitsu Y, Tomita N, Matsubara N, Komori K, Kotake K, Nagasaka T, Hasegawa H, Koyama M, Ohdan H, Watanabe T, Sugihara K, Ishida H：Risk Factors for the Development of Desmoid Tumor After Colectomy in Patients with Familial Adenomatous Polyposis: Multicenter Retrospective Cohort Study in Japan. Annals of surgical oncology,　23：559-565,　2016
• 46.Nagasaka T, Mishima H, Sawaki A, Shimokawa M, Inukai M, Shinozaki K, Tanioka H, Nasu J, Nishina T, Hazama S, Okajima M, Yamaguchi Y：Protocol of a randomised phase III clinical trial of sequential capecitabine or 5-fluorouracil plus bevacizumab (Cape/5-FU-Bmab) to capecitabine or 5-fluorouracil plus oxaliplatin plus bevacizumab (CapeOX/mFOLFOX6-Bmab) versus combination CapeOX/mFOLFOX6-Bmab in advanced colorectal cancer: the C-cubed (C3) study. BMJ open, doi: 10.1136/bmjopen-2016-011454, 2016
• 47.Nakamura K, Nagasaka T, Nishida T, Haruma T, Ogawa C, Kusumoto T, Seki N, Hiramatsu Y：Neutrophil to lymphocyte ratio in the pre-treatment phase of final-line chemotherapy predicts the outcome of patients with recurrent ovarian cancer. Oncology letters, 11(6)：3975-3981, 2016
• 48.Sakurai J, Matsui Y, Hiraki T, Iguchi T, Fujiwara H, Gobara H, Mitsuhashi T, Nagasaka T, Kanazawa S：Single Center Prospective Phase II Trial of CT-guided Radiofrequency Ablation for Pulmonary Metastases from Colorectal Cancer (SCIRO-1401).　Acta medica Okayama,　70(4)：317-321, 2016
• 49.Ueno H, Kobayashi H, Konishi T, Ishida F, Yamaguchi T, Hinoi T, Kanemitsu Y, Inoue Y, Tomita N, Matsubara N, Komori K, Ozawa H, Nagasaka T, Hasegawa H, Koyama M, Akagi Y, Yatsuoka T, Kumamoto K, Kurachi K, Tanakaya K, Yoshimatsu K, Watanabe T, Sugihara K, Ishida H： Prevalence of laparoscopic surgical treatment and its clinical outcomes in patients with familial adenomatous polyposis in Japan. International journal of clinical oncology, 21(4)：713-722, 2016
• 50.Omae K, Hiraki T, Gobara H, Iguchi T, Fujiwara H, Matsui Y, Toyooka S, Nagasaka T, Kanazawa S：Long-Term Survival after Radiofrequency Ablation of Lung Oligometastases from Five Types of Primary Lesions: A Retrospective Evaluation.　Journal of vascular and interventional radiology, 27(9)：1362-1370, 2016
• 51.Sakurai F, Narii N, Tomita K, Togo S, Takahashi K, Machitani M, Tachibana M, Ouchi M, Katagiri N, Urata Y, Fujiwara T, Mizuguchi H：Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus . Mol Ther. Methods Clin. Dev, 3:16001, 2016
• 52.Isozaki H, Matsumoto S, Murakami S, Takama T, Sho T, Ishihara K, Sakai K, Takeda M, Nakada K, Fujiwara T：Diminished gastric resection preserves better quality of life in patients with early gastric cancer. Acta Medica Okayama, 70(2)：119-130, 2016
• 53.Osaki S, Tazawa H, Hasei J, Yamakawa Y, Omori T, Sugiu K, Komatsubara T, Fujiwara T, Sasaki T, Kunisada T, Yoshida A, Urata Y, Kagawa S, Ozaki T, Fujiwara T：Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas. Sci Rep, 6:28953： doi: 10.1038/srep28953,　2016
• 54.Kumano K, Nishinakamura H, Mera T, Itoh T, Takahashi H, Fujiwara T, Kodama S：Pretreatment of donor islets with papain improves allograft survival without systemic immunosuppression in mice. Islets, 8(5)：145-155, 2016
• 55.Onishi T, Tazawa H, Hashimoto Y, Takeuchi M, Otani T, Nakamura S, Sakurai F, Mizuguchi H, Kishimoto H, Umeda Y, Shirakawa Y, Urata Y, Kagawa S, Fujiwara T：Tumor-specific delivery of biologics by a novel T-cell line HOZOT.　Ｓｃｉ Rep,　6:38060　：doi: 10.1038/srep38060,　2016

2015年

• 1.Takaki A, Yagi T, Yamamoto K：Safe and cost-effective control of post-transplantation recurrence of hepatitis B. Hepatol Res, 45(1)：38-47, 2015
• 2.Satoh D, Sadamori H, Yagi T, Fujiwara T：Enlarging lymphoepithelial cyst of the pancreas during 12 months of observation: report of a case. Surg Today, 45(1)：101-104, 2015
• 3.Sakakihara I, Kato H, Muro S, Noma Y, Yamamoto N, Harada R, Horiguchi S, Tsutsumi K, Okada H, Yamamoto K, Sadamori H, Yagi T：Double-balloon enteroscopy for choledochojejunal anastomotic stenosis after hepato-biliary-pancreatic operation. Digestive Endoscopy, 27(1)：146-154, 2015
• 4.Koike K, Takaki A, Yagi T, Iwasaki Y, Yasunaka T, Sadamori H, Shinoura S, Umeda Y, Yoshida R, Sato D, Nobuoka D, Utsumi M, Miyake Y, Ikeda F, Shiraha H, Fujiwara T, Yamamoto K：Enhancement of Programmed Death Ligand 2 on Hepatitis C Virus Infected Hepatocytes by Calcineurin Inhibitors. Transplantation, 99(7)：1447-1454, 2015
• 5.Inada R, Nagasaka T, Toshima T, Mori Y, Kondo Y, Kishimoto H, Hiraki T, Oshiro T, Kanemitsu Y, Fujiwara T：Aggressive multimodality treatment for advanced rectal cancer. Acta Medica Okayama, 69(2)：113-118, 2015
• 6.Inada R, Sekine S, Taniguchi T, Tsuda H, Katai H, Fujiwara T, Kushima R：ARID1A expression in gastric adenocarcinoma: Clinicopathological significance and correlation with DNA mismatch repair status. World Journal of Gastroenterology, 21(7) ：2159-2168, 2015
• 7.Shimoyama K, Kagawa S, Ishida M, Watanabe S, Noma K, Takehara K, Tazawa H, Hahimoto Y, Tanabe S, Matsuoka J, Kobayashi H, Fujiwara T：Viral transduction of the HER2-extracellular domain expands trastuzumab-based photoimmunotherapy for HER2 negative breast cancer cells. Breast Cancer Res Treat, 149(3)：597-605, 2015
• 8.Utsumi M, Umeda Y, Takagi K, Kuise T,Yoshida R, Nobuoka D, Shinoura S, Sadamori H, Yagi T, Fujiwara T：Correlation of computed tomography imaging features and pathological features of 41 patients with pancreatic neuroendocrine tumors. Hepatogastroenterology, 62(138)：441-446, 2015
• 9.Mori Y, Nagasaka T, Mishima H, Umeda Y, Inada R, Kishimoto H, Goel A, Fujiwara T：The rare BRAF VK600-601E mutation as a possible indicator of poor prognosis in rectal carcinoma – a report of a case. BMC Med Genet, 16(1)：10.1186/s12881-015-0144-7, 2015
• 10.Shirakawa Y, Noma K, Koujima T, Maeda N, Tanabe S, Ohara T, Fujiwara T：Prone-position thoracoscopic resection of posterior mediastinal lymph node metastasis from rectal cancer. World J Surg Oncol,13(45)：doi:10.1186/s12957-015-0466-0, 2015
• 11.Yano S, Zhang Y, Zhao M, Hiroshima Y, Miwa S, Uehara F, Kishimoto H, Tazawa H, Bouvet M, Fujiwara T, Hoffman RM：Tumor-targeting salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy. Cell Cycle, 13(24)：3958-3963, 2015
• 12.Yamatsuji T, Fujiwara Y, Matsumoto H, Hato S, Namikawa T, Hanazaki K, Takaoka M, Hayashi J, Shigemitsu K, Yoshida K, Urakami A, Uno F, Nishizaki M, Kagawa S, Ninomiya M, Fujiwara T, Hirai T, Nakamura M, Haisa M, Naomoto Y：Feasibility of oral administration of S-1 as adjuvant chemotherapy in gastric cancer: 4-week S‑1 administration followed by 2-week rest vs. 2-week administration followed by 1-week rest. Mol Clin Oncol, 3(3)：527-532, 2015
• 13.Toda K, Nagasaka T, Umeda Y, Tanaka T, Kawai T, Fuji T, Taniguchi F, Yasui K, Kubota N, Takehara Y, Tazawa H, Kagawa S, Sun DS, Nishida N, Goel A, Fujiwara T：Genetic and epigenetic alterations of netrin-1 receptors in gastric cancer with chromosomal instability. Clin Epigenetics,　doi:10.1186/s13148-015-0096-y, 2015
• 14.Shirakawa Y, Noma K, Koujima T, Maeda N, Tanabe S, Ohara T, Sakurama K, Fujiwara T：Operative technique of antethoracic esophageal reconstruction with pedicled jejunal flap. Esophagus, 12(1)：57-64, 2015
• 15.Shigeyasu K, Nagasaka T, Mori Y, Yokomichi N, Kawai T, Fuji T, Kimura K, Umeda Y, Kagawa S, Goel A, Fujiwara T：Clinical Significance of MLH1 Methylation and CpG Island Methylator Phenotype as Prognostic Markers in Patients with Gastric Cancer. PLoS One, 10(6)：e0130409, 2015
• 16.Yano S, Miwa S, Kishimoto H, Uehara F, Tazawa H, Toneri M, Hiroshima Y, Yamamoto M, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM： Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma. Oncotarget, 6(15)：13133-13148, 2015
• 17.Miwa S, Yano S, Kimura H, Yamamoto M, Toneri M, Murakami T, Hayashi K, Yamamoto N, Fujiwara T, Tsuchiya H, Hoffman RM：Heterogeneous cell-cycle behavior in response to UVB irradiation by a population of single cancer cells visualized by time-lapse FUCCI imaging. Cell Cycle, 14(12)：1932-1937, 2015
• 18.Yano S, Miwa S, Kishimoto H, Toneri M, Hiroshima Y, Yamamoto M, Bouvet M, Urata Y, Tazawa H, Kagawa S, Fujiwara T, Hoffman RM：Experimental Curative Fluorescence-guided Surgery of Highly Invasive Glioblastoma Multiforme Selectively Labeled With a Killer-reporter Adenovirus. Mol Ther, 23(7)：1182-1188, 2015
• 19.Yano S, Miwa S, Mii S, Hiroshima Y, Uehara F, Kishimoto H, Tazawa H, Zhao M, Bouvet M, Fujiwara T, Hoffman RM：Cancer cells mimic in vivo spatial-temporal cell-cycle phase distribution and chemosensitivity in 3-dimensional Gelfoam® histoculture but not 2-dimensional culture as visualized with real-time FUCCI imaging. Cell Cycle, 14(6)：808-819, 2015
• 20.Miwa S, Yano S, Kimura H, Yamamoto M, Toneri M, Matsumoto Y, Uehara F, Hiroshima Y, Murakami T, Hayashi K, Yamamoto N, Bouvet M, Fujiwara T, Tsuchiya H, Hoffman RM：Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging. Cell Cycle, 14(4)：621-629, 2015
• 21.Matsui Y, Hiraki T, Gobara H, Iguchi T, Fujiwara H, Nagasaka T, Toyooka S, Kanazawa S ：Long-term survival following percutaneous radiofrequency ablation of colorectal lung metastases. J Vasc Interv Radiol,26(3)：303-310, 2015
• 22.Takaki A, Yasunaka T, Yagi T：Molecular Mechanisms to Control Post-Transplantation Hepatitis B Recurrence. Int J Mol Sci, 16(8)：17494-17513, 2015
• 23.Kanamitsu K, Washio K, Oda M, Noda T, Oyama T, Tanimoto T, Tanaka T, Ida K, Shimada A：Suspected early onset of congenital Langerhans cell histiocytosis involving ectopic cervical thymus and mediastinal thymus, simultaneously. Pediatr Blood Cancer, 62(8)：1491-1492, 2015
• 24.Yano S, Hiroshima Y, Maawy A, Kishimoto H, Suetsugu A, Miwa S, Toneri M, Yamamoto M, Katz MH, Fleming JB, Urata Y, Tazawa H, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM：Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery. Cancer Gene Therapy, 22(7)：344-350, 2015
• 25.Yano S, Zhang Y, Miwa S, Kishimoto H, Urata Y, Bouvet M, Kagawa S, Fujiwara T, Hoffman RM ：Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus. BMJ Open Respir Res, ：doi: 10.1136/bmjresp-2015-000096, 2015
• 26.Yano S, Miwa S, Kishimoto H, Urata Y, Tazawa H, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM:Eradication of osteosarcoma by fluorescence-guided surgery with tumor labeling by a killer-reporter adenovirus. J Orthop Res, ：doi: 10.1002/jor.23073, 2015
• 27.Shirakawa Y, Noma K, Ohara T, Kashima H, Maeda N, Tanabe S, Kagawa S, Fujiwara T：Prone-position thoracoscopic ligation of the thoracic duct for chyle leak following radical neck dissection in a patient with a right aortic arch. Acta Medica Okayama, 69(3)：173-176, 2015
• 28.Takehara K, Tazawa H, Okada N, Hashimoto Y, Kikuchi S, Kuroda S, Kishimoto H, Shirakawa Y, Narii N, Mizuguchi H, Urata Y, Kagawa S, Fujiwara T：Targeted Photodynamic Virotherapy Armed with a Genetically Encoded Photosensitizer. Mol Cancer Ther, DOI: 10.1158/1535-7163, 2015
• 29.Terao M, Takaki A, Maruyama T, Oe H, Yasunaka T, Tamaki N, Nakamura K, Tomofuji T, Yagi T, Sadamori H, Umeda Y, Shinoura S, Yoshida R, Nouso K, Ekuni D, Koike K, Ikeda F, Shiraha H, Morita M, Ito H, Fujiwara T, Yamamoto K：Serum Oxidative/anti-oxidative Stress Balance Is Dysregulated in Potentially Pulmonary Hypertensive Patients with Liver Cirrhosis: A Case Control study. Intern Med, 54(22)：2815-2826, 2015
• 30.Iwamoto T, Kelly C, Mizoo T, Nogami T, Motoki T, Shien T, Taira N, Hayashi N, Niikura N, Fujiwara T, Doihara H, Matsuoka J：Relative Prognostic and Predictive Value of Gene Signature and Histologic Grade in Estrogen Receptor–Positive, HER2-Negative Breast Cancer. Clin Breast Cancer, doi: 10.1016/j.clbc.2015.10.004, 2015
• 31.Sugiu K, Iwamoto T, Kelly CM, Watanabe N, Motoki T, Itoh M, Ohtani S, Higaki K, Imada T, Yuasa T, Omori M, Sonobe H, Fujiwara T, Matsuoka J ：Neoadjuvant Chemotherapy with or without Concurrent Hormone Therapy in Estrogen Receptor-Positive Breast Cancer:NACED-Randomized Multicenter Phase II Trial. Acta Medica Okayama, 69(5)：291-299, 2015
• 32.Inada R, Nagasaka T, Kondo Y, Watanabe A, Toshima T, Kubota N, Kikuchi S, Ishida M, Kuroda S, Mori Y, Kishimoto H, Fujiwara T：A Case-matched Comparative Study of Laparoscopic and Open Total Proctocolectomy for Ulcerative Colitis. Acta Medica Okayama, 69(5)：267-273, 2015
• 33.Tazawa H, Nagasaka T, Kagawa S, Fujiwara T：MicroRNA as a molecular target for gastrointestinal cancers. Transl Gastrointest Cancer, 4(3)：219-235, 2015
• 34.Wada S, Matsushita Y, Tazawa H, Aoi W, Naito Y, Higashi A, Ohshima H, Yoshikawa T：Loss of p53 in stromal fibroblasts enhances tumor cell proliferation through nitric-oxide-mediated cyclooxygenase 2 activation. Free Radic Res, 49(3)：269-278, 2015
• 35.Callari M, Cappelletti V, D'Aiuto F, Musella V, Lembo A, Petel F, Karn T, Iwamoto T, Provero P, Daidone MG, Gianni L, Bianchini G：Subtype specific metagene-based prediction of outcome after neoadjuvant and adjuvant treatment in breast cancer. Clin Cancer Res, ：doi:10.1158/1078-0432.CCR-15-0757, 2015
• 36.Kondo T, Hayashi N, Ohde S, Suzuki K, Yoshida A, Yagata H, Niikura N, Iwamoto T, Kida K, Murai M, Takahashi Y, Tsunoda H, Nakamura S, Yamauchi H ： A model to predict upstaging to invasive carcinoma in patients preoperatively diagnosed with ductal carcinoma in situ of the breast. J Surg Oncol, 112(5)：476-480, 2015
• 37.Kinoshita T, Fukui N, Anan K, Iwamoto T, Niikura N, Kawai M, Hayashi N, Tsugawa K, Aogi K, Ishida T, Masuoka H, Masuda S, Iijima K, Nakamura S, Tokuda Y：Comprehensive prognostic report of the Japanese Breast Cancer Society Registry in 2004. Breast Cancer,
  DOI 10.1007/s12282-015-0644-5, 2015
• 38.Anan K, Fukui N, Kinoshita T, Iwamoto T, Niikura N, Kawai M, Hayashi N, Tsugawa K, Aogi K, Ishida T, Masuoka H, Masuda S, Iijima K, Nakamura S, Tokuda Y：Comprehensive prognostic report of the Japanese Breast Cancer Society Registry in 2005. Breast Cancer,
  DOI 10.1007/s12282-015-0645-4, 2015
• 39.Iwamoto T, Fukui N, Kinoshita T, Anan K, Niikura N, Kawai M, Hayashi N, Tsugawa K, Aogi K, Ishida T, Masuoka H, Masuda S, Iijima K, Nakamura S, Tokuda Y：Comprehensive prognostic report of the Japanese Breast Cancer Society registry in 2006. Breast Cancer,
  DOI 10.1007/s12282-015-0646-3, 2015
• 40.Yano S, Takehara K, Kishimoto H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM: Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models. Oncotarget, doi: 10.18632/oncotarget.6670, 2015
• 41.Fujiwara T, Kagawa S, Tazawa H:Multidisciplinary Cancer Therapy with Telomerase-Specific Oncolytic Adenovirus. Current Cancer Therapy Reviews,11(3):178-187, 2015
• 42.Kuwada K, Kuroda S, Kikuchi S, Hori N, Kubota T, Nishizaki M, Kagawa S, Fujiwara T: Strategic approach to concurrent aberrant left gastric vein and aberrant left hepatic artery in laparoscopic distal gastrectomy for early gastric cancer: A case report. Asian J Endosc Surg, 8(4):454-456, 2015
• 43.Niikura N, Hashimoto J, Kazama T, Koizumi J, Ogiya R, Terao M, Oshitanai R, Morioka T, Tsuda B, Okamura T, Saito Y, Iwaisako K, Iwamoto T, Hayashi N, Imai Y, Tokuda Y: Diagnostic performance of F-fluorodeoxyglucose PET/CT and bone scintigraphy in breast cancer patients with suspected bone metastasis. Breast cancer, DOI 10.1007/s12282-015-0621-z, 2015
• 44.Inagaki Y, Oshiro Y, Tanaka T, Yoshizumi T, Okajima H, Ishiyama K, Nakanishi C, Hidaka M, Wada H, Hibi T, Takagi K, Honda M, Kuramitsu K, Tanaka H, Tohyama T, Ikegami T, Imura S, Shimamura T, Nakayama Y, Urahashi T, Yamagishi K, Ohnishi H, Nagashima S, Takahashi M, Shirabe K, Kokudo N, Okamoto H, Ohkohchi N:A Nationwide Survey of Hepatitis E Virus Infection and Chronic Hepatitis E in Liver Transplant Recipients in Japan. EBioMedicine, 2(11):1607-1612, 2015
• 45.Shibata M, Matsusaki T, Kaku R, Umeda Y, Yagi T, Morimatsu H:Intraoperative Oxygen Consumption During Liver Transplantation. Transplant Proc, 47(10):2902-2906, 2015

2014年

• 1.Kikuchi S, Kishimoto H, Tazawa H, Hashimoto Y, Kuroda S, Nishizaki M, Nagasaka T, Shirakawa Y, Kagawa S, Urata Y, Hoffman RM, Fujiwara T：Biological Ablation of Sentinel Lymph Node Metastasis in Submucosally Invaded Early Gastrointestinal Cancer. Mol Ther, doi: 10.1038/mt.2014.244, 2014
• 2.Kuise T, Noguchi H, Tazawa H, Kawai T, Iwamuro M, Saitoh I, Kataoka H, Watanabe M, Noguchi Y, Fujiwara T：Establishment of a pancreatic stem cell line from fibroblast-derived induced pluripotent stem cells. BioMedical Engineering OnLine, 13:64, doi:10.1186/1475-925X-13-64, 2014
• 3.Nakamura K, Joja I, Nagasaka T, Haruma T, Hiramatsu Y：Maximum standardized lymph node uptake value could be an important predictor of recurrence and survival in patients with cervical cancer. Eur J Obstet Gynecol Reprod Biol, 173:77-82, 2014
• 4.Link A, Balaguer F, Nagasaka T, Boland CR, Goel A：MicroRNA miR-J1-5p as a potential Biomarker for JC Virus Infection in the Gastrointestinal Tract. PLoS One, DOI: 10.1371/journal.pone.0100036, 2014
• 5.Kondo Y, Nagasaka T, Kobayashi S, Kobayashi N, Fujiwara T：Management of peritoneal effusion by sealing with a self-assembling nanofiber polypeptide following pelvic surgery. Hepatogastroenterology, 61(130):349-353, 2014
• 6.Shigeyasu K, Tazawa H, Hashimoto Y, Mori Y, Nishizaki M, Kishimoto H, Nagasaka T, Kuroda S, Urata Y, Goel A, Kagawa S, Fujiwara T：Fluorescence virus-guided capturing system of human colorectal circulating tumour cells for non-invasive companion diagnostics. Gut, doi: 10.1136/gutjnl-2014-306957, 2014
• 7.Eto K, Nishimura W, Oishi H, Udagawa H, Kawaguchi M, Hiramoto M, Fujiwara T, Takahashi S, Yasuda K：MafA is required for postnatal proliferation of pancreatic β-cells. PLoS One, 9(8):e104184, 2014
• 8.Shirakawa Y, Noma K, Maeda N, Katsube R, Tanabe S, Ohara T, Sakurama K, Fujiwara T：Assistant-based standardization of prone position thoracoscopic esophagectomy. Acta Medica Okayama, 68(2):111-117, 2014
• 9.Kuroda S, Kubota T, Aoyama K, Kikuchi S, Tazawa H, Nishizaki M, Kagawa S, Fujiwara T：Establishment of a Non-invasive Semi-Quantitative Bioluminescent Imaging Method for Monitoring of an Orthotopic Esophageal Cancer Mouse Model. PLoS One, 9(12): e114562, 2014
• 10.Inada R, Yamamoto S, Oshiro T, Takawa M, Fujita S, Akasu T：A case-matched comparison of the short-term outcomes between laparoscopic and open abdominoperineal resection for rectal cancer. Surgery Today, 44:640-645, 2014
• 11.Inada R, Yamamoto S, Takawa M, Fujita S, Akasu T：Laparoscopic resection of synchronous colorectal cancers in separate specimens. Asian J Endosc Surg, 7:227-231, 2014
• 12.Tsutsumi K, Kato H, Okada H, Yagi T, Yamamoto K：Transplanted liver graft ischemia caused by pediatric ERCP in the prone position. Endoscopy, DOI: 10.1055/s-0034-1390732, 2014
• 13.Tsuzakia R, Takakia A, Yagi T, Ikeda F, Koike K, Iwasaki Y, Shiraha H, Miyake Y, Sadamori H, Shinoura S, Umeda Y, Yoshida R, Nobuoka D, Utsumi M, Nakayama E, Fujiwara T, Yamamoto K：Hepatitis C virus-specific t-cell response correlates with hepatitis activity and donor IL28B genotype early after liver transplantation. Acta Medica Okayama, 68(5):291-302, 2014
• 14.Takaki A, Yagi T, Yamamoto K：Contradictory immune response in post liver transplantation hepatitis B and C. International Journal of Inflammation, doi: 10.1155/2014/814760, 2014
• 15.Utsumi M, Takaki A, Umeda Y, Koike K, Napier SC, Watanabe N, Sadamori H, Shinoura S, Yoshida R, Nobuoka D, Yasunaka T, Nakayama E, Yamamoto K, Fujiwara T, Yagi T：Frequency of regulatory T-cell and hepatitis C viral antigen-specific immune response in recurrent hepatitis C after liver transplantation. Transplant Immunology, 31(1):33-41, 2014
• 16.Uchida D, Shiraha H, Kato H, Nagahara T, Iwamuro M, Kataoka J, Horiguchi S, Watanabe M, Takaki A, Nouso K, Nasu Y, Yagi T, Kumon H, Yamamoto K：Potential of adenovirus-mediated REIC/Dkk-3 gene therapy for use in the treatment of pancreatic cancer. Journal of Gastroenterology and Hepatology, 29(5):973-983, 2014
• 17.Yano S, Miwa S, Mii S, Hiroshima Y, Uehara F, Yamamoto M, Kishimoto H, Tazawa H, Fujiwara T, Hoffman RM：Invading cancer cells are predominantly in G 0/G 1 resulting in chemoresistance demonstrated by real-time FUCCI imaging. Cell Cycle, 13(6):953-960, 2014
• 18.Itoh M, Iwamoto T, Matsuoka J, Nogami, T, Motoki T, Shien T, Taira N, Niikura N, Hayashi N, Ohtani S, Higaki K, Fujiwara T, Doihara H, Symmans WF, Pusztai L：Estrogen receptor (ER) mRNA expression and molecular subtype distribution in ER-negative/progesterone receptor-positive breast cancers. Breast Cancer Res Treat, 143:403-409, 2014
• 19.Yano S, Zhang Y, Miwa S, Tome Y, Hiroshima Y, Uehara F, Yamamoto M, Suetsugu A, Kishimoto H, Tazawa H, Zhao M, Bouvet M, Fujiwara T, Hoffman RM：Spatial-temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness. Cell Cycle, 13(13):2110-2119, 2014
• 20.Yano S, Li S, Han Q, Tan Y, Bouvet M, Fujiwara T, Hoffman RM：Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity. Oncotarget, 5(18):8729-8736, 2014
• 21.Utsumi M, Sadamori H, Shinoura S, Umeda Y, Yoshida R, Nobuoka D, Takagi K, Fujiwara T, Yagi T：Risk factors of morbidity and predictors of long-term survival after hepatopancreatoduodenectomy for biliary cancer. Hepatogastroenterology, 61(136):2167-2172, 2014
• 22.Kanda Y, Kawaguchi T, Kuramitsu Y, Kitagawa T, Kobayashi T, Takahashi N, Tazawa H, Habelhah H, Hamada JI, Kobayashi M, Hirahata M, Onuma K, Osaki M, Nakamura K, Kitagawa T, Hosokawa M, Okada F：Fascin regulates chronic inflammation-related human colon carcinogenesis by inhibiting cell anoikis. Proteomics, 14(9):1031-1041, 2014
• 23.Nobuoka D, Fuji T, Yoshida K, Takagi K, Kuise T, Utsumi M, Yoshida R, Umeda Y, Shinoura S, Takeda Y, Ohtsuka A：Surgical education using a multi-viewpoint and multi-layer three-dimensional atlas of surgical anatomy (with video). Journal of Hepato-Biliary Pancreatic Sciences, 21(8):556-561, 2014
• 24.Yabusaki M, Sato J, Kohyama A, Kojima T, Nobuoka D, Yoshikawa T, Sawada Y, Murakami K, Gohda K, Okegawa T, Nakamura M, Takamatsu K, Ito M, Kaneko K, Nakatsura T：Detection and preliminary evaluation of circulating tumor cells in the peripheral lood of patients with eight types of cancer using a telomerase-specific adenovirus. Oncology Reports, 32(5):1772-1778, 2014
• 25.Yagi T, Nobuoka D, Shinoura S, Umeda Y, Sato D, Yoshida R, Utsumi M, Fuji T, Sadamori H, Fujiwara T：First successful case of simultaneous liver and kidney transplantation for patients with chronic liver and renal failure in Japan. Hepatology Research, 44(3): 358-363, 2014
• 26.Niikura N, Sakatani T, Arima N, Ohi Y, Honma N, Kanomata N, Yoshida K, Kadoya T, Tamaki K, Kumaki N, Iwamoto T, Sugie T, Moriya T：Assessment of the Ki67 labeling index: a Japanese validation ring study. Breast Cancer, DOI 10.1007/s12282-014-0536-0, 2014
• 27.Niikura N, Masuda S, Kumaki N, Xiaoyan T, Terada M, Terao M, Iwamoto T, Oshitanai R, Morioka T, Tuda B, Okamura T, Saito Y, Suzuki Y, Tokuda Y：Prognostic significance of the ki67 scoring categories in breast cancer subgroups. Clin Breast Cancer, 14(5): 323-329, 2014
• 28.Gyorffy B, Bottai G, Lehmann-Che J, Keri G, Orfi L, Iwamoto T, Desmedt C, Bianchini G, Turner NC, de The H, Andre F, Sotiriou C, Hortobagyi GN, Di Leo A, Pusztai L, Santarpia L：TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers. Mol Oncol, 8(3): 508-519, 2014
• 29.Bertucci F, Ueno NT, Finetti P, Vermeulen P, Lucci A, Robertson FM, Marsan M, Iwamoto T, Krishnamurthy S, Masuda H, Van Dam P, Woodward WA, Cristofanilli M, Reuben JM, Dirix L, Viens P, Symmans WF, Birnbaum D, Van Laere SJ：Gene expression profiles of inflammatory breast cancer: correlation with response to neoadjuvant chemotherapy and metastasis-free survival. Ann Oncol, 25(2): 358-365, 2014
• 30.Kai K, Iwamoto T, Kobayashi T, Arima Y, Takamoto Y, Ohnishi N, Bartholomeusz C, Horii R, Akiyama F, Hortobagyi GN, Pusztai L, Saya H, Ueno NT：Ink4a/Arf(-/-) and HRAS(G12V) transform mouse mammary cells into triple-negative breast cancer containing tumorigenic CD49f(-) quiescent cells. Oncogene, 33(4): 440-448, 2014
• 31.Masuda H, Brewer TM, Liu DD, Iwamoto T, Shen Y, Hsu L, Willey JS, Gonzalez-Angulo AM, Chavez-MacGregor M, Fouad TM, Woodward WA, Reuben JM, Valero V, Alvarez RH, Hortobagyi GN, Ueno NT：Long-term treatment efficacy in primary inflammatory breast cancer by hormonal receptor- and HER2-defined subtypes. Ann Oncol, 25(2): 384-391, 2014
• 32.Inada R, Nagasaka T, Toshima T, Mori Y, Kondo Y, Kishimoto H, Fujiwara T：Intussusception due to rectal adenocarcinoma in a young adult: A case report. World J Gastroenterol, 20(35):12678-12681, 2014
• 33.Shigeyasu K, Tanakaya K, Nagasaka T, Aoki H, Fujiwara T, Sugano K, Ishikawa H, Yoshida T, Moriya Y, Furukawa Y, Goel A, Takeuchi H：Early detection of metachronous bile duct cancer in Lynch syndrome: report of a case. Surg Today, 44(10): 1975-1981, 2014
• 34.Kagawa S, Shigeyasu K, Ishida M, Watanabe M, Tazawa H, Nagasaka T, Shirakawa Y, Fujiwara T：Molecular diagnosis and therapy for occult peritoneal metastasis in gastric cancer patients. World J Gastroenterol, 20(47):17796-17803, 2014
• 35.Itokawa F, Kamisawa T, Nakano T, Itoi T, Ha mada Y, Ando H, Fujii H, Koshinaga T, Yoshida H, Tamoto E, Noda T, Kimura Y, Maguchi J, Urushihara N, Horaguchi J, Morotomi Y, Sato M, Hanada K, Tanaka M, Takahashi A, Yamaguchi T, Arai Y, Horiguchi A, Igarashi Y, Inui K：Exploring the length of the common channel of pancreaticobiliary maljunction on magnetic resonance cholangiopancreatography. J Hepatobiliary Pancreat Sci, DOI:10.1002/jhbp.168, 2014
• 36.Kuroda S, Tam J, Roth JA, Sokolov K, Ramesh R：EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage. Int J Nanomedicine, 9：3825-3839, 2014

2013年

• 1.Sadamori H, Umeda Y, Yagi T, Fujiwara T：The Modulation of Portal Venous Hemodynamics in Living Donor Liver.Hemodynamics: Monitoring, Theory and Applications(Senzaki H),pp217-229,Nova science publishers, Inc. New York, 2013（著書）
• 2.Kagawa S, Fujiwara T：Gene therapy for cancer treatment.Gene Therapy: Technologies & Applications（Morishita R, Nakagami H,）, pp70-83, Future Medicine Ltd, London, 2013（著書）
• 3.Kuroda S, Kagawa S, Fujiwara T：Selectively replicating oncolytic adenoviruses combined with chemotherapy, radiotherapy, or molecular targeted therapy for treatment of human cancers. Gene Therapy of Cancer, 3rd Edition (Lattime, E. C., Gerson, S. L., ed.), pp171-183, Academic Press, 2013（著書）
• 4.Tazawa H, Kagawa S, Fujiwara T：Application of cancer gene therapy using tumor suppressor gene p53. Tumor Suppressor Genes: Functions, Regulation and Health Effects (Gunduz M, Gunduz E), pp81-103, Nova science publishers, Inc., New York, 2013（著書）
• 5.Sadamori H, Yagi T, Shinoura S, Umeda Y, Yoshida R, Satoh D, Nobuoka D, Utsumi M, Yoshida K, Fujiwara T：Bloodless donor hepatectomy in living donor liver transplantation: counterclockwise liver rotation and early hanging maneuver.J Gastrointest Surg,17(1):203-206, 2013
• 6.Sadamori H, Yagi T, Shinoura S, Umeda Y, Yoshida R, Satoh D, Nobuoka D, Utsumi M, Fujiwara T：New surgical approach to large splenorenal shunt in living donor liver transplantation: diversion of SMV and SPV blood flow. J　Gastrointest Surg,17(2)：403-407, 2013
• 7.Sasaki T, Tazawa H, Hasei J, Osaki S, Kunisada T, Yoshida A, Hashimoto Y, Yano S, Yoshida R, Kagawa S, Uno F, Urata Y, Ozaki T, Fujiwara T： A　simple detection system for adenovirus receptor expression using a telomerase-specific replication-competent adenovirus. Gene Ther,20(1)：112-118, 2013
• 8.Sadamori H, Yagi T, Shinoura S, Umeda Y, Yoshida R, Satoh D, Nobuoka D, Utsumi M, Fujiwara T：Risk factors for major morbidity after liver resection for hepatocellular carcinoma.　Br J Surg,100(1)：122-129, 2013
• 9.Sadamori H, Yagi T, Shinoura S, Umeda Y, Yoshida R, Satoh D, Nobuoka D, Utsumi M, Yoshida K, Fujiwara T：Risk factors for organ/space surgical site infection after hepatectomy for hepatocellular carcinoma in 359 recent cases.J Hepatobiliary Pancreat Sci,20(2)：186-196, 2013
• 10.Umeda Y, Nagasaka T, Mori Y, Sadamori H, Sun DS, Shinoura S, Yoshida R, Satoh D, Nobuoka D, Utsumi M, Yoshida K, Yagi T, Fujiwara T：Poor prognosis of KRAS or BRAF mutant colorectal liver metastasis without microsatellite instability.J Hepatobiliary Pancreat Sci,20(2)：223-233, 2013
• 11.Kohka Takahashi H, Sadamori H, Liu K, Wake H, Mori S, Yoshino T, Yamamoto Y, Yamamoto H, Nishibori M：Role of cell-cell interactions in high mobility group box 1 cytokine activity in human peripheral blood mononuclear cells and mouse splenocytes.Eur J Pharmacol,701：194–202, 2013
• 12.Bao XH, Takaoka M, Hao HF, Fukazawa T, Yamatsuji T, Sakurama K, Takigawa N, Nakajima M, Fujiwara T, Naomoto Y： Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer.Oncol Rep,29(1)：45-50, 2013
• 13.Shigeyasu K, Kagawa S, Uno F, Nishizaki M, Kishimoto H, Gochi A, Kimura T, Takahata T, Nonaka Y, Ninomiya M, Fujiwara T：Multicenter phase II study of S-1 and docetaxel combination　chemotherapy for advanced or recurrent gastric cancer patients with peritoneal dissemination.Cancer Chemother Pharmacol,71(4)：937-943, 2013
• 14.Nishikawa T, Takaoka M, Ohara T, Tomono Y, Hao H, Bao X, Fukazawa T, Wang Z, Sakurama K, Fujiwara Y, Motoki T, Shirakawa Y, Yamatsuji T, Tanaka N, Fujiwara T, Naomoto Y：Antiproliferative effect of a novel mTOR inhibitor temsirolimus contributes to the prolonged survival of orthotopic esophageal cancer-bearing mice.Cancer Biol Ther,14(3)：230-236, 2013
• 15.Hasei J, Sasaki T, Tazawa H, Osaki S, Yamakawa Y, Kunisada T, Yoshida A, Hashimoto Y, Onishi T, Uno F, Kagawa S, Urata Y, Ozaki T, Fujiwara T：Dual programmed cell death pathways induced by p53 transactivation overcome resistance to oncolytic adenovirus in human osteosarcoma cells.Mol Cancer Ther,12(3)：314-325, 2013
• 16.Nobuoka D, Yoshikawa T, Takahashi M, Iwama T, Horie K, Shimomura M, Suzuki S, Sakemura N, Nakatsugawa M, Sadamori H, Yagi T, Fujiwara T, Nakatsura T：Intratumoral peptide injection enhances tumor cell antigenicity recognized by cytotoxic T lymphocytes: a potential option for improvement in antigen-specific cancer immunother．Cancer Immunol Immunother,62(4)：639-652, 2013
• 17.Ohara T, Noma K, Urano S, Watanabe S, Nishitani S, Tomono Y, Kimura F, Kagawa S, Shirakawa Y, Fujiwara T：A novel synergistic effect of iron depletion on antiangiogenic cancer therapy．Int J Cancer,132(11)：2705-2713, 2013
• 18.Yagi T, Nobuoka D, Shinoura S, Umeda Y, Sato D, Yoshida R, Utsumi M, Fuji T, Sadamori H, Fujiwara T：First successful case of simultaneous liver and kidney transplantation for patients with chronic liver and renal failure in Japan．Hepatol Res,2013
• 19.Utsumi M, Umeda Y, Sadamori H, Nagasaka T, Takaki A, Matsuda H, Shinoura S, Yoshida R, Nobuoka D, Satoh D, Fuji T, Yagi T, Fujiwara T：Risk factors for acute renal injury in living donor liver transplantation: evaluation of the RIFLE criteria．Transpl Int,26(8)：842-852, 2013
• 20.Satoh D, Yagi T, Nagasaka T, Shinoura S, Umeda Y, Yoshida R, Utsumi M, Tanaka T, Sadamori H, Fujiwara T：CD14 upregulation as a distinct feature of non-alcoholic fatty liver disease after pancreatoduodenectomy．World J Hepatol,5(4)：189-195, 2013
• 21.Takaki A, Yagi T, Yasunaka T, Sadamori H, Shinoura S, Umeda Y, Yoshida R, Sato D, Nobuoka D, Utsumi M, Yasuda Y, Nakayama E, Miyake Y, Ikeda F, Shiraha H, Nouso K, Fujiwara T, Yamamoto K：Which patients respond best to hepatitis B vaccination after a hepatitis B virus-related liver transplantation? J Gastroenterol,[Epub ahead of print], 2013
• 22.Nobuoka D, Yoshikawa T, Fujiwara T, Nakatsura T：Peptide intra-tumor injection for cancer immunotherapy: Enhancement of tumor cell antigenicity is a novel and attractive strategy．Hum Vaccin Immunother,9(6)：1234-1236, 2013
• 23.Sadamori H, Yagi T, Shigeyasu K, Umeda Y, Sugihara M, Yokomichi N, Ohara T, Nishida N, Nagasaka T, Goel A, Fujiwara T：Advanced hepatocellular carcinoma with lymph node metastases showing epithelial to mesenchymal transition effectively treated with systemic chemotherapy: Report of a case.Hepatol Res,[Epub ahead of print], 2013
• 24.Tanabe S, Shirakawa Y, Takehara Y, Maeda N, Katsube R, Ohara T, Sakurama K, Noma K, Fujiwara T：Successfully treated pneumatosis cystoides intestinalis with pneumoperitoneum onset in a patient administered α-glucosidase inhibitor.Acta Med Okayama,67(2)：123-128, 2013
• 25.Sadamori H, Yagi T, Shinoura S, Umeda Y, Yoshida R, Sato D, Nobuoka D, Utsumi M, Fujiwara T：Living donor liver transplantation to a survivor of liver resection for hepatocellular carcinoma with major portal vein invasion.　Acta Med Okayama,67(2)：117-121, 2013
• 26.Alafate A, Shinya T, Okumura Y, Sato S, Hiraki T, Ishii H, Gobara H, Kato K, Fujiwara T, Miyoshi S, Kaji M, Kanazawa S：The Maximum standardized uptake value is more reliable than size measurement in early follow-up to evaluate potential pulmonary malignancies following radiofrequency ablation.Acta Med Okayama,67(2)：105-112, 2013
• 27.Li G.D, Kawashima H, Ogose A, Ariizumi T, Hotta T, Kuwano R, Urata Y, Fujiwara T, Endo N：Telomelysin shows potent antitumor activity through apoptotic and non-apoptotic cell death in soft tissue sarcoma cells.Cancer Sci,104(9)：1178-1188, 2013
• 28.Tazawa H, Kagawa S, Fujiwara T：Advances in adenovirus-mediated p53 cancer　gene therapy.Expert Opin Biol Ther,13(11)：1569-1583, 2013
• 29.Yano S, Tazawa H, Hashimoto Y, Shirakawa Y, Kuroda S, Nishizaki M, Kishimoto　H, Uno F, Nagasaka T, Urata Y, Kagawa S, Hoffman RM, Fujiwara T：A　genetically　engineered oncolytic adenovirus decoys and lethally traps quiescent cancer stem-like cells into S/G2/M-phases.Clin Cancer Res,19(23)：6495-6505, 2013
• 30.Sato D, Kurihara Y, Kondo S, Shirota T, Urata Y, Fujiwara T, Shintani S ：Antitumor effects of telomerase-specific replication-selective oncolytic viruses for adenoid cystic carcinoma cell lines.Oncol Rep, [Epub ahead of print], 2013
• 31.Nishimura W, Eto K, Miki A, Goto M, Kawaguchi M, Nammo T, Udagawa H, Hiramoto M, Shimizu Y, Okamura T, Fujiwara T, Yasuda Y, Yasuda K：Quantitative Assessment of Pdx1 Promoter Activity in Vivo Using a Secreted Luciferase Reporter System.Endocrinology,154(11)：4388-4395, 2013
• 32.Shigeyasu K, Tanakaya K, Nagasaka T, Aoki H, Fujiwara T, Sugano K, Ishikawa H, Yoshida T, Moriya Y, Furukawa Y, Goel A, Takeuchi H：Early detection of metachronous bile duct cancer in Lynch syndrome: report of a case.Surg Today,2013 Jul 31. [Epub ahead of print], 2013
• 33.Miwa S, Yano S, Tome Y, Sugimoto N, Hiroshima Y, Uehara F, Mii S, Kimura H, Hayashi K, Efimova EV, Fujiwara T, Tsuchiya H, Hoffman RM：Dynamic color-coded　fluorescence imaging of the cell-cycle phase, mitosis, and apoptosis demonstrates　how caffeine modulates cisplatinum efficacy.J Cell Biochem,114(11)：2454-2460, 2013
• 34.Oishi K, Miyamoto Y, Saito H, Murase K, Ono K, Sawada M, Watanabe M, Noguchi Y, Fujiwara T, Hayashi S, Noguchi H：In vivo imaging of transplanted islets labeled with a novel cationic nanoparticle.　PLoS One,8(2)：e57046, 2013
• 35.Nobuoka D, Yoshikawa T, Sawada Y, Fujiwara T, Nakatsura T：Peptide vaccines for hepatocellular carcinoma.　Hum Vaccin Immunother,9(2)：210-222, 2013
• 36.Lin WH, Yeh SH, Yang WJ, Yeh KH, Fujiwara T, Nii A, Chang SS, Chen PJ：Telomerase-specific oncolytic adenoviral therapy for orthotopic hepatocellular carcinoma in HBx transgenic mice.Int J Cancer,132(6)：1451-1462, 2013
• 37.Fujiwara Y, Yamada T, Naomoto Y, Yamatsuji T, Shirakawa Y, Tanabe S, Noma K, Kimura T, Aoki H, Matsukawa H, Kimura M, Nonaka Y, Sasaki H, Onoda T, Otawa Y, Takaoka M, Fukazawa T, Ohno Y, Fujiwara T：Multicentred surgical site infection surveillance using partitioning analysis.J Hosp Infect. ,85：282-288, 2013
• 38.Kishimoto H, Momiyama M, Aki R, Kimura H, Suetsugu A, Bouvet M, Fujiwara T, Hoffman RM：Development of a clinically-precise mouse model of rectal cancer.　PLoS One,8(11)：e79453, 2013
• 39.Tazawa H, Kagawa S, Fujiwara T：Oncolytic Adenovirus-Induced Autophagy: Tumor-Suppressive Effect and Molecular Basis.Acta Med Okayama,　67(6)：333-342, 2013
• 40.Matsumoto K, Miyake Y, Umeda Y, Matsushita H, Matsuda H, Takaki A, Sadamori H, Nouso K, Yagi T, Fujiwara, T, Yamamoto K：Serial changes of serum growth factor levels and liver regeneration after partial hepatectomy in healthy humans.Int. J. Mol. Sci.,14：20877-20889, 2013
• 41.Itoh M, Iwamoto T, Matsuoka J, Nogami T, Motoki T, Shien T, Taira N, Niikura N, Hayashi N, Ohtani S, Higaki K, Fujiwara T, Doihara H, Symmans, W. F, Puszta, L ：Estrogen receptor (ER) mRNA expression and molecular subtype distribution in ER-negative/progesterone receptor-positive breast cancers.　Breast Cancer Res Treat(in press), 2013
• 42.Ohara T, Shirakawa Y, Noma K, Maeda N, Katsube R, Tanabe S, Fujiwara T：Direct observation diverticulectomy for Zenker’s diverticulum carcinoma. Esophagus,10：235–238, 2013
• 43.Inada R, Yamamoto S, Oshiro T, Takawa M, Fujita S, Akasu T：A case-matched comparison of the short-term outcomes between laparoscopic and open abdominoperineal resection for rectal cancer.Surgery today, (in press), 2013
• 44.Tazawa H, Kawaguchi T, Kobayashi T, Kuramitsu Y, Wada S, Satomi Y, Nishino H, Kobayashi M, Kanda Y, Tanaka H, Osaki M, Kitagawa T, Hosokawa M, Okada F：Chronic inflammation-derived nitric oxide converts human colonic adenoma cells into adenocarcinoma cells.Exp Cell Res,319(18)：2835-2844, 2013
• 45.Masuda H, Brewer TM, Liu DD, Iwamoto T, Shen Y, Hsu L, Willey JS, Gonzalez-Angulo AM, Chavez-Macgregor M, Fouad TM, Woodward WA, Reuben JM, Valero V, Alvarez RH, Hortobagyi GN, Ueno NT.： Long-term treatment efficacy in primary inflammatory breast cancer by hormonal receptor- and HER2-defined subtypes.Ann Oncol,25(2)：384-391, 2013
• 46.Itoh M, Iwamoto T, Matsuoka J, Nogami T, Motoki T, Shien T, Taira N, Niikura N, Hayashi N, Ohtani S, Higaki K, Fujiwara T, Doihara H, Symmans WF, Pusztai L：Estrogen receptor (ER) mRNA expression and molecular subtype distribution in ER-negative/progesterone receptor-positive breast cancers.Breast Cancer Res Treat,143(2)：403-409, 2013
• 47.Bertucci F, Ueno NT, Finetti P, Vermeulen P, Lucci A, Robertson FM, Marsan M, Iwamoto T, Krishnamurthy S, Masuda H, Van Dam P, Woodward WA, Cristofanilli M, Reuben JM, Dirix L, Viens P, Symmans WF, Birnbaum D, Van Laere SJ. ：Gene expression profiles of inflammatory breast cancer: correlation with response to neoadjuvant chemotherapy and metastasis-free survival.　Ann Oncol,25(2)：358-365, 2013
• 48.Masuda H, Baggerly KA, Wang Y, Iwamoto T, Brewer T, Pusztai L, Kai K, Kogawa T, Finetti P, Birnbaum D, Dirix L, Woodward WA, Reuben JM, Krishnamurthy S, Symmans WF, Van Laere SJ, Bertucci F, Hortobagyi GN, Ueno NT：Comparison of molecular subtype distribution in triple-negative inflammatory and non-inflammatory breast cancers. Breast Cancer Res,15(6)：R112, 2013
• 49.Delpech Y, Coutant C, Hsu L, Barranger E, Iwamoto T, Barcenas CH, Hortobagyi GN, Rouzier R, Esteva FJ, Pusztai L：Clinical benefit from neoadjuvant chemotherapy in oestrogen receptor-positive invasive ductal and lobular carcinomas. Br　J Cancer,108(2)：285-291, 2013
• 50.Kai K, Iwamoto T, Kobayashi T, Arima Y, Takamoto Y, Ohnishi N, Bartholomeusz C, Horii R, Akiyama F, Hortobagyi GN, Pusztai L, Saya H, Ueno NT：Ink4a/Arf(-/-) and HRAS(G12V) transform mouse mammary cells into triple-negative breast cancer containing tumorigenic CD49f(-) quiescent cells.Oncogene,23(33)：440-448, 2013
• 51.Van Laere SJ, Ueno NT, Finetti P, Vermeulen PB, Lucci A, Robertson FM, Marsan M, Iwamoto T, Krishnamurthy S, Masuda H, Van Dam PA, Woodward WA, Viens P, Cristofanilli M, Birnbaum D, Dirix LY, Reuben JM, Bertucci F：Uncovering the molecular secrets of Inflammatory Breast Cancer biology: An integrated analysis of three distinct Affymetrix gene expression data sets.Clin Cancer Res,1(19)：4685-4696, 2013
• 52.Szekely B, Iwamoto T, Szasz AM, Qi Y, Matsuoka J, Symmans WF, Tokes AM, Kulka J, Swanton C, Pusztai L：A 3-gene proliferation score (TOP-FOX-67) can re-classify histological grade-2, ER-positive breast cancers into low- and high-risk prognostic categories.Breast Cancer Res Treat,138(3)：691-698, 2013
• 53.Brewer TM, Masuda H, Liu DD, Shen Y, Liu P, Iwamoto T, Kai K, Barnett CM, Woodward WA, Reuben JM, Yang P, Hortobagyi GN, Ueno NT：Statin use in primary inflammatory breast cancer: a cohort study.Br J Cancer,109(2)：318-324, 2013
• 54.Trentini F, Ji Y, Iwamoto T, Qi Y, Pusztai L, Muller P.：Bayesian Mixture Models for Assessment of Gene Differential Behaviour and Prediction of pCR through the Integration of Copy Number and Gene Expression Data. PLoS One,8(7)：e68071, 2013
• 55.Wang X, Saso H, Iwamoto T, Xia W, Gong Y, Pusztai L, Woodward WA, Reuben JM, Warner SL, Bearss DJ, Hortobagyi GN, Hung MC, Ueno NT：TIG1 Promotes the Development and Progression of Inflammatory Breast Cancer through Activation of Axl Kinase.Cancer Res,73(21)：6516-6525, 2013
• 56.Santarpia L, Iwamoto T, Di Leo A, Hayashi N, Bottai G, Stampfer M, Andre F, Turner NC, Symmans WF, Hortobagyi GN, Pusztai L, Bianchini G：DNA repair gene patterns as prognostic and predictive factors in molecular breast cancer subtypes.Oncologist,18(10)：1063-1073, 2013
• 57.Bianchini G, Pusztai L, Karn T, Iwamoto T, Rody A, Kelly CM, Muller V, Schmidt M, Qi Y, Holtrich U, Becker S, Santarpia L, Fasolo A, Del Conte G, Zambetti M, Sotiriou C, Haibe-Kains B, Symmans WF, Gianni L：Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers.Breast Cancer Res,15(5)：R86, 2013
• 58.Niikura N, Kimura M, Iwamoto T, Hayashi N, Shintoku J, Saito Y, Suzuki Y, Tokuda Y：Women prefer adjuvant endocrine therapy to chemotherapy for breast cancer treatment.Breast Cancer,20　(1)：67-74, 2013
• 59.Kuise T, Noguchi H, Saitoh I, Kataoka H, Watanabe M, Noguchi Y, Fujiwara T：Isolation Efficiency of Mouse Pancreatic Stem Cells Is Age Dependent. Cell Medicine,5：69-73, 2013
• 60.Nishida N, Kudo M, Nishimura T, Arizumi T, Takita M, Kitai S, Yada N, Hagiwara S, Inoue T, Minami Y, Ueshima K, Sakurai T, Yokomichi N, Nagasaka T, Goel A.：Unique association between global DNA hypomethylation and chromosomal alterations in human hepatocellular carcinoma.PLoS One,8(9)e7231, 2013
• 61.Toiyama Y, Takahashi M, Hur K, Nagasaka T, Tanaka K, Inoue Y, Kusunoki M,Boland CR, Goel A.: Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer. J Natl Cancer Inst, 105(12):849-859, 2013
• 62.Hur K, Toiyama Y, Takahashi M, Balaguer F, Nagasaka T, Koike J, Hemmi H, Koi M, Boland CR, Goel A.: MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis.Gut, 62(9):1315-1326, 2013
  

2012年

• 1. Fujiwara T: In vivo imaging of human cancer with telomerase-specific replication-selective adenovirus. In “In Vivo Vellular Imaging Using Fluorescent Proteins” (Hoffman, R. B., ed.), pp129-139, Humana Press, c/o Springer Science + Business Media, LLC, New York, USA, 2012（著書）
• 2.Umeda Y, Yagi T, Sadamori H, Fujiwara T: Small-for-size syndrome after Living donor Liver transplantation. Liver Transplantation, 2012（著書）
• 3.Utsumi M, Matsuda H, Sadamori H, Shinoura S, Umeda Y, Yoshida R, Satoh D, Hashimoto M, Yagi T, Fujiwara T: Resection of metachronous lymph node metastases from hepatocellular carcinoma after hepatectomy: report of four cases. Acta Med Okayama, 66(2): 177-182, 2012
• 4.Kuroda S, Urata Y, Fujiwara T: Ataxia-telangiectasia mutated and the Mre11-Rad50-NBS1 complex: promising targets for radiosensitization. Acta Med Okayama, 66(2): 83-92, 2012
• 5.Bao XH, Takaoka M, Hao HF, Wang ZG, Fukazawa T, Yamatsuji T, Sakurama K, Sun DS, Nagasaka T, Fujiwara T, Naomoto Y: Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity. Anticancer Res, 32(7): 2827-2834, 2012
• 6.Hao HF, Takaoka M, Bao XH, Wang ZG, Tomono Y, Sakurama K, Ohara T, Fukazawa T, Yamatsuji T, Fujiwara T, Naomoto Y: Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer. Biochem Biophys Res Commun, 423(4): 744-749, 2012
• 7.Hitsuda T, Michiue H, Kitamatsu M, Fujimura A, Wang F, Yamamoto T, Han XJ, Tazawa H, Uneda A, Ohmori I, Nishiki T, Tomizawa K, Matsui H: A protein transduction method using oligo-arginine (3R) for the delivery of transcrition factors into cell nuclei. Biomaterials, 33(18): 4665-4672, 2012
• 8.Yukawa H, Watanabe M, Kaji N, Okamoto Y, Tokeshi M, Miyamoto Y, Noguchi H, Baba Y, Hayashi S: Monitoring transplanted adipose tissue-derived stem cells combined with heparin in the liver by fluorescence imaging using quantum dots. Biomaterials, 33(7): 2177-2186, 2012
• 9.Takakura M, Kyo S, Nakamura M, Maida Y, Mizumoto Y, Bono Y, Zhang X, Hashimoto Y, Urata Y, Fujiwara T, Inoue M: Circulating tumour cells detected by a novel adenovirus-mediated system may be a potent therapeutic marker in gynaecological cancers. Br J Cancer, 107(3):448-454, 2012
• 10.Watanabe Y, Hashimoto Y, Kagawa S, Kawamura H, Nagai K, Tanaka N, Urata Y, Fujiwara T: Enhanced antitumor efficacy of telomerase-specific oncolytic adenovirus with valproic acid against human cancer cells. Cancer Gene Ther, 19(11): 767-772, 2012
• 11.Yoshida R, Tazawa H, Hashimoto Y, Yano S, Onishi T, Sasaki T, Shirakawa Y, Kishimoto H, Uno F, Nishizaki M, Kagawa S, Fujiwara T: Mechanism of resistance to trastuzumab and molecular sensitization via ADCC activation by exogenous expression of HER2-extracellular domain in human cancer cells. Cancer Immunol Immunother, 61(11): 1905-1916, 2012
• 12.Niikura N, Iwamoto T, Masuda S, Kumaki N, Xiaoyan T, Shirane M, Mori K, Tsuda B, Okamura T, Saito Y, Suzuki Y, Tokuda Y: Immunohistochemical Ki67 labeling index has similar proliferation predictive power to various gene signatures in breast cancer. Cancer Sci, 103: 1508-1512, 2012
• 13.Noguchi H, Naziruddin B, Shimoda M, Chujo D, Takita M, Sugimoto K, Itoh T, Onaca N, Levy MF, Matsumoto S: A combined continuous density/osmolality gradient for supplemental purification of human islets. Cell Med, 3(1-3): 33-41, 2012
• 14.Oishi K, Noguchi H, Saito H, Yukawa H, Miyamoto Y, Ono K, Murase K, Sawada M, Hayashi S: Novel positive-charged nanoparticles for efficient magnetic resonance imaging of islet transplantation. Cell Med, 3 (1-3): 43-49, 2012
• 15.Yukawa H, Noguchi H, Oishi K, Miyamoto Y, Inoue M, Hasegawa M, Hayashi S, Baba Y: Differentiation of Mouse Pancreatic Stem Cells Into Insulin-Producing Cells by Recombinant Sendai Virus-Mediated Gene Transfer Technology. Cell Med, 3(1-3): 51-61, 2012
• 16. Miyamoto Y, Noguchi H, Yukawa H, Oishi K, Matsushita K, Iwata H, Hayashi S: Cryopreservation of Induced Pluripotent Stem Cells. Cell Med, 3 (1-3): 89-95, 2012
• 17.Saitoh I, Sato M, Iwase Y, Inada E, Nomura T, Akasaka E, Yamasaki Y, Noguchi H: Generation of mouse STO feeder cell lines that confer resistance to several types of selective drugs. Cell Med, 3(1-3): 97-102, 2012
• 18.Takita M, Matsumoto S, Qin H, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Onaca N, Naziruddin B, Levy MF: Secretory Unit of Islet Transplant Objects (SUITO) Index Can Predict Severity of Hypoglycemic Episodes in Clinical Islet Cell Transplantation. Cell Transplant, 21(1): 91-98, 2012
• 19.Shimoda M, Noguchi H, Fujita Y, Takita M, Ikemoto T, Chujo D, Naziruddin B, Levy MF, Kobayashi N, Grayburn PA, Matsumoto S: Improvement of porcine islet isolation by inhibition of trypsin activity during pancreas preservation and digestion using α1-antitrypsin. Cell Transplant, 21(2-3):465-471, 2012
• 20.Noguchi H, Naziruddin B, Shimoda M, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Onaca N, Levy MF, Matsumoto S: Evaluation of osmolality of density gradient for human islet purification. Cell Transplant, 21(2-3): 493-500, 2012
• 21. Shimoda M, Noguchi H, Fujita Y, Takita M, Ikemoto T, Chujo D, Naziruddin B, Levy MF, Kobayashi N, Grayburn PA, Matsumoto S: Islet purification method using large bottles effectively achieves high islet yield from pig pancreas. Cell Transplant, 21(2-3): 501-508, 2012
• 22.Noguchi H, Naziruddin B, Jackson A, Shimoda M, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Ueda M, Okitsu T, Iwanaga Y, Nagata H, Liu X, Kamiya H, Onaca N, Levy MF, Matsumoto S: Comparison of ulinastatin, gabexate mesilate, and nafamostat mesilate in preservation solution for islet isolation. Cell Transplant, 21(2-3): 509-516, 2012
• 23.Noguchi H, Naziruddin B, Jackson A, Shimoda M, Ikemoto T, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Onaca N, Levy MF, Matsumoto S: Fresh islets are more effective for islet transplantation than cultured islets. Cell Transplant, 21(2-3): 517-523, 2012
• 24.Takita M, Matsumoto S, Noguchi H, Shimoda M, Ikemoto T, Chujo D, Tamura Y, Olsen GS, Naziruddin B, Purcell K, Onaca N, Levy MF: Adverse events in clinical islet transplantation: one institutional experience. Cell Transplant, 21(2-3): 547-551, 2012
• 25. Naziruddin B, Matsumoto S, Noguchi H, Takita M, Shimoda M, Fujita Y, Chujo D, Tate C, Onaca N, Lamont J, Kobayashi N, Levy MF: Improved pancreatic islet isolation outcome in autologous transplantation for chronic pancreatitis. Cell Transplant, 21(2-3): 553-558, 2012
• 26.Hayashi T, Misawa H, Nakahara H, Noguchi H, Yoshida A, Kobayashi N, Tanaka M, Ozaki T: Transplantation of osteogenically differentiated mouse iPS cells for bone repair. Cell Transplant, 21(2-3): 591-600, 2012
• 27.Miyamoto Y, Oishi K, Yukawa H, Noguchi H, Sasaki M, Iwata H, Hayashi S: Cryopreservation of human adipose tissue-derived stem/progenitor cells using the silk protein sericin. Cell Transplant, 21(2-3): 617-622, 2012
• 28.Kanamune J, Iwanaga Y, Kina T, Noguchi H, Matsumura K, Uemoto S, Hyon SH: Attenuation of murine graft-versus-host disease by a tea polyphenol. Cell Transplant, 21(5): 909-918, 2012
• 29. Gonzalez-Angulo AM, Iwamoto T, Liu S, Chen H, Do KA, Hortobagyi GN, Mills GB, Meric-Bernstam F, Symmans WF, Pusztai L: Gene expression, molecular class changes, and pathway analysis after neoadjuvant systemic therapy for breast cancer. Clin Cancer Res, 18: 1109-1119, 2012
• 30.Sawada Y, Yoshikawa T, Nobuoka D, Shirakawa H, Kuronuma T, Motomura Y, Mizuno S, Ishii H, Nakachi K, Konishi M, Nakagohri T, Takahashi S, Gotohda N, Takayama T, Yamao K, Uesaka K, Furuse J, Kinoshita T, Nakatsura T: Phase I trial of glypican-3-derived peptide vaccine for advanced hepatocellular carcinoma showed immunological evidence and potential for improving overall survival. Clin Cancer Res, 18(13): 3686-3696, 2012
• 31.Yagi T, Shinoura S, Umeda Y, Sato D, Yoshida R, Yoshida K, Utsumi M, Nobuoka D, Sadamori H, Fujiwara T: Surgical rationalization of living donor liver transplantation by abolition of hepatic artery reconstruction under a fixed microscope. Clin Transplant, 26(6): 877-883, 2012
• 32.Fujiwara T, Kagawa S，Tazawa H: Synergistic interaction of telomerase-specific oncolytic virotherapy and chemotherapeutic agents for human cancer. Curr Pharm Biotechnol, 13(9): 1809-1816, 2012
• 33.Sadamori H, Yagi T, Matsuda H, Shinoura S, Umeda Y, Fujiwara T: Intractable bile leakage after hepatectomy for hepatocellular carcinoma in 359 recent cases. Dig Surg, 29(2): 149-156, 2012
• 34. Yamasaki Y, Tazawa H, Hashimoto Y, Kojima T, Kuroda S, Yano S, Yoshida R, Uno F, Mizuguchi H, Ohtsuru A, Urata Y, Kagawa S，Fujiwara T: A novel apoptotic mechanism of genetically engineered adenovirus-mediated tumour-specific p53 overexpression through E1A-dependent p21 and MDM2 suppression. Eur J Cancer, 48(14): 2282-2291, 2012
• 35.Obika M, Noguchi H: Diagnosis and evaluation of nonalcoholic Fatty liver disease. Exp Diabetes Res, 145754 (online only journal), 2012
• 36.Matsuda H, Sadamori H, Umeda Y, Shinoura S, Yoshida R, Satoh D, Utsumi M, Yagi T, Fujiwara T: Preventive effect of omental flap in pancreaticoduodenectomy against postoperative pseudoaneurysm formation. Hepatogastroenterology, 59(114): 578-583, 2012
• 37.Toyooka S, Kiura K, Takemoto M, Oto T, Takigawa N, Fujiwara T, Miyoshi S, Date H: Long-term outcome of induction chemoradiotherapy with docetaxel and cisplatin followed by surgery for non-small-cell lung cancer with mediastinal lymph node metastasis. Interact Cardiovasc Thorac Surg, 14(5): 565-569, 2012
• 38.Tazawa H, Yano S, Yoshida R, Yamasaki Y, Sasaki T, Hashimoto Y, Kuroda S, Ouchi M, Onishi T, Uno F, Kagawa S, Urata Y, Fujiwara T: Genetically engineered oncolytic adenovirus induces autophagic cell death through an E2F1-microRNA-7-epidermal growth factor receptor axis. Int J Cancer, 131(12): 2939-2950, 2012
• 39.Tanaka S, Shiraha H, Nakanishi Y, Nishina S, Matsubara M, Horiguchi S, Takaoka N, Iwamuro M, Kataoka J, Kuwaki K, Hagihara H, Toshimori J, Ohnishi H, Takaki A, Nakamura S, Nouso K, Yagi T, Yamamoto K: Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma. Int J Cancer, 131(11): 2537-2546, 2012
• 40.Matsumi J, Morimatsu H, Matsusaki T, Kaku R, Shimizu H, Takahashi T, Yagi T, Matsumi M, Morita K: Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation. Int J Mol Med, 29:135-140, 2012
• 41. Nobuoka D, Motomura Y, Shirakawa H, Yoshikawa T, Kuronuma T, Takahashi M, Nakachi K, Ishii H, Furuse J, Gotohda N, Takahashi S, Nakagohri T, Konishi M, Kinoshita T, Komori H, Baba H, Fujiwara T, Nakatsura T: Radiofrequency ablation for hepatocellular carcinoma induces glypican-3 peptide-specific cytotoxic T lymphocytes. Int J Oncol, 40(1): 63-70, 2012
• 42.Ueki H, Watanabe M, Kaku H, Huang P, Li SA, Ochiai K, Hirata T, Noguchi H, Yamada H, Takei K, Nasu Y, Kashiwakura Y, Kumon H: A novel gene expression system for detecting viable bladder cancer cells. Int J Oncol, 41(1): 135-140, 2012
• 43.Iwamoto T, Booser D, Valero V, Murray JL, Koenig K, Esteva FJ, Ueno NT, Zhang J, Shi W, Qi Y, Matsuoka J, Yang EJ, Hortobagyi GN, Hatzis C, Symmans WF, Pusztai L: Estrogen Receptor (ER) mRNA and ER-Related Gene Expression in Breast Cancers That Are 1% to 10% ER-Positive by Immunohistochemistry. J Clin Oncol, 30: 729-734, 2012
• 44.Sadamori H, Fujiwara H, Tanaka T, Yanai H, Satoh D, Yagi T，Fujiwara T: Carcinosarcoma of the gallbladder manifesting as cholangitis due to hemobilia. J Gastrointest Surg, 16(6): 1278-1281, 2012
• 45.Yoshida R, Yagi T, Sadamori H, Matsuda H, Shinoura S, Umeda Y, Sato D, Utsumi M, Nagasaka T, Okazaki N, Date A, Noguchi A, Tanaka A, Hasegawa Y, Sakamoto Y, Fujiwara T: Branched-chain amino acid-enriched nutrients improve nutritional and metabolic abnormalities in the early post-transplant period after living donor liver transplantation. J Hepatobiliary Pancreat Sci, 19(4): 438-448, 2012
• 46.Yamada E, Shirakawa Y, Yamatsuji T, Sakuma L, Takaoka M, Yamada T, Noma K, Sakurama K, Fujiwara Y, Tanabe S, Nagasaka T, Fujiwara T, Naomoto Y: Jejunal interposition reconstruction with a stomach preserving esophagectomy improves postoperative weight loss and reflux symptoms for esophageal cancer patients. J Surg Res, 178(2):700-707, 2012
• 47.Kelly CM, Bernard PS, Krishnamurthy S, Wang B, Ebbert MT, Bastien RR, Boucher KM, Young E, Iwamoto T, Pusztai L: Agreement in risk prediction between the 21-gene recurrence score assay (Oncotype DX(R)) and the PAM50 breast cancer intrinsic Classifier in early-stage estrogen receptor-positive breast cancer. Oncologist, 17:492-498, 2012
• 48. Yamauchi H, Woodward WA, Valero V, Alvarez RH, Lucci A, Buchholz TA, Iwamoto T, Krishnamurthy S, Yang W, Reuben JM, Hortobagyi GN, Ueno NT : Inflammatory breast cancer: what we know and what we need to learn. Oncologist, 17: 891-899, 2012
• 49. Sugimoto M, Watanabe M, Kaku H, Li SA, Noguchi H, Ueki H, Sakaguchi M, Huh NH, Nasu Y, Kumon H: Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy. Oncol Rep, 28(5):1645-1652, 2012
• 50.Hashimoto Y, Tazawa H, Teraishi F, Kojima T, Watanabe Y, Uno F, Yano S, Urata Y, Kagawa S, Fujiwara T: The hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironment. PLoS One, 7(6)1-10, 2012
• 51.Zhang W, Kai K, Choi DS, Iwamoto T, Nguyen YH, Wong H, Landis MD, Ueno NT, Chang J, Qin L: Microfluidics separation reveals the stem-cell-like deformability of tumor-initiating cells. Proc Natl Acad Sci U S A, 109:18707-18712, 2012
• 52. Takehara K, Aoki H, Takehara Y, Yamasaki R, Tanakaya K, Takeuchi H: Primary hepatic leiomyosarcoma with liver metastasis of rectal cancer. World J Gastroenterol, 18(38): 5479-5484, 2012

2011年

• 1. Kishimoto H, Aki R, Urata Y, Bouvet M, Moriyama M, Tanaka N, Fujiwara T, Hoffman R. M: Tumor-selective adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection． Cell Cycle，210: 2737-2741，2011
• 2.Tazawa H, Kagawa S, Fujiwara T: MicroRNAs as potential target gene in cancer gene therapy of gastrointestinal tumors. Expert Opin Biol Ther，11(2): 145-155，2011
• 3.Shirakawa Y, Tanabe S, Noma K, Sakurama K, Fujiwara T: Surgery for cancers at the esophagogastric junction and Barrett's esophageal cancers．Nihon Rinsho.　(Japanese)，69 (Suppl 6): 322-328，2011
• 4.Fujiwara T: A novel molecular therapy using bioengineered adenovirus for human gastrointestinal cancer. Acta Med Okayama，65(3): 151-162，2011
• 5.Takeda M, Nagasaka T, Dong-Sheng S, Nishie H, Oka T, Yamada E, Mori Y, Shigeyasu K, Morikawa T, Mizobuchi S, Fujiwara T: Expansion of CpG methylation in the SFRP2 promoter region during colorectal tumorigenesis. Acta Med Okayama，65(3): 169-177，2011
• 6.Sasaki T, Tazawa H, Hasei J, Kunisada T, Yoshida A, Hashimoto Y, Yano S,Yoshida R, Uno F, Kagawa S, Morimoto Y, Urata Y, Ozaki T, Fujiwara T: Preclinical evaluation of telomerase-specific oncolytic virotherapy for human bone and soft tissue sarcomas. Clin Cancer Res，17(7): 1828-1838，2011
• 7.Sugio K, Sakurai F, Katayama K, Tashiro K, Matsui H, Kawabata K, Kawase A, Iwaki M, Hayakawa T, Fujiwara T, Mizuguchi H: Enhanced safety profiles of the telomerase-specific replication-competent adenovirus by incorporation of normal cell-specific microRNA-targeted sequences. Clin Cancer Res，17(9): 2807-2818，2011
• 8.Fujiwara T, Shirakawa Y, Kagawa S: Telomerase-specific oncolytic virotherapy for human gastrointestinal cancer．Expert Rev Anticancer Ther，11(4): 525-532，2011
• 9.Motoki T, Naomoto Y, Hoshiba J, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M, Tomono Y, Fujiwara Y, Tsuchita H, Gunduz M, Nagatsuka H, Tanaka N, Fujiwara T: Glutamine depletion induces murine neonatal melena with increased apoptosis of the intestinal epithelium. World J Gastroenterol，17(6): 717-726，2011
• 10.Tanabe S, Naomoto Y, Shirakawa Y, Fujiwara Y, Sakurama K, Noma K, Takaoka M, Yamatsuji T, Hiraki T, Okumura Y, Mitani M, Kaji M, Kanazawa S, Fujiwara T: F-18 FDG PET/CT contributes to more accurate detection of lymph nodal metastasis from actively proliferating esophageal squamous cell carcinoma．Clin Nucl Med，36(10): 854-859，2011
• 11.Ohara T, Takaoka M, Toyooka S, Tomono Y, Nishikawa T, Shirakawa Y, Yamatsuji T, Tanaka N, Fujiwara T, Naomoto Y: Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells．Cancer Sci，102(7): 1344-1349，2011
• 12.Umeda Y, Matsuda H, Sadamori H, Shinoura S, Yoshida R, Sato D, Utsumi M, Yagi T, Fujiwara T: Leukoencephalopathy syndrome after living-donor liver transplantation. Exp Clin Transplant，9(2): 139-144，2011
• 13.Iwamoto T, Bianchini G, Qi Y, Cristofanilli M, Lucci A, Woodward WA, Reuben JM, Matsuoka J, Gong Y, Krishnamurthy S, Valero V, Hortobagyi GN, Robertson F, Symmans WF, Pusztai L, Ueno NT: Different gene expressions are associated with the different molecular subtypes of inflammatory breast cancer. Breast Cancer Res Treat, 125: 785-795，2011
• 14. Iwamoto T, Bianchini G, Booser D, Qi Y, Coutant C, Shiang CY, Santarpia L, Matsuoka J, Hortobagyi GN, Symmans WF, Holmes FA, O'Shaughnessy J, Hellerstedt B, Pippen J, Andre F, Simon R, Pusztai L: Gene Pathways Associated With Prognosis and Chemotherapy Sensitivity in Molecular Subtypes of Breast Cancer．J Natl Cancer Inst，103(3): 264-272，2011
• 15.Coutant C, Rouzier R, Qi YA, Lehmann-Che J, Bianchini G, Iwamoto T, Hortobagyi GN, Symmans WF, Uzan S, Andre F, de The H, Pusztai L: Distinct p53 Gene Signatures Are Needed to Predict Prognosis and Response to Chemotherapy in ER-Positive and ER-Negative Breast Cancers. Clinical Cancer Research, 17: 2591-2601，2011
• 16.Hadad S, Iwamoto T, Jordan L, Purdie C, Bray S, Baker L, Jellema G, Deharo S, Hardie DG, Pusztai L, Moulder-Thompson S, Dewar JA, Thompson AM: Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial．Breast Cancer Res Treat，128: 783-794，2011
• 17. Iwamoto T, Lee JS, Bianchini G, Hubbard RE, Young E, Matsuoka J, Kim SB, Symmans WF, Hortobagyi GN, Pusztai L: First generation prognostic gene signatures for breast cancer predict both survival and chemotherapy sensitivity and identify overlapping patient populations. Breast Cancer Res Treat，130: 155-164，2011
• 18. Hayashi N, Iwamoto T, Gonzalez-Angulo AM, Ferrer-Lozano J, Lluch A, Niikura N, Bartholomeusz C, Nakamura S, Hortobagyi GN, Ueno NT: Prognostic impact of phosphorylated HER-2 in HER-2+ primary breast cancer. Oncologist, 16:956-965，16: 956-965，2011
• 19. Niikura N, Kimura M, Iwamoto T, Hayashi N, Shintoku J, Saito Y, Suzuki Y, Tokuda Y: Women prefer adjuvant endocrine therapy to chemotherapy for breast cancer treatment. Breast Cancer, 2011
• 20.Hess KR, Wei C, Qi Y, Iwamoto T, Symmans WF, Pusztai L: Lack of sufficiently strong informative features limits the potential of gene expression analysis as predictive tool for many clinical classification problems．BMC Bioinformatics，12: 463，2011
• 21.Karn T, Pusztai L, Holtrich U, Iwamoto T, Shiang CY, Schmidt M, Muller V, Solbach C, Gaetje R, Hanker L, Ahr A, Liedtke C, Ruckhaberle E, Kaufmann M, Rody A: Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures．PLoS One, 6: e28403，2011
• 22.Harada S, Sato S, Suzuki E, Okumura Y, Hiraki T, Gobara H, Mimura H, Kanazawa S, Kaji M, Fujiwara T: The usefulness of pre-radiofrequency ablation SUV(max) in 18F-FDG PET/CT to predict the risk of a local recurrence of malignant lung tumors after lung radiofrequency ablation． Acta Med Okayama，65(6): 395-402，2011
• 23. Umeda Y, Matsuda H, Sadamori H, Matsukawa H, Yagi T, Fujiwara T: A Prognostic Model and Treatment Strategy for Intrahepatic Recurrence of Hepatocellular Carcinoma after Curative Resection．World J Surg，35(1): 170-177，2011
• 24.Gonzalez-Angulo AM, Iwamoto T, Liu S, Chen H, Do KA, Hortobagyi GN, Mills GB, Meric-Bernstam F, Symmans WF, Pusztai L: Gene expression, molecular class changes, and pathway analysis after neoadjuvant systemic therapy for breast cancer．Clin Cancer Res,18: 1109-1119，2011
• 25.Hadad S, Iwamoto T, Jordan L, Purdie C, Bray S, Baker L, Jellema G, Deharo S, Hardie DG, Pusztai L. Moulder-Thompson S, Dewar JA, Thompson AM: Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial. Breast Cancer Res Treat，128: 783-794，2011
• 26. Fujita Y, Takita M, Shimoda M, Itoh T, Sugimoto K, Noguchi H, Naziruddin B, Levy MF, Matsumoto S: Large human islets secrete less insulin per islet equivalent than smaller islets in vitro．Islets，3(1): 1-5，2011
• 27.Yukawa H, Noguchi H, Hayashi S: Embryonic body formation using the tapered soft stencil for cluster culture device．Biomaterials, 32(15): 3729-3738，2011
• 28.Takita M, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Sorelle JA, Onaca N, Naziruddin B, Levy MF: Cluster analysis of self-monitoring blood glucose assessments in clinical islet cell transplantation for type 1 diabetes．Diabetes Care，34(8): 1799-1803，2011
• 29.Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H: Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1．Biochem Biophys Res Commun，412(2): 391-395，2011
• 30.Akasaki Y, Watanabe M, Yukawa H, Sabarudin A, Inagaki K, Kaji N, Okamoto Y, Tokeshi M, Miyamoto Y, Noguchi H, Umemura T, Hayashi S, Baba Y, Haraguchi H: Estimation of the distribution of intravenously injected adipose tissue-derived stem cells labeled with quantum dots in mice organs through the determination of their metallic components by ICPMS．Anal Chem，83(21): 8252-8258，2011
• 31.Li G, Kawashima H, Ogose A, Ariizumi T, Xu Y, Hotta T, Urata Y, Fujiwara T, Endo N: Eicient virotherapy for osteosarcoma by telomerase-specific oncolytic adenovirus．J Cancer Res Clin Oncol，137: 1037-1051，2011
• 32.Yasunaka T, Takaki A, Yagi T, Iwasaki Y, Sadamori H, Koike K, Hirohata S, Tatsukawa M, Kawai D, Shiraha H, Miyake Y, Ikeda F, Kobashi H, Matsuda H, Shinoura S, Yoshida R, Satoh D, Utsumi M, Onishi T, Yamamoto K(Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan): Serum hepatitis B virus DNA before liver transplantation correlates with HBV reinfection rate even under successful low-dose hepatitis B immunoglobulin prophylaxis. Hepatol Int. [Epub ahead of print], 2011
• 33.Takita M, Naziruddin B, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Tamura Y, Olsen GS, Onaca N, Lamont J, Lara LF, Levy MF: Body mass index reflects islet isolation outcome in islet autotransplantation for patients with chronic pancreatitis. Cell Transplant，20(2): 313-322，2011
• 34.Fujiwara T, Kagawa S, Tazawa H: Synergistic Interaction of Telomerase-Specific Oncolytic Virotherapy and Chemotherapeutic Agents for Human Cancer. Curr Pharm Biotechnol, 2011
• 35. Takita M, Naziruddin B, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Onaca N, Lamont J, Lara LF, Levy MF: Implication of pancreatic image findings in total pancreatectomy with islet autotransplantation for chronic pancreatitis. Pancreas，40(1): 103-108，2011
• 36.Ikemoto T, Sugimoto K, Takita M, Shimoda M, Noguchi H, Naziruddin B, Levy MF, Shimada M, Matsumoto S: Japanese Herbal Medicine TJ-48 Prevents Autoimmune Diabetes in NOD Mice. Am J Chin Med，39(4): 743-756，2011
• 37.Matsumoto S, Takita M, Chaussabel D, Noguchi H, Shimoda M, Sugimoto K, Itoh T, Chujo D, Sorelle J, Onaca N, Naziruddin B, Levy MF: Improving Efficacy of Clinical Islet Transplantation with Iodixanol Based Islet Purification, Thymoglobulin Induction and Blockage of IL-1-beta and TNF-alpha. Cell Transplant，20(10): 1641-1647，2011
• 38.Minami K. Doi R, Kawaguchi Y, Nukaya D, Hagiwara Y, Noguchi H, Matsumoto S, Seino S: In vitro generation of insulin-secreting cells from human pancreatic exocrine cells. Journal of Diabetes Investigation，2: 271-275，2011
• 39.Kuise T, Noguchi H：Recent progress in pancreatic islet transplantation. World J Transplant，1(1): 13-18，2011
• 40.Noguchi H：Pancreas procurement and preservation for islet transplantation: personal considerations．J Transplant，783168，

2010年

• 1.Nagasaka T, Rhees J, Kloor M, Gebert J, Naomoto Y, Boland CR, Goel A：Somatic hypermethylation of MSH2 is a frequent event in lynch syndrome colorectal cancers．Cancer Res, 70(8): 3098-3108，2010
• 2. Ohashi K, Takahashi HK, Mori S, Liu K, Wake H, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M, Tanaka N：Advanced glycation end products enhance monocyte activation durinç human mixed lymphocyte reaction．Clin Immunol, 134(3): 345-353，2010
• 3.Ohara T, Takaoka M, Sakurama K, Nagaishi K, Takeda H, Shirakawa Y, Yamatsuji T, Nagasaka T, Matsuoka J, Tanaka N, Naomoto Y：The establishment of a new mouse model with orthotopic esophageal cancer showing the esophageal stricture．Cancer Lett, 293(2): 207-212，2010
• 4.Nagasaka T, Goel A, Hamelin R, Boland CR., Division of Gastroenterology, Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas, United States of America：An optimized pentaplex PCR for detecting DNA mismatch repair-deficient colorectal cancers．PLoS One. 5(2): e9393，2010
• 5.Matsuda H, Sadamori H, Shinoura S, Umeda Y, Yoshida R, Satoh D, Utsumi M, Onishi T, Yagi T：Aggressive combined resection of hepatic inferior vena cava, with replacement by a ringed expanded polytetrafluoroethylene graft, in living-donor liver transplantation for hepatocellular carcinoma beyond the Milan criteria．J Hepatobiliary Pancreat Sci. 17(5): 719-724，2010
• 6.Sadamori H, Yagi T, Matsuda H, Shinoura S, Umeda Y, Yoshida R, Satoh D, Utsumi T,Ohnishi T：Risk factors for major morbidity after hepatectomy for hepatocellular carcinoma in 293 recent cases．J Hepatobiliary Pancreat Sci. 17(5):709-718，2010
• 7.Sakai R, Kagawa S, Yamasaki Y, Kojima T, Uno F, Hashimoto Y, Watanabe Y, Urata Y, Tanaka N, Fujiwara T：Preclinical evaluation of differentially targeting dual virotherapy for human solid cancer. Mol Cancer Ther. 9(6):1884-1893，2010
• 8. Kuroda S, Fujiwara T, Shirakawa Y, Yamasaki Y, Yano S, Uno F, Tazawa H, Hashimoto Y, Watanabe Y, Noma K, Urata Y, Kagawa S, Fujiwara T：Telomerase-Dependent Oncolytic Adenovirus Sensitizes Human Cancer Cells to Ionizing Radiation via Inhibition of DNA Repair Machinery．Cancer Res, 70(22): 9339-9348，2010
• 9. Kojima T, Watanabe Y, Hashimoto Y, Kuroda S, Yamasaki Y, Yano S, Ouchi M, Tazawa H, Uno F, Kagawa S, Kyo S, Mizuguchi H, Urata Y, Tanaka N, Fujiwara T： In vivo biological purging for lymph node metastasis of human colorectal cancer by telomerase-specific oncolytic virotherapy. Ann Surg, 251(6): 1079-1086，2010
• 10.Sonoda R, Naomoto Y, Shirakawa Y, Fujiwara Y, Yamatsuji T, Noma K, Tanabe S,Takaoka M, Gunduz M, Tsujigiwa H, Nagatsuka H, Ohara N, Yoshino T, Takubo K,Vieth M, Tanaka N：Preferential up-regulation of heparanase and cyclooxygenase-2 in carcinogenesis of Barrett's oesophagus and intestinal-type gastric carcinoma．Histopathology，57(1): 90-100，2010
• 11. Bao XH, Naomoto Y, Hao HF, Watanabe N, Sakurama K, Noma K, Motoki T, Tomono Y, Fukazawa T, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M.：Autophagy: Can it become a potential therapeutic target? Int J Mol Med. 25(4): 493-503，2010
• 12.Fukazawa T, Matsuoka J, Yamatsuji T, Maeda Y, Durbin ML, Naomoto Y.：Adenovirus-mediated cancer gene therapy and virotherapy (Review). Int J Mol Med，25(1): 3-10，2010Miyamura T, Chayama K, Yoshida R, Yagi T, Matsukawa H, Ishida T, Washio K, Morishita N, Oda M, Morishima T：Successful treatment of unresectable advanced hepatoblastoma: Living liver transplantation after surgical removal of lung metastasis．Pediatr Transplant，2010
• 13.P Huang, H Kaku, J Chen, Y Kashiwakura, T Saika, Y Nasu, Y Urata, T Fujiwara, M Watanabe, H Kumon：Potent antitumor effects of combined therapy with a telomerase-specific, replication-competent adenovirus (OBP-301) and IL-2 in a mouse model of renal cell carcinoma．Cancer Gene Ther，17(7): 484-491，2010
• 14.Watanabe Y, Kojima T, Kagawa S, Uno F, Hashimoto Y, Kyo S, Mizuguchi H, Tanaka N, Kawamura H, Ichimaru D, Urata Y, Fujiwara T.：A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy．Oncogene, 29(8): 1145-1154，2010
• 15.Shahid JM, Iwamuro M, Sasamoto H, Kubota Y, Seita M, Kawamoto H, Nakaji S, Noguchi H, Yamamoto K, Kobayashi N：Establishment of an immortalized porcine liver cell line JSNK-1 with retroviral transduction of SV40T. Cell Transplant，19(6): 849-856，2010Hao H, Naomoto Y, Bao X, Watanabe N, Sakurama K, Noma K, Motoki T, Tomono Y, Fukazawa T, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M：HSP90 and its inhibitors．Oncol Rep, 23(6): 1483-1492，2010
• 16. Goel A, Nagasaka T, Spiegel J, Meyer R, Lichliter WE, Boland CR：Low frequency of Lynch syndrome among young patients with non-familial colorectal cancer．Clin Gastroenterol Hepatol，8(11): 966-971，2010
• 17.Balaguer F, Link A, Lozano JJ, Cuatrecasas M, Nagasaka T, Boland CR, Goel A. (Department of Internal Medicine, Division of Gastroenterology, Charles A Sammons Cancer Center and Baylor Research Institute, Baylor University Medical Center, Dallas, Texas, USA): Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis．Cancer Res. 70(16): 6609-6618，2010
• 18.Kagawa S, Uno F, Gochi A, Naomoto Y, Fujiwara T.：Portal/splenic Vein Thrombosis Following Splenectomy in Gastric Cancer Surgery．Asian Journal of Surgery, 33(4): 208-211，2010
• 19.Takakura M, Nakamura M, Kyo S, Hashimoto M, Mori N, Ikoma T, Mizumoto Y, Fujiwara T, Urata Y, Inoue M: Intraperitoneal administration of telomerase-specific oncolytic adenovirus sensitizes ovarian cancer cells to cisplatin and affects survival in a xenograft model with peritoneal dissemination. Cancer Gene Ther, 17: 11-19，2010
• 20.Nemunaitis J, Tong A. W, Nemunaitis M, Senzer N, Phadke A P, Bedell C, Adams N, Zhang Y A, Maple P B, Chen S, Pappen B, Burke J, Ichimaru D, Urata Y, Fujiwara T: A phase I study of telomerase specific replication competent oncolytic adenovirus (Telomelysin) for various solid tumors. Mol Ther，18: 429-434，2010
• 21.Kawamoto H, Yuasa T, Kubota Y, Seita M, Sasamoto H, Shahid JM, Hayashi T, Nakahara H, Hassan R, Iwamuro M, Kondo E, Nakaji S, Tanaka N, Kobayashi N.：Characteristics of CD133(+) human colon cancer SW620 cells. Cell Transplant, 19(6):857-864，2010
• 22.Navarro-Alvarez N, Kondo E, Kawamoto H, Hassan W, Yuasa T, Kubota Y, Seita M, Nakahara H, Hayashi T, Nishikawa Y, Hassan RA, Javed SM, Noguchi H, Matsumoto S, Nakaji S, Tanaka N, Kobayashi N, Soto-Gutierrez A：Isolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties. Cell Transplant，19(6):865-877，2010
• 23.Navarro-Alvarez N, Soto-Gutierrez A, Kobayashi N：Hepatic stem cells and liver development．Methods Mol Biol, 640: 181-236，2010
• 24.Fujita H, Kurokawa K, Ogino T, Ono M, Yamamoto M, Oka T, Nakanishi T,　Kobayashi N, Tanaka N, Ogawa T, Suzaki E, Utsumi K, Sasaki J：Effect of Risedronate on Osteoblast Differentiation, Expression of Receptor Activator of NF-κB Ligand and Apoptosis in Mesenchymal Stem Cells. Basic Clin Pharmacol Toxicol. 2010
• 25.Yamamoto T, Navarro-Alvarez N, Soto-Gutierrez A, Yuasa T, Iwamuro M, Kubota Y, Seita M, Kawamoto H, Javed SM, Kondo E, Noguchi H, Kobayashi S, Nakaji S, Kobayashi N：Treatment of acute liver failure in mice by hepatocyte xenotransplantation．Cell Transplant，19(6): 799-806，2010
• 26.Soto-Gutierrez A, Navarro-Alvarez N, Yagi H, Nahmias Y, Yarmush ML, Kobayashi N：Engineering of an hepatic organoid to develop liver assist devices．Cell Transplant，19(6): 815-822，2010
• 27.Nakahara H, Misawa H, Yoshida A, Hayashi T, Tanaka M, Furumatsu T, Tanaka N, Kobayashi N, Ozaki T：Bone repair using a hybrid scaffold of self-assembling peptide PuraMatrix and polyetheretherketone cage in rats．Cell Transplant，19(6):791-797，2010
• 28.Kobayashi N, Amemiya H, Nagao T, Takahara S：Taking a lesson from the past in organ biology．Cell Transplant，19(6): 645-647，2010
• 29.Navarro-Alvarez N, Soto-Gutierrez A, Chen Y, Caballero-Corbalan J, Hassan W, Kobayashi S, Kondo Y, Iwamuro M, Yamamoto K, Kondo E, Tanaka N, Fox IJ, Kobayashi N: Intramuscular transplantation of engineered hepatic tissue constructs corrects acute and chronic liver failure in mice．J Hepatol，52(2): 211-219，2010
• 30.Zhang J, Takahashi HK, Liu K, Wake H, Liu R, Sadamori H, Matsuda H, Yagi T, Yoshino T, Mori S, Nishibori M: Histamine inhibits adhesion molecule expression in human monocytes, induced by advanced glycation end products, during the mixed lymphocyte reaction．Br J Pharmacol, 160(6): 1378-1386，2010
• 31.Takahashi HK, Zhang J, Mori S, Liu K, Wake H, Liu R, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M：Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression on monocytes, cytokine production, and lymphocyte proliferation during human mixed lymphocyte reaction．J Pharmacol Exp Ther，334(3): 964-972，2010
• 32.Kitamura Y, Yagi T, Kitagawa K, Shinomiya K, Kawasaki H, Asanuma M, Gomita Y：Effects of bupropion on the forced swim test and release of dopamine in the nucleus accumbens in ACTH-treated rats．Naunyn Schmiedebergs Arch Pharmacol，382(2): 151-158，2010
• 33.Yumoto Y, Yagi T, Sato S, Nouso K, Kobayashi Y, Ohmoto M, Yumoto E, Nagaya I, Nakatsukasa H：Preoperative estimation of remnant hepatic function using fusion images obtained by (99m)Tc-labelled galactosyl-human serum albumin liver scintigraphy and computed tomography．Br J Surg，97(6): 934-944，2010

2009年

• 1.Ouchi M, Kawamura H, Urata Y, Fujiwara T：Antiviral activity of cidofovir against telomerase-specific replication-selective oncolytic adenovirus, OBP-301 (Telomelysin). Invest New Drugs，27: 241-245，2009
• 2.Watanabe N, Ootawa Y, Kodama K, Kaide A, Ootsuka N, Matsuoka J：Concurrent administration of chemo-endocrine therapy for postmenopausal breast cancer patients．Breast Cancer, 2009
• 3.Sakurama K, Noma K, Takaoka M, Tomono Y, Watanabe N, Hatakeyama S, Ohmori O, Hirota S, Motoki T, Shirakawa Y, Yamatsuji T, Haisa M, Matsuoka J, Tanaka N, Naomoto Y：Inhibition of focal adhesion kinase as a potential therapeutic strategy for imatinib-resistant gastrointestinal stromal tumor. Mol Cancer Ther，8(1): 127-134，2009
• 4.Tabuchi Y, Matsuoka J, Gunduz M, Imada T, Ono R, Ito M, Motoki T, Yamatsuji T, Shirakawa Y, Takaoka M, Haisa M, Tanaka N, Kurebayashi J, Jordan VC, Naomoto Y：Resistance to paclitaxel therapy is related with Bcl-2 expression through an estrogen receptor mediated pathway in breast cancer. Int J Oncol，34(2): 313-319，2009
• 5.Sadamori H, Yagi T, Iwagaki H, Matsuda H, Shinoura S, Umeda Y, Ohara N, Yanai H, Ogino T, Tanaka N：Immunohistochemical staining of liver grafts with a monoclonal antibody against HCV-Envelope 2 for recurrent hepatitis C after living donor liver transplantation．J Gastroenterol Hepatol，24(4): 574-580，2009
• 6.Ikeda Y, Kojima T, Kuroda S, Endo Y, Sakai R, Hioki M, Kishimoto H, Uno F, Kagawa S, Watanabe Y, Hashimoto Y, Urata Y, Tanaka N, Fujiwara T：A novel antiangiogenic effect for telomerase-specific virotherapy through host immune system. J Immunol，182: 1763-1769，2009
• 7.Umeda Y, Iwagaki H, Ozaki M, Ogino T, Iwamoto T, Yoshida R, Shinoura S, Matsuda H, Sadamori H, Tanaka N, Yagi T：Refractory response to growth factors impairs liver regeneration after hepatectomy in patients with viral hepatitis．Hepatogastroenterology，56(93): 971-977，2009
• 8.Kojima T, Hashimoto Y, Watanabe Y, Kagawa S, Uno F, Kuroda S, Tazawa H, Kyo S, Mizuguchi H, Urata Y, Tanaka N, Fujiwara T：A simple biological imaging system for detecting viable human circulating tumor cells. J Clin Invest，119: 3172-3181，2009
• 9.Kamo N, Naomoto Y, Shirakawa Y, Yamatsuji T, Hirota S, Fujiwara Y, Noma K, Sakurama K, Takaoka M, Nagatsuka H, Gunduz M, Matsuoka J, Tanaka N：Involvement of focal adhesion kinase in the progression and prognosis of gastrointestinal stromal tumors．Hum Pathol，40(11): 1643-1649，2009
• 10.Hanazaki M, Takata K, Goto K, Katayama H, Yokoyama M, Morita K, Shirakawa Y, Yamatsuji T, Naomoto Y：Anesthetic management of a patient with Alport-leiomyomatosis syndrome．J Anesth，23(3):453-455，2009
• 11.Mita Y, Yasuda Y, Sakai A, Yamamoto H, Toyooka S, Gunduz M, Tanabe S, Naomoto Y, Ouchida M, Shimizu K：Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers．J Cancer Res Clin Oncol，136(2): 249-259, 2009
• 12.Matsuo N, Shiraha H, Fujikawa T, Takaoka N, Ueda N, Tanaka S, Nishina S, Nakanishi Y, Uemura M, Takaki A, Nakamura S, Kobayashi Y, Nouso K, Yagi T, Yamamoto K：Twist expression promotes migration and invasion in hepatocellular carcinoma．BMC Cancer，9: 240, 2009
• 13.Kato H, Kawamoto H, Tsutsumi K, Harada R, Fujii M, Hirao K, Kurihara N, Mizuno O, Ishida E, Ogawa T, Fukatsu H, Yamamoto K, Yagi T：Long-term outcomes of endoscopic management for biliary strictures after living donor liver transplantation with duct-to-duct reconstruction．Transpl Int，22(9): 914-921，2009
• 14.Ohashi K, Takahashi HK, Mori S, Liu K, Wake H, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M, Tanaka N：Advanced glycation end products enhance monocyte activation during human mixed lymphocyte reaction．Clin Immunol，134(3): 345-353, 2009
• 15.Kishimoto H, Zhao M, Hayashi K, Urata Y, Tanaka N, Fujiwara T, Penman S, Hoffman RM：In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation．Proc Natl Acad Sci USA，106: 14514-14517，2009
• 16.Kishimoto H, Urata Y, Tanaka N, Fujiwara T, Hoffman RM：Selective metastatic tumor labeling with green fluorescent protein and killing by systemic administration of telomerase-dependent adenoviruses．Mol Cancer Ther，8: 3001-3008，2009
• 17.Kominami K, Nagasaka T, Cullings HM, Hoshizima N, Sasamoto H, Young J, Leggett BA, Tanaka N, Matsubara N：Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability．J Int Med Res，37(4): 1038-1045，2009
• 18.Sakurama K, Naomoto Y, Ohara T, Watanabe N, Takaoka M, Nagatsuka H, Tomono Y, Tanida T, Noma K, Tanabe S, Fujiwara Y, Motoki T, Shirakawa Y, Yamatsuji T, Hirota S, Taguchi T, Tanaka N：Establishment of a lymph node metastasis model from subcutaneous tumors of gastrointestinal stromal tumor model cells．Oncol Rep，21(2): 407-411，2009
• 19.Basma Hesham, Soto-Gutierrez Alejandro, Yannam Govardhana Rao, Liu Liping, Ito R, Yamamoto T, Ellis Ewa, Carson Steven D, Sato S, Chen Yong, Muirhead David, Navarro-Alvarez Nalu, Wong Ronald J, Roy-Chowdhury Jayanta, Platt Jeffrey L，Mercer David F，Miller John D, Strom Stephen C，Kobayashi N，Fox Ira J：Differentiation and transplantation of human embryonic stem cell-derived hepatocytes．Gastroenterology, 136(3): 990-999，2009
• 20.Matsumoto S, Noguchi H，Hatanaka N, Shimoda M，Kobayashi N，Jackson Andrew, Onaca Nicholas，Naziruddin, Bashoo, Levy Marlon F：SUITO index for evalutation of efficacy of single donor islet transplantation．Cell Transplantation，18(5-6): 557-562，2009
• 21.Matsumoto S, Noguchi H, Hatanaka N, Shimoda M, Kobayashi N, Jackson A, Onaca N, Naziruddin B, Levy MF：Estimation of donor usability for islet transplantation in the United States with the Kyoto islet isolation method．Cell Transplantation，18(5-6): 549-556, 2009
• 22.Nakahara H, Misawa H，Hayashi T，Kondo E，Yuasa T，Kubota Y，Seita M，Kawamoto H，Hassan Wael Amgad Refaat Ahmed，Hassan Reham Amgad Refaat Ahmed，Javed Shahid Muhammad，Tanaka M，Endo H，Noguchi H，Matsumoto S，Takata K，Tashiro Y，Nakaji S，Ozaki T，Kobayashi N：Bone repair by transplantation of hTERT-immortalized human mesenchymal stem cells in mice．Transplantation，88(3): 346-353，2009
• 23.Nishie M, Tateno C, Utoh R, Kohashi T, Masumoto N, Kobayashi N, Itamoto T, Tanaka N, Asahara T, Yoshizato K：Hepatocytes from fibrotic liver possess high growth potential in vivo．Cell Transplantation, 18(5-6): 665-675，2009
• 24.Noguchi H, Matsumoto S, Onaca N, Naziruddin B, Jackson A, Ikemoto T, Shimoda M, Fujita Y, Chujo D, Iwanaga Y, Nagata H, Okitsu T, Kobayashi N, Ueno H, Chaussabel D, Grayburn P, Banchereau J, Levy MF：Ductal injection of JNK inhibitors before pancreas preservation prevents islet apoptosis and improves islet graft function．Human Gene Therapy，20(1): 73-85，2009
• 25.Noguchi H, Ikemoto T, Naziruddin B, Jackson A, Shimoda M, Fujita Y, Chujo D, Takita M, Kobayashi N, Onaca N, Levy MF, Matsumoto S：Iodixanol-controlled density gradient during islet purification improves recovery rate in human islet isolation．Transplantation，87(11): 1629-1635，2009
• 26.Noguchi H, Oishi K, Ueda M, Yukawa H, Hayashi S, Kobayashi N, Levy MF, Matsumoto S：Establishment of mouse pancreatic stem cell line．Cell Transplantation, 18(5-6): 563-571，2009
• 27.Noguchi H, Ueda M, Hayashi S, Kobayashi N, Okitsu T, Iwanaga Y, Nagata H, Liu X, Kamiya H, Levy MF, Matsumoto S：Comparison of trypsin inhibitors in preservation solution for islet isolation．Cell Transplantation，18(5-6): 541-547，2009
• 28.Yuasa T, Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Kubota Y, Tabata Y, Okitsu T, Noguchi H, Matsumoto S, Nakaji S, Tanaka N, Kobayashi N：Neovascularization induced around an artificial device implanted in the abdomen by the use of gelatinized fibroblast growth factor 2．Cell Transplantation，18(5-6): 683-688，2009
• 29.Kobayashi N：Life support of artificial liver：development of a bioartificial liver to treat liver failure．Journal of Hepato-biliary-pancreatic Surgery，16(2): 113-117，2009
• 30.Kobayashi N, Yuasa T, Okitsu T：Regenerative medicine for diabetes mellitus．Cell Transplantation，18(5-6): 491-496，2009
• 31.Noguchi H, Levy Marlon F，Kobayashi N, Matsumoto S：Pancreas preservation by the Two-Layer Method: Does it have a beneficial effect compared with simple preservation in University of Wisconsin solution? Cell Transplantation，18(5-6): 497-503，2009
• 32.Navarro-Alvarez Nalu, Soto-Gutierrez Alejandro，Kobayashi N：Stem cell research and therapy for liver disease．Current Stem Cell Research & Therapy，4(2): 141-146，2009
• 33.Chan-On Waraporn, Kuwahara K, Kobayashi N, Ohta K, Shimasaki T, Sripa B, Leelayuwat C, Sakaguchi N：Cholangiocarcinomas associated with long-term inflammation express the activation-induced cytidine deaminase and germinal center-associated nuclear protein involved in immunoglobulin V-region diversification．International Journal of Oncology，35(2): 287-295，2009
• 34.Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M：Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells．J Pharmacol Exp Ther，330(1): 89-98，2009
• 35.Nagasaka T, Tanaka N, Cullings HM, Sun DS, Sasamoto H, Uchida T, Koi M, Nishida N, Naomoto Y, Boland CR, Matsubara N, Goel A：Analysis of fecal DNA methylation to detect gastrointestinal neoplasia．J Natl Cancer Inst，101(18): 1244-1258，2009
• 36.Nishibori M, Takahashi HK, Katayama H, Mori S, Saito S, Iwagaki H, Tanaka N, Morita K, Ohtsuka A：Specific Removal of Monocytes from Peripheral Blood of Septic Patients by Polymyxin B-immobilized Filter Column. Acta Med Okayama，63(1): 65-69，2009
• 37.Hao HF, Naomoto Y, Bao XH, Watanabe N, Sakurama K, Noma K, Tomono Y, Fukazawa T, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M：Progress in researches about focal adhesion kinase in gastrointestinal tract．World J Gastroenterol，15(47): 5916-5923，2009
• 38.Fukazawa T, Fukazawa T, Maeda Y, Matsuoka J, Tanaka N, Tanaka H, Durbin ML, Naomoto Y：Drug-regulatable cancer cell death induced by BID under control of the tissue-specific, lung cancer-targeted TTS promoter system．Int J Cancer，125(8): 1975-1984，2009
• 39.Domae S, Nakamura Y, Nakamura Y, Uenaka A, Wada H, Nakata M, Oka M, Kishimoto K, Tsukamoto G, Yoshihama Y, Matsuoka J, Gochi A, Kohno S, Saika T, Sasaki A, Nakayama E, Ono T：Identification of CCDC62-2 as a novel cancer/testis antigen and its immunogenicity．Int J Cancer，124(10): 2347-2352，2009
• 40.Sadamori H, Matsuda H, Shinoura S, Umeda Y, Yoshida R, Sato D, Utsumi H, Ohnishi T, Yagi T：Anatomical subsegmentectomy in the lateral segment for hepatocellular carcinoma．Hepatogastroenterology，56(94-95): 1511-1515，2009
• 41.Nakajima O, Matsunaga A, Ichimaru D, Urata Y, Fujiwara T, Kawakami K：Telomerase-specific virotherapy in an animal model of human head and neck cancer. Mol Cancer Ther，8: 171-177，2009
• 42.Kurihara Y, Watanabe Y, Onimatsu H, Kojima T, Shirota T, Hatori M, Liu D, Kyo S, Mizuguchi H, Urata Y, Shintani S, Fujiwara T：Telomerase-specific virotheranostics for human head and neck cancer．Clin Cancer Res，15: 2335-2343，2009
• 43.Liu D , Kojima, T, Ouchi, M, Kuroda, S, Watanabe, Y, Hashimoto, Y, Onimatsu, H, Urata, Y, Fujiwara, T：Preclinical evaluation of synergistic effect of telomerase-specific oncolytic virotherapy and gemcitabine for human lung cancer．Mol Cancer Ther，8: 980-987，2009
• 44.Takakura M , Nakamura M, Kyo S, Hashimoto M, Mori N, Ikoma T, Mizumoto Y, Fujiwara T, Urata Y, Inoue M: Intraperitoneal administration of telomerase-specific oncolytic adenovirus sensitizes ovarian cancer cells to cisplatin and affects survival in a xenograft model with peritoneal dissemination．Cancer Gene Ther，2009
• 45.Nemunaitis J, Tong AW, Nemunaitis M, Senzer N, Phadke A P, Bedell C, Adams N, Zhang Y A, Maple PB, Chen S, Pappen B, Burke J, Ichimaru D, Urata Y, Fujiwara T: A phase I study of telomerase-specific replication competent oncolytic adenovirus (Telomelysin) for various solid tumors. Mol Ther, 18(2): 429-34，2009
• 46.Matsumoto S, Noguchi H，Shimoda M，Ikemoto T，Naziruddin, Bashoo, Jackson Andrew，Tamura Y, Olson G, Fujita Y, Chujo D, Takita M, Kobayashi N，Onaca N, Levy M：Seven consecutive successful clinical islet isolations with pancreatic ductal injection．Cell Transplantation，2009
• 47.Hao H, Naomoto Y, Bao X, Watanabe N, Sakurama K, Noma K, Motoki T, Tomono Y, Fukazawa T, Shirakawa Y, Yamatsuji T, Matsuoka J, Wang ZG, Takaoka M：Focal adhesion kinase as potential target for cancer therapy (Review)．Oncol Rep，22(5): 973-979，2009
• 48.Fujiwara Y, Naomoto Y, Tanabe S, Sakurama K, Noma K, Nishikawa T, Motoki T, Takaoka M, Shirakawa Y, Yamatsuji T, Matsuoka J: A case report of FOLFOX treatment for primary duodenal carcinoma with multiple liver metastases. Gan To Kagaku Ryoho, 36(4): 655-657，2009
• 49.Nakagawa H, Nagasaka T, Cullings HM, Notohara K, Hoshijima N, Young J, Lynch HT, Tanaka N, Matsubara N：Efficient molecular screening of Lynch syndrome by specific 3' promoter methylation of the MLH1 or BRAF mutation in colorectal cancer with high-frequency microsatellite instability. Oncol Rep，21(6): 1577-1583，2009
• 50.Fujiwara T: Telomerase-specific virotherapy for human squamous cell carcinoma．Expert Opin Biol Ther，9: 321-329，2009
• 51.Watanabe Y, Kojima T, Kagawa S, Uno F, Hashimoto Y, Kyo S, Mizuguchi H, Tanaka N, Kawamura H, Ichimaru D, Urata Y, Fujiwara T：A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy．Oncogene, 29(8): 1145-1154，2009
• 52.Maida Y, Kyo S, Sakaguchi J, Mizumoto Y, Hashimoto M, Mori N, Ikoma T, Nakamura M, Takakura M, Urata Y, Fujiwara T, Inoue M：Diagnostic potential and limitation of imaging cancer cells in cytological samples using telomerase-specific replicative adenovirus．Int J Oncol，34: 1549-1556，2009
• 53.Nakajima O, Ichimaru D, Urata Y, Fujiwara T, Horibe T, Kohno M, Kawakami K: Use of telomelysin (OBP-301) in mouse xenografts of human head and neck cancer. Oncol Rep，22: 1039-1043，2009
• 54.Vilkin A, Niv Y, Nagasaka T, Morgenstern S, Levi Z, Fireman Z, Fuerst F, Goel A, Boland CR：Microsatellite instability, MLH1 promoter methylation, and BRAF mutation analysis in sporadic colorectal cancers of different ethnic groups in Israel．Cancer, 115(4): 760-769，2009
• 55.Egi M, Toda Y, Katayama H, Yokoyama M, Morita K, Arai H, Yamatsuji T, Bailey M, Naomoto Y：Safer glycemic control using isomaltulose-based enteral formula: A pilot randomized crossover trial. J Crit Care，25(1): 90-96，2009
• 56.Link A, Shin SK, Nagasaka T, Balaguer F, Koi M, Jung B, Boland CR, Goel A JC: virus mediates invasion and migration in colorectal metastasis．PLoS One, 4(12): e8146，2009

2008年

• 1.Iwamoto T, Yagi T, Umeda Y, Sato D, Matsukawa H, Matsuda H, Shinoura S, Sadamori H, Mizuno K, Yoshida R, Tanaka N：The impact of donor age on the outcome of adult living donor liver transplantation．Transplantation, 85(9): 1240-1245, 2008
• 2.Yuasa T, Yamamoto T, Rivas-Carrillo JD, Chen Y, Navarro-Alvarez N, Soto-Guiterrez A, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N：Laparoscopy-assisted creation of a liver failure model in pigs．Cell Transplant, 17(1-2): 187-193, 2008
• 3.Navarro-Alvarez N, Rivas-Carrillo JD, Soto-Gutierrez A, Yuasa T, Okitsu T, Noguchi H, Matsumoto S, Takei J, Tanaka N, Kobayashi N：Reestablishment of microenvironment is necessary to maintain in vitro and in vivo human islet function．Cell Transplant, 17(1-2): 111-119, 2008
• 4.Navarro-Alvarez N, Soto-Gutierrez A, Yuasa T, Yamatsuji T, Shirakawa Y, Nagasaka T, Sun SD, Javed MS, Tanaka N, Kobayashi N：Long-term culture of Japanese human embryonic stem cells in feeder-free conditions．Cell Transplant, 17(1-2): 27-33, 2008
• 5.Kobayashi N, Navarro-Alvarez N, Soto-Gutierrez A, Kawamoto H, Kondo Y, Yamatsuji T, Shirakawa Y, Naomoto Y, Tanaka N：Cancer stem cell research: current situation and problems．Cell Transplant, 17(1-2): 19-25, 2008
• 6.Soto-Gutierrez A, Navarro-Alvarez N, Caballero-Corbalan J, Tanaka N, Kobayashi N: Endoterm induction for hepatic and pancreatic differentiation of ES cells．Acta Med Okayama, 62(2): 63-68, 2008
• 7.Murata T, Naomoto Y, Yamatsuji T, Okawa T, Shirakawa Y, Gunduz M, Nobuhisa T, Takaoka M, Sirmali M, Nakajima M, Ohno Y, Tanaka N：Localization of FAK is related with colorectal carcinogenesis．Int J Oncol, 32(4): 791-796, 2008
• 8.Nakagawa Y, Uemura S, Nakaoka T, Yano T, Tanaka N：Evaluation of the Nuss procedure using pre- and postoperative computed tomographic index．J Pediatr Surg, 43(3): 518-521, 2008
• 9.Hioki M, Kagawa S, Fujiwara T, Sakai R, Kojima T, Watanabe Y, Hashimoto Y, Uno F, Tanaka N, Fujiwara T：Combination of oncolytic adenovirotherapy and Bax gene therapy in human cancer xenografted models. Potential merits and hurdles for combination therapy．Int J Cancer, 122(11): 2628-2633, 2008
• 10.Nagasaka T, Goel A, Notohara K, Takahata T, Sasamoto H, Uchida T, Nishida N, Tanaka N, Boland CR, Matsubara N：Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis．Int J Cancer, 122(11): 2429-2436, 2008
• 11.Sadamori H, Yagi T, Matsukawa H, Matsuda H, Shinoura S, Umeda Y, Iwamoto T, Satoh D, Tanaka N：The outcome of living donor liver transplantation with prior spontaneous large portasystemic shunts．Transpl Int, 21(2): 156-162, 2008
• 12.Endo Y, Sakai R, Ouchi M, Onimatsu H, Hioki M, Kagawa S, Uno F, Watanabe Y, Urata Y, Tanaka N, Fujiwara T：Virus-mediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation．Oncogene, 27(17): 2375-2381, 2008
• 13.Fujiwara T, Urata Y, Tanaka N：Diagnostic and therapeutic application of telomerase-specific oncolytic adenoviral agents．Front Biosci, 13: 1881-1886, 2008
• 14.Hamano R, Takahashi HK, Iwagaki H, Kanke T, Liu K, Yoshino T, Sendo T, Nishibori M, Tanaka N：Stimulation of adenosine A2A receptor inhibits LPS-induced expression of intercellular adhesion molecule 1 and production of TNF-alpha in human peripheral blood mononuclear cells．Shock, 29(2): 154-159, 2008
• 15.Matsusaki T, Morimatsu H, Takahashi T, Matsumi M, Sato K, Kaku R, Sato T, Yagi T, Tanaka N, Morita K：Increased exhaled carbon monoxide concentration during living donor liver transplantation．Int J Mol Med, 21(1): 75-81, 2008
• 16.Sadamori H, Yagi T, Matsukawa H, Matsuda H, Shinoura S, Umeda Y, Narushima M, Tanaka N：Successful re-transection of conglutinated hepatic resection plane for repeated systematized hepatectomy. Hepatogastroenterology, 55(82-83): 363-366, 2008
• 17.Watanabe N, Takaoka M, Sakurama K, Tomono Y, Hatakeyama S, Ohmori O, Motoki T, Shirakawa Y, Yamatsuji T, Haisa M, Matsuoka J, Beer DG, Nagatsuka H, Tanaka N, Naomoto Y: Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-I receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo．Clin Cancer Res, 14(14): 4631-4639, 2008
• 18.Ono R, Matsuoka J, Yamatsuji T, Naomoto Y, Tanaka N, Matsui H, Matsushita M：M-RIP, a novel target of JNK signaling and a requirement for human cancer cell invasion．Int J Mol Med, 22(2):199-203, 2008
• 19.Fukazawa T, Matsuoka J, Naomoto Y, Maeda Y, Durbin ML, Tanaka N：Malignant pleural mesothelioma-targeted CREBBP/EP300 inhibitory protein 1 promoter system for gene therapy and virotherapy. Cancer Res, 68(17): 7120-7129, 2008
• 20.Yoshida R, Iwamoto T, Yagi T, Sato D, Umeda Y, Mizuno K, Shinoura S, Matsukawa H, Matsuda H, Sadamori H, Tanaka N：Preoperative Assessment of the Risk Factors that Help to Predict the Prognosis After Living Donor Liver Transplantation．World J Surg, 32(11): 2419-2424, 2008
• 21.Umeda Y, Yagi T, Sadamori H, Matsukawa H, Matsuda H, Shinoura S, Mizuno K, Yoshida R, Iwamoto T, Satoh D, Tanaka N：Effects of prophylactic splenic artery modulation on portal overperfusion and liver regeneration in small-for-size graft．Transplantation, 86(5): 673-680, 2008
• 22.Hashimoto Y, Watanabe Y, Shirakiya Y, Uno F, Kagawa S, Kawamura H, Nagai K, Tanaka N, Kumon H, Urata Y, Fujiwara T：Establishment of biological and pharmacokinetic assays of telomerase-specific replication-selective adenovirus．Cancer Sci, 99(2): 385-390, 2008
• 23.Otani S, Kuinose M, Murakami T, Saito S, Iwagaki H, Tanaka N, Tanemoto K：Preoperative oral administration of pentoxifylline ameliorates respiratory index after cardiopulmonary bypass through decreased production of IL-6．Acta Med Okayama, 62(2): 69-74, 2008
• 24.Noma K, Smalley KS, Lioni M, Naomoto Y, Tanaka N, El-Deiry W, King AJ, Nakagawa H, Herlyn M：The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis. Gastroenterology, 134(7): 1981-1993, 2008
• 25.Rivera RS, Nagatsuka H, Siar CH, Gunduz M, Tsujigiwa H, Han PP, Katase N, Tamamura R, Ng KH, Naomoto Y, Nakajima M, Nagai N：Heparanase and vascular endothelial growth factor expression in the progression of oral mucosal melanoma．Oncol Rep , 9(3): 657-661, 2008
• 26.Fukatsu H, Kawamoto H, Harada R, Fujii M, Tsutsumi K, Ogawa T, Ishida E, Okada H, Sakaguchi K, Yagi T, Matsukawa H, Sadamori H, Ohmori M：Cholesterolosis of the common bile duct with anomalous arrangement of the pancreaticobiliary ductal system．Gastrointest Endosc, 67(7): 1172-1173, 2008
• 27.Matsusaki T, Morimatsu H, Takahashi T, Matsumi M, Sato K, Kaku R, Sato T, Yagi T, Tanaka N, Morita K：Increased exhaled carbon monoxide concentration during living donor liver transplantation．Int J Mol Med, 21(1): 75-81, 2008
• 28.Takaki A, Suzuki H, Iwasaki Y, Takigawa T, Ogino K, Matsuda H, Yagi T, Hanazaki M, Nakatsuka H, Katayama H, Matsumi M, Shoji B, Terada R, Kobashi H, Sakaguchi K: A 27-year-old man who died of acute liver failure probably due to trichloroethylene abuse．J Gastroenterol, 43(3): 239-242, 2008
• 29.Ohara T, Oto T, Miyoshi K, Tao H, Yamane M, Toyooka S, Okazaki M, Date H, Sano Y：Sirolimus ameliorated post lung transplant chylothorax in lymphangioleiomyomatosis．Ann Thorac Surg, 86(6): e7-8, 2008
• 30.Yoshida R, Iwamoto T, Yagi T, Sato D, Umeda Y, Mizuno K, Shinoura S, Matsukawa H, Matsuda H, Sadamori H, Tanaka N.：Preoperative assessment of the risk factors that help to predict the prognosis after living donor liver transplantation．World J Surg, 32(11): 2419-2424, 2008
• 31.Naoya Kobayashi：Artificial cells for the development of cell therapy. Cell Transplantation, 17(1-2): 3-9, 2008
• 32.Naoya Kobayashi：Bioartificial pancreas for the treatment of diabetes．Cell Transplantation, 17(1-2): 11-17, 2008
• 33.Hirofumi Noguchi, Michiko Ueda, Shuji Hayashi, Naoya Kobayashi, Teru Okitsu, Yasuhiro Iwanaga, Hideo Nagata, Yusuke Nakai, Shinichi Matsumoto：Ductal injection of preservation solution increases islet yields in islet isolation and improves islet graft function．Cell Transplantation, 17(1-2): 69-81, 2008
• 34.Michiko Ueda, Shinichi Matsumoto, Shuji Hayashi, Naoya Kobayashi, Hirofumi Noguchi：Cell surface heparan sulfate proteoglycans mediate the internalization of PDX-1 protein．Cell Transplantation, 17(1-2): 91-97, 2008
• 35.Hirofumi Noguchi, Yuichiro Yamada, Teru Okitsu, Yasuhiro Iwanaga, Hideo Nagata, Naoya Kobayashi, Shuji Hayashi, Shinichi Matsumoto：Secretory unit of islet in transplantation (SUIT) and engrafted islet rate (EIR) indexes are useful for evaluating single islet transplantation. Cell Transplantation, 17(1-2): 121-128, 2008
• 36.Masahiro Ito, Ryoutaro Ito, Daisuke Yoshihara, Masashi Ikeno, Megumi Kamiya, Nobutaka Suzuki, Akihiko Horiguchi, Hideo Nagata, Toshiyuki Yamamoto, Naoya Kobayashi, Ira J. Fox, Tsuneko Okazaki, Syuichi Miyakama: Immortalized hepatocytes using human artificial chromosome．Cell Transplantation, 17(1-2): 165-171, 2008
• 37.Naoya Kobayashi：The current status of islet transplantation and its perspectives. Review of diabetic studies, 5(3): 136-143, 2008
• 38.Naoya Kobayashi：Life support of artificial liver: development of a bioartificial liver to treat liver failure．Journal of hepato-biliary-pancreatic surgery, 2008
• 39.Naoya Kobayashi, Nalu Navarro-Alvarez, Alejandro Soto-Gutierrez, Hironobu Kawamoto, Yoshitaka Kondo, Tomoki Yamatsuji, Yasuhiro Shirakawa, Yoshio Naomoto, Noriaki Tanaka: Cancer stem cell research: current situation and problems．Cell Transplantation, 17(1-2): 19-25, 2008
• 40.Nalu Navarro-Alvarez, Alejandro Soto-Gutierrez, Takeshi Yuasa, Tomoki Yamatsuji, Yasuhiro Shirakawa, Takeshi Nagasaka, Sheng Sun D., Muhammad Shahid Javed, Noriaki Tanaka, Naoya Kobayashi: Long-term culture of Japanese human embryonic stem cells in feeder-free conditions. Cell Transplantation, 17(1-2): 27-33, 2008
• 41.Nalu Navarro-Alvarez, Jorge David Rivas-Carrillo, Alejandro Soto-Gutierrez, Takeshi Yuasa, Teru Okitsu, Hirofumi Noguchi, Shinichi Matsumoto, Jiro Takei, Noriaki Tanaka, Naoya Kobayashi：Reestablishment of microenvironment is necessary to maintain in vitro and in vivo human islet function. Cell Transplantation, 17(1-2): 111-119, 2008
• 42.Takeshi Nagasaka, Minoru Koi, Matthias Kloor, Johannes Gebert, Alex Vilkin, Naoshi Nishida, Sung Kwan Shin, Hiromi Sasamoto, Noriaki Tanaka, Nagahide Matsubara, C. Richard Boland, and Ajay Goel：Mutations in both KRAS and BRAF contribute to the methylator phenotype in colon cancer．Gastroenterology, 134: 1950-1960, 2008
• 43.Huang P, Watanabe M, Kaku H, Kashiwakura Y, Chen J, Saika T, Nasu Y, Fujiwara T, Urata Y, Kumon H：Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model. Cancer Gene Ther, 15: 315-322, 2008
• 44.Yokoyama T, Iwado E, Kondo Y, Aoki H, Hayashi Y, Georgescu M M, Sawaya R, Hess K R, Mills G B, Kawamura H, Hashimoto Y, Urata Y, Fujiwara T, Kondo S: Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells. Gene Ther, 15: 1233-1239, 2008
• 45.Kyo S, Takakura M, Fujiwara T, Inoue M：Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers. Cancer Sci, 99: 1528-1538, 2008
• 46.Ouchi M, Kawamura H, Urata Y, Fujiwara T：Antiviral activity of cidofovir against telomerase-specific replication-selective oncolytic adenovirus, OBP-301 (Telomelysin). Invest New Drug, 27(3): 241-245, 2008
• 47.Ikeda Y, Kojima T, Kuroda S, Endo Y, Sakai R, Hioki M, Kishimoto H, Uno F, Kagawa S, Watanabe Y, Hashimoto Y, Urata Y, Tanaka N, Fujiwara T：A novel antiangiogenic effect for telomeras-specific virotherapy through host immune system. J Immunol, 182(3): 1763-1769, 2008
• 48.Nakajima O, Matsunaga A, Ichimaru D, Urata Y, Fujiwara T, Kawakami K. Mol：Telomerase-specific virotherapy in animal model of human head and neck cancer. Mol Cancer Ther, 8(1): 171-177, 2008
• 49.Maida Y, Kyo S, Sakaguchi J, Mizumoto Y, Hashimoto M, Mori N, Ikoma T, Takakura M, Urata Y, Fujiwara T, Inoue M: Application of telomerase-specific replication-selective adenovirus to cytological diagnosis of gynecologic cancers．Int J Oncol, 34(6): 1549-1556, 2008
• 50.Wang ZG, Fukazawa T, Nishikawa T, Watanabe N, Sakurama K, Motoki T, Takaoka M, Hatakeyama S, Omori O, Ohara T, Tanabe S, Fujiwara Y, Shirakawa Y, Yamatsuji T, Tanaka N, Naomoto Y：TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells. Oncol Rep, 20(6): 1473-1477, 2008
• 51.Haugen AC, Goel A, Yamada K, Marra G, Nguyen TP, Nagasaka T, Kanazawa S, Koike J, Kikuchi Y, Zhong X, Arita M, Shibuya K, Oshimura M, Hemmi H, Boland CR, Koi M. Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer. Cancer Res, 68(20): 8465-8472, 2008
• 52.Arnold CN, Nagasaka T, Goel A, Scharf I, Grabowski P, Sosnowski A, Schmitt-Gräff A, Boland CR, Arnold R, Blum HE. Molecular characteristics and predictors of survival in patients with malignant neuroendocrine tumors. Int J Cancer, 123(7): 1556-1564, 2008
• 53.Nishida N, Nagasaka T, Nishimura T, Ikai I, Boland CR, Goel A. Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology. 47(3): 908-18, 2008

2007年

• 1.Rivas-Carrillo JD, Okitsu T, Tanaka N, Kobayashi N：Pancreas development and beta-cell differentiation of embryonic stem cells. Curr Med Chem, 14(14): 1573-1578, 2007
• 2.Totsugawa T, Yong C, Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Westerman KA, Kohara M, Reth M, Tanaka N, Leboulch P, Kobayashi N：Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination．J Hepatol, 47(1): 74-82, 2007
• 3.Soto-Gutierrez A, Navarro-Alvarez N, Zhao D, Rivas-Carrillo JD, Lebkowski J, Tanaka N, Fox IJ, Kobayashi N：Differentiation of mouse embryonic stem cells to hepatocyte-like cells by co-culture with human liver nonparenchymal cell lines．Nat Protoc, 2(2): 347-356, 2007
• 4.Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Chen Y, Yuasa T, Tanaka K, Narushima M, Miki A, Misawa H, Tabata Y, Jun HS, Matsumoto S, Fox IJ, Tanaka N, Kobayashi N：Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice．Diabetes, 56(5): 1259-1267, 2007
• 5.Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Tanaka K, Chen Y, Misawa H, Okitsu T, Noguchi H, Tanaka N, Kobayashi N：Construction and transplantation of an engineered hepatic tissue using a polyaminourethane-coated nonwoven polytetrafluoroethylene fabric．Transplantation, 83(2): 129-137, 2007
• 6.Shinoda M, Tilles AW, Kobayashi N, Wakabayashi G, Takayanagi A, Totsugawa T, Harada H, Obara H, Suganuma K, Berthiaume F, Shimazu M, Shimizu N, Tanaka N, Kitajima M, Tompkins RG, Toner M, Yarmush ML：A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats．J Surg Res, 137(1): 130-140, 2007
• 7.Nobuhisa T, Naomoto Y, Okawa T, Takaoka M, Gunduz M, Motoki T, Nagatsuka H, Tsujigiwa H, Shirakawa Y, Yamatsuji T, Haisa M, Matsuoka J, Kurebayashi J, Nakajima M, Taniguchi S, Sagara J, Dong J, Tanaka N：Translocation of heparanase into nucleus results in cell differentiation．Cancer Sci, 98(4): 535-540, 2007
• 8.Fukazawa T, Maeda Y, Durbin ML, Nakai T, Matsuoka J, Tanaka H, Naomoto Y, Tanaka N：Pulmonary adenocarcinoma-targeted gene therapy by a cancer- and tissue-specific promoter system．Mol Cancer Ther, 6(1): 244-252, 2007
• 9.Naomoto Y, Gunduz M, Takaoka M, Okawa T, Gunduz E, Nobuhisa T, Kobayashi M, Shirakawa Y, Yamatsuji T, Sonoda R, Matsuoka J, Tanaka N：Heparanase promotes angiogenesis through Cox-2 and HIF1alpha．Med Hypotheses, 68(1): 162-165, 2007
• 10.Teraishi F, Uno F, Kagawa S, Fujiwara T, Gouchi A, Tanaka N：Advanced gastric adenocarcinoma mimicking a submucosal tumor．Endoscopy, Suppl 1: E191-2, 2007
• 11.Sato Y, Fujiwara T, Mine T, Shomura H, Homma S, Maeda Y, Tokunaga N, Ikeda Y, Ishihara Y, Yamada A, Tanaka N, Itoh K, Harada M, Todo S：Immunological evaluation of personalized peptide vaccination in combination with a 5-fluorouracil derivative (TS-1) for advanced gastric or colorectal carcinoma patients．Cancer Sci, 98(7): 1113-1119, 2007
• 12.Kagawa S, Fujiwara T, Nishizaki M, Naomoto Y, Hiroshi I, Tanaka N：Adenomyoma of the stomach presenting as localized peritonitis．Dig Dis Sci, 52(11): 3184-3187, 2007
• 13.Fujiwara T, Urata Y, Tanaka N：Telomerase-specific oncolytic virotherapy for human cancer with the hTERT promoter. Curr Cancer Drug Targets, 7(2): 191-201, 2007
• 14.Fujiwara T, Naomoto Y, Motoki T, Shigemitsu K, Shirakawa Y, Yamatsuji T, Kataoka M, Haisa M, Fujiwara T, Egi M, Morimatsu H, Hanazaki M, Katayama H, Morita K, Mizumoto K, Asou T, Arima H, Sasaki H, Matsuura M, Gunduz M, Tanaka N：Effects of a novel palatinose based enteral formula (MHN-01) carbohydrate-adjusted fluid diet in improving the metabolism of carbohydrates and lipids in patients with esophageal cancer complicated by diabetes mellitus．J Surg Res, 138(2): 231-240, 2007
• 15.Matsumoto Y, Nagasaka T, Kambara T, Hoshizima N, Murakami J, Sasamoto H, Hosokawa M, Naomoto Y, Isozaki H, Shimizu K, Tanaka N, Matsubara N：Microsatellite instability and clinicopathological features in esophageal squamous cell cancer．Oncol Rep, 18(5): 1123-1127, 2007
• 16.Kimura, K, Nagasaka, T, Sasamoto, H, Notohara, K, Takeda, M, Komnami, K, Ishii, T, Tanaka, N, Matsubara, N：No duplicate KRAS mutation is identified on the same allele of gastric or colorectal cancer cells with multiple KRAS mutations. J Int Med Res, 35(4): 450-457, 2007
• 17.Murakami J, Lee YJ, Kokeguchi S, Tsujigiwa H, Asaumi J, Nagatsuka H, Fukui K, Kuroda M, Tanaka N, Matsubara N：Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines．Oncol Rep, 17(6): 1461-1467, 2007
• 18.Ishii T, Murakami J, Notohara K, Cullings HM, Sasamoto H, Kambara T, Shirakawa Y, Naomoto Y, Ouchida M, Shimizu K, Tanaka N, Jass JR, Matsubara N：Oesophageal squamous cell cancer may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa．Gut, 56: 13-19, 2007
• 19.Oyama T, Sadamori H, Matsukawa H, Murata H, Umeda Y, Watanabe Y, Ozaki M, Iwagaki H, Tanaka N, Yagi T：Small liver graft regenerates through immediate increase of HGF and IL-6--possible involvement of sinusoidal tensile/shear stress in small liver graft．Hepatogastroenterology, 54(79): 2078-2083, 2007
• 20.Takahashi HK, Iwagaki H, Hamano R, Wake H, Kanke T, Liu K, Yoshino T, Tanaka N, Nishibori M：Effects of adenosine on adhesion molecule expression and cytokine production in human PBMC depend on the receptor subtype activated．Br J Pharmacol, 150(6): 816-822, 2007
• 21.Umeda Y, Umeda Y, Yagi T, Sadamori H, Matsukawa H, Matsuda H, Shinoura S, Iwamoto T, Satoh D, Iwagaki H, Tanaka N：Preoperative proximal splenic artery embolization: a safe and efficacious portal decompression technique that improves the outcome of live donor liver transplantation．Transpl Int, 20(11): 947-955, 2007
• 22.Takahashi HK , Kanke T, Liu K, Yoshino T, Sendo T, Tanaka N, Nishibori M：Adenosine A2A-receptor stimulation inhibits lipopolysaccharide-induced interleukin-18 production in monocytes．J Pharmacol Sci, 104(2): 183-186, 2007
• 23.Takahashi HK, Iwagaki H, Yagi T, Kanke T, Liu K, Yoshino T, Tanaka N, Nishibori M：Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction．Clin Immunol, 123(3): 324-332, 2007
• 24.Takahashi HK, Iwagaki H, Hamano R, Kanke T, Liu K, Sadamori H, Yagi T, Yoshino T, Sendo T, Tanaka N, Nishibori M：Effect of adenosine receptor subtypes stimulation on mixed lymphocyte reaction．Eur J Pharmacol, 564(1-3): 204-210, 2007
• 25.Takahashi K, Kohno T, Matsumoto S, Nakanishi Y, Arai Y, Fujiwara T, Tanaka N, Yokota J：Clonality and heterogeneity of pulmonary blastoma from the viewpoint of genetic alterations: a case report．Lung Cancer, 57(1):103-108, 2007
• 26.Takaki A, Yagi T, Iwasaki Y, Sadamori H, Matsukawa H, Matsuda H, Shinoura S, Umeda Y, Miyake Y, Terada R, Kobashi H, Sakaguchi K, Tanaka N, Shiratori Y：Short-term high-dose followed by long-term low-dose hepatitis B immunoglobulin and lamivudine therapy prevented recurrent hepatitis B after liver transplantation．Transplantation, 83(2): 231-233, 2007
• 27.Takahashi HK, Iwagaki H, Hamano R, Kanke T, Liu K, Sadamori H, Yagi T, Yoshino T, Tanaka N, Nishibori M：The immunosuppressive effects of nicotine during human mixed lymphocyte reaction．Eur J Pharmacol, 559(1): 69-74, 2007
• 28.Takahashi K, Kohno T, Matsumoto S, Nakanishi Y, Arai Y, Yamamoto S, Fujiwara T, Tanaka N, Yokota J：Clonal and parallel evolution of primary lung cancers and their metastases revealed by molecular dissection of cancer cells．Clin Cancer Res, 13(1): 111-120, 2007
• 29.Kammori M, Poon SS, Nakamura K, Izumiyama N, Ishikawa N, Kobayashi M, Naomoto Y, Takubo K：Squamous cell carcinomas of the esophagus arise from a telomere-shortened epithelial field．Int J Mol Med, 20(6): 793-799, 2007
• 30.Osawa M, Takigawa N, Kiura K, Ichimura K, Matsuoka J, Hotta K, Tabata M, Tanimoto M：Isolated metastasis of lung cancer to the thyroid gland．Lung Cancer, 58(1): 156-158, 2007
• 31.Iguchi T, Matsuoka J, Sato S, Okumura Y, Omori M, Mifune H, Akaki S, Kanazawa S：F-18 FDG PET demonstration of a thyroid metastasis in a patient with colon cancer．Clin Nucl Med, 32(5): 361-362, 2007
• 32.Katase N, Nagatsuka H, Tsujigiwa H, Gunduz M, Tamamura R, Pwint HP, Rivera RS, Nakajima M, Naomoto Y, Nagai N：Analysis of the neoplastic nature and biological potential of sporadic and nevoid basal cell carcinoma syndrome-associated keratocystic odontogenic tumor．J Oral Pathol Med, 36(9): 550-554, 2007
• 33.Cengiz B, Gunduz M, Nagatsuka H, Beder L, Gunduz E, Tamamura R, Mahmut N, Fukushima K, Ali MA, Naomoto Y, Shimizu K, Nagai N：Fine deletion mapping of chromosome 2q21-37 shows three preferentially deleted regions in oral cancer．Oral Oncol, 43(3): 241-247, 2007
• 34.Oka Y, Miyazaki M, Takatsu S, Kunitomo K, Uno F, Maruyama M, Matsuda H：Sevelamer hydrochloride exacerbates metabolic acidosis in hemodialysis patients, depending on the dosage. Ther Apher Dial, 11(2): 107-113, 2007
• 35.Kato H, Honma R, Sanda T, Fujiwara T, Ito E, Yanagisawa Y, Imai J, Okamoto T, Watamabe S Biochem Bioph：Knock down of hSNF5/Ini1 causes cell-cycle arrest and apoptosis in a p53-dependent manner. Biochem Bioph Res Com, 361(3): 580-585, 2007
• 36.Sung Kwan Shin, Nagasaka　T, Barbara H. Jung, Matsubara N, Won Ho Kim, John M. Carethers, C. Richard Boland, Ajay Goel：Epigenetic and Genetic Alterations in Netrin-1 Receptors UNC5C and DCC in Human Colon Cancer. Gastroenterology, 133: 1849-1857, 2007
• 37.Shinagawa N, Fuchimoto S, Sueda T, Hiyama E, Takesue Y, Murakami Y, Ooge H, Uemura K, Mizuno I, Tsumura H, Hirata K, Katsuramaki T, Mizukuchi T, Ushijima Y, Ushida T, Aikawa N, Yo K, Takayama T, Sato T, Kato K, Yura J, Manabe T, Takeyama H, Wakasugi T, Taniguchi M, Yokoyama T, Takeuchi H, Yasui Y, Mashita K, Ikeda S, Yasunami Y, Ryu S, Ishikawa S, Mizuno A, Kubo S, Suehiro S, Fujimoto M, Higaki K, Tanimura H, Taniguchi K, Tsuji T, Ohnishi H, Yamaue H, Kawai M, Tanaka N, Iwagaki H, Kimura H：[Bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between april 2003 and march 2004．Jpn J Antibiot, 60(2): 59-97, 2007
• 38.Sadamori H，Yagi T, Matsukawa H, Matsuda H, Shinoura S, Umeda U, Iwamoto, T, Satoh D, Tanaka N：The outcome of living donor liver transplantation with prior spontaneous large portasystemic shunts. Transpl Int，21(2):156-62，2007
• 39.Nishida N，Nishimura T, Nagasaka T, Ikai I, Goel A, Boland CR：Extensive methylation is associated with beta-catenin mutations in hepatocellular carcinoma: evidence for two distinct pathways of human hepatocarcinogenesis．Cancer Res，67(10): 4586-4594，2007
• 40.Umeda Y, Yagi T, Sadamori H, Matsukawa H, Matsuda H, Shinoura S, Iwamoto T, Satoh D, Iwagaki H, Tanaka N：Preoperative proximal splenic artery embolization: a safe and efficacious portal decompression technique that improves the outcome of live donor liver transplantation. Transplant International, 20: 947-955, 2007
• 41.Noguchi H, Ueda M, Hayashi S, Kobayashi N, Nagata H, Iwanaga Y, Okitsu T,Matsumoto S：Comparison of M-Kyoto solution and histidine-tryptophan-ketoglutarate solution with a trypsin inhibitor for pancreas preservation in islet transplantation．Transplantation, 84(5): 655-658, 2007
• 42.Matsumoto S, Noguchi H, Naziruddin B, Onaca N, Jackson A, Nobuyo H, Okitsu T, Kobayashi N, Klintmalm G, Levy M：Improvement of pancreatic islet cell isolation for transplantation．Proc (Bayl Univ Med Cent), 20(4): 357-362, 2007
• 43.Noguchi H, Nakai Y, Ueda M, Masui Y, Futaki S, Kobayashi N, Hayashi S, Matsumoto S：Activation of c-Jun NH2-terminal kinase (JNK) pathway during islet transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitor．Diabetologia, 50(3): 612-619, 2007
• 44.Noguchi H, Ueda M, Matsumoto S, Kobayashi N, Hayashi S：BETA2/NeuroD protein transduction requires cell surface heparan sulfate proteoglycans．Hum Gene Ther, 18(1): 10-17, 2007
• 45.Parekkadan B, van Poll D, Megeed Z, Kobayashi N, Tilles AW, Berthiaume F, Yarmush ML：Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells．Biochem Biophys Res Commun, 363(2): 247-252, 2007
• 46.Navarro Alvarez Nalu, Alejandro Soto Gutierrez, Kobayashi N：Hepatocyte transplantation: a step forward．Curr Organ Transplant, 12: 652-658, 2007
• 47.Jorge David Rivas Carrillo, Okitsu T, Kobayashi N：Current cell-based approaches for the treatment of diabetes mellitus．Biotechnol Genet Eng Rev, 24: 281-95, 2007

2006年

2006年

• 1.Gotohda N, Nishimura M, Yoshida J, Nagai K and Tanaka N：The pattern of Lymphatic Metastases in Superficial Squamous Cell of the Esophagus．Hepato-Gastroenterology, 53(67): 115-119, 2006
• 2.Watanabe T, Hioki M, Fujiwara T, Nishizaki M, Kagawa S, Taki M, Kishimoto H, Endo Y, Urata Y, Tanaka N, Fujiwara T：Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells． Exp Cell Res, 312(3): 256-265, 2006
• 3.Naka K, H Dansako, N Kobayashi, M Ikeda, N Kato：Hepatitis C virus NS5B delays cell cycle progression by inducing interferon-β via Toll-like receptor 3 signaling pathway without replicating viral genomes．Virology, 346(2): 348-362, 2006
• 4.Wynter CV, Kambara T, Walsh MD, Leggett BA, Young J, Jass JR：DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients． Int J Cancer, 118: 907-915, 2006
• 5.Imada T, Matsuoka J, Nobuhisa T, Okawa T, Murata T, Tabuchi Y, Shirakawa Y, Ohara N, Gunduz M, Nagatsuka H, Umeoka T, Yamamoto Y, Nakajima M, Tanaka N, Naomoto Y：COX-2 induction by heparanase in the progression of breast cancer．Int J Mol Med, 17(2): 221-228, 2006
• 6.Shirakawa Y, Naomoto Y, Noma K, Sakurama K, Nishikawa T, Nobuhisa T, Kobayashi M, Okawa T, Asami S, Yamatsuji T, Haisa M, Matsuoka J, Hanazaki M, Morita K, Hiraki T, Tanaka N：Colonic interposition and supercharge for esophageal reconstruction．Langenbecks Arch Surg, 91(1): 19-23, 2006
• 7.Katsuno G, Takahashi HK, Iwagaki H, Mizuno K, Yagi T, Mori S, Saito S, Yoshino T, Nishibori M, Tanaka N： The immunosuppressive effects of ciprofloxacin during human mixed lymphocyte reaction．Clin Immunol, 119(1): 110-119, 2006
• 8.Tanaka K, Kobayashi N, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Narushima M, Miki A, Okitsu T, Noguchi H, Tanaka N：Prolonged survival of mice with acute liver failure with transplantation of monkey hepatocytes cultured with an antiapoptotic pentapeptide V5. Transplantation, 81(3): 427-437, 2006
• 9.Fujiwara T, Kagawa S, Kishimoto H, Endo Y, Hioki M, Ikeda Y, Sakai R, Urata Y, Tanaka N, Fujiwara T： Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel: Preclinical evaluation of chemovirotherapy．Int J Cancer, 119: 432-440, 2006
• 10.Matsuda H, Yagi T, Sadamori H, Matsukawa H, Shinoura S, Murata H, Umeda Y, Tanaka N：Complications of arterial reconstruction in living donor liver transplantation: a single-center experience．Surg Today, 36(3): 245-251, 2006
• 11.Fujiwara T, Tanaka N, Kanazawa S, Ohtani S, Saijo Y, Nukiwa T, Yoshimura K, Sato T, Eto Y, Chada S, Nakamura H, Kato H：Multicenter phase I study of repeated intratumoral delivery of adenoviral p53in patients with advanced non-small-cell lung cancer．J Clin Oncol, 24(11): 1689-1699, 2006
• 12.Katsuno G, Takahashi HK, Iwagaki H, Sugita S, Mori S, Saito S, Yoshino T, Nishibori M, Tanaka N：The effect of ciprofloxacin on CD14 and toll-like receptor-4 expression on human monocytes. Shock, 25(3): 247-253, 2006
• 13.Fujiwara T, Naomoto Y, Yamatsuji T, Shirakawa Y, Noguchi H, Fujiwara T, Oohara N, Gunduz M, Nagatsuka H, Nishie M, Uetsuka H, Hamazaki S, Tanaka N：Three Cases of Adenocarcinoma Arising in Extremely Long-Segment Barrett's Esophagus．Dig Dis Sci, 51(3): 533-538, 2006
• 14.Takahashi K, Kohno T, Ajima R, Sasaki H, John D. MINNA, Fujiwara T, Tanaka N, Yokota J：Homozygous deletion and reduces expression of the DOCK8 gene in human lung cancer．International Journal Oncology, 28: 321-328, 2006
• 15.Ikeda H , Kobayashi N, Tanaka Y, Nakaji S, Yong C, Okitsu T, Oshita M, Matsumoto S, Noguchi H, Narushima M, Tanaka K, Miki A, Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Tanaka K, Jun HS, Tanaka N, Yoon JW：A newly developed bioartificial pancreas successfully controls blood glucose in totally pancreatectomized diabetic pigs．Tissue Eng, 12(7): 1799-1809, 2006
• 16.Kobayashi M, Naomoto Y, Nobuhisa T, Okawa T, Takaoka M, Shirakawa Y, Yamatsuji T, Matsuoka J, Mizushima T, Matsuura H, Nakajima M, Nakagawa H, Rustgi A, Tanaka N：Heparanase regulates esophageal keratinocyte differentiation through nuclear translocation and heparan sulfate cleavage．Differentiation, 74(5): 235-43, 2006
• 17.Kishimoto H, Kojima T, Watanabe Y, Kagawa S, Fujiwara T, Uno F, Teraishi F, Kyo S, Mizuguchi H, Hashimoto Y, Urata Y, Tanaka N, Fujiwara T：In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus．Nat Med, 1213-1219, 2006
• 18.Hamano R, Takahashi HK, Iwagaki H, Yoshino T, Nishibori M, Tanaka N：STIMULATION OF alpha7 NICOTINIC ACETYLCHOLINE RECEPTOR INHIBITS CD14 AND THE TOLL-LIKE RECEPTOR 4 EXPRESSION IN HUMAN MONOCYTES．Shock, 358-364, 2006
• 19.Takahashi HK, Iwagaki H, Hamano R, Yoshino T, Tanaka N, Nishibori M：Effect of nicotine on IL-18-initiated immune response in human monocytes．J Leukoc Biol, 80(6): 1388-1394, 2006
• 20.Takahashi HK, Iwagaki H, Hamano R, Yoshino T, Tanaka N, Nishibori M：alpha7 Nicotinic Acetylcholine Receptor Stimulation Inhibits Lipopolysaccharide-Induced Interleukin-18 and -12 Production in Monocytes．J Pharmacol Sci, 102(1): 143-146, 2006
• 21.Fukazawa T, Matsuoka J, Naomoto Y, Nakai T, Durbin ML, Kojima I, Lakey JR, Tanaka N：Development of a novel beta-cell specific promoter system for the identification of insulin-producing cells in vitro cell cultures． Exp Cell Res, 312(17): 3404-3412, 2006
• 22.Soto-Gutierrez A, Kobayashi N, Rivas-Carrillo JD, Navarro-Alvarez N, Zhao D, Okitsu T, Noguchi H, Basma H, Tabata Y, Chen Y, Tanaka K, Narushima M, Miki A, Ueda T, Jun HS, Yoon JW, Lebkowski J, Tanaka N, Fox IJ：Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes．Nat Biotechnol, 24(11): 1412-1419, 2006
• 23.Miyaso H, Morimoto Y, Ozaki M, Haga S, Shinoura S, Choda Y, Murata H, Katsuno G, Huda K, Takahashi H, Tanaka N, Iwagaki H：Protective effects of nafamostat mesilate on liver injury induced by lipopolysaccharide in rats: possible involvement of CD14 and TLR-4 downregulation on Kupffer cells．DIGESTIVE DISEASES AND SCIENCES, 51(11): 2007-2012, 2006
• 24.Nagasaka T, Goel A, Matsubara N, Tanaka N：Detection of fecal DNA methylation for colorectal neoplasia: does it lead to an optimal screening test? Acta Med Okayama, 249-256, 2006
• 25.Ohtawa Y, Naomoto Y, Shirakawa Y, Takaoka M, Murata T, Sonoda R, Sakurama K, Yamatsuji T, Gunduz M, Tsujigiwa H, Nagatsuka H, Terada N, Itano S, Horiki S, Yanagihara K, Nakajima M, Tanaka N：The close relationship between heparanase and cyclooxygenase-2 expressions in signet-ring cell carcinoma of the stomach．Hum Pathol, 37(9): 1145-1152, 2006
• 26.Ozaki K, Nagasaka T, Notohara K, Kambara T, Takeda M, Sasamoto H, Jass JR, Tanaka N, Matsubara N：Heterogeneous microsatellite instability observed within epithelium of ulcerative colitis．Int J Cancer, 119(11): 2513-2519, 2006
• 27.Teraishi F, Fujiwara T, Jikuhara A, Kamitani S, Morino Y, Sato K, Tanaka N：Esophageal intramural pseudodiverticulosis with esophageal strictures successfully treated with dilation therapy．Ann Thorac Surg, 82(3): 1119-1121, 2006
• 28.Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Chen Y, Yamatsuji T, Tanaka N, Kobayashi N：Differentiation of human embryonic stem cells to hepatocytes using deleted variant of HGF and poly-amino-urethane-coated nonwoven polytetrafluoroethylene fabric．Cell Transplant, 15(4): 335-341, 2006
• 29.Miki A, Narushima M, Okitsu T, Takeno Y, Soto-Gutierrez A, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Tanaka K, Noguchi H, Matsumoto S, Kohara M, Lakey JR, Kobayashi E, Tanaka N, Kobayashi N：Maintenance of mouse, rat, and pig pancreatic islet functions by coculture with human islet-derived fibroblasts．Cell Transplant, 15(4): 325-334, 2006
• 30.Hiraki T, Gobara H, Takemoto M, Mimura H, Mukai T, Himei K, Hase S, Iguchi T, Fujiwara H, Yagi T, Tanaka N, Kanazawa S：Percutaneous radiofrequency ablation combined with previous bronchial arterial chemoembolization and followed by radiation therapy for pulmonary metastasis from hepatocellular carcinoma．J Vasc Interv Radiol, 17(7): 1189-1193, 2006
• 31.Takahashi HK, Watanabe T, Yokoyama A, Iwagaki H, Yoshino T, Tanaka N, Nishibori M：Cimetidine induces interleukin-18 production through H2-agonist activity in monocytes．Mol Pharmacol, 70(2): 450-453, 2006
• 32.Noguchi H, Matsumoto S, Matsushita M, Kobayashi N, Tanaka K, Matsui H, Tanaka N：Immunosuppression for islet transplantation．Acta Med Okayama, 60(2): 71-76, 2006
• 33.Yamatsuji T, Naomoto Y, Shirakawa Y, Gunduz M, Hiraki T, Yasui K, Kawata M, Hanazaki M, Morita K, Sano S, Tanaka N, Kanazawa S：Intra-aortic stent graft in oesophageal carcinoma invading the aorta. Prophylaxis for fatal haemorrhage．Int J Clin Pract, 60(12): 1600-1603, 2006
• 34.Huda KA, Guo L, Haga S, Murata H, Ogino T, Fukai M, Yagi T, Iwagaki H, Tanaka N, Ozaki M：Ex vivo adenoviral gene transfer of constitutively activated STAT3 reduces post-transplant liver injury and promotes regeneration in a 20% rat partial liver transplant model．Transpl Int, 19(5): 415-423, 2006
• 35.Fujiwara T, Naomoto Y, Yamatsuji T, Shirakawa Y, Noguchi H, Fujiwara T, Oohara N, Gunduz M, Nagatsuka H, Nishie M, Uetsuka H, Hamazaki S, Tanaka N：Three cases of adenocarcinoma arising in extremely long-segment Barrett's esophagus．Dig Dis Sci, 51(3): 533-538, 2006
• 36.Maeda Y, Hwang-Verslues WW, Wei G, Fukazawa T, Durbin ML, Owen LB, Liu X, Sladek FM：Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene．Biochem J, 400(2): 303-313, 2006
• 37.Hui-Ying Qiu, Fujimori Y, Nishioka K, Yamaguchi N, Hashimoto-Tamaoki T, Sugihara A, Terada N, Nagaya N, Kanda M, Kobayashi N, Tanaka N, A Westerman Karen, Philippe Leboulch, Hara H：Postnatal neovascularization by endothelial progenitor cells immortalized with the simian virus 40T antigen gene．Int J Oncol , 28(4): 815-821, 2006
• 38.Matsumoto S, Noguchi H,Yonekawa Y, Okitsu T, Iwanaga Y, Xiaoling Liu, Nagata H, Kobayashi N, Camillo Ricordi：Pancreatic islet transplantation for treating diabetes．Expert Opin Biol Ther, 6(1): 23-37, 2006, 2006
• 39.Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Okitsu T, Chen Y, Tabata Y, Misawa H, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N：Amelioration of diabetes in mice after single-donor islet transplantation using the controlled release of gelatinized FGF-2．Cell Transplant, 15(10): 939-944, 2006
• 40.Navarro-Alvarez N, Soto-Gutierrez A, Rivas-Carrillo JD, Chen Y, Yamamoto T, Yuasa T, Misawa H, Takei J, Tanaka N, Kobayashi N：Self-assembling peptide nanofiber as a novel culture system for isolated porcine hepatocytes．Cell Transplant, 15(10): 921-927, 2006
• 41.Misawa H, Kobayashi N, Soto-Gutierrez A, Chen Y, Yoshida A, Rivas-Carrillo JD, Navarro-Alvarez N, Tanaka K, Miki A, Takei J, Ueda T, Tanaka M, Endo H, Tanaka N, Ozaki T：PuraMatrix facilitates bone regeneration in bone defects of calvaria in mice．Cell Transplant, 15(10): 903-910, 2006
• 42.Miki A, Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Chen Y, Tanaka K, Narushima M, Tabata Y, Okitsu T, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N：Maintenance of neovascularization at the implantation site of an artificial device by bFGF and endothelial cell transplant．Cell Transplant, 15(10): 893-901, 2006
• 43.Chen Y, Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Yamatsuji T, Shirakawa Y, Tanaka N, Kobayashi N：Instant hepatic differentiation of human embryonic stem cells using activin A and a deleted variant of HGF．Cell Transplant, 15(10): 865-871, 2006
• 44.Tanaka K, Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Jun HS, Kobayashi N：Functional hepatocyte culture and its application to cell therapies．Cell Transplant, 15(10): 855-864, 2006
• 45.Teraishi F, Uno F, Kagawa S, Gochi A, Fujiwara T, Tanaka N：A case report--The marked response to gemcitabine combined with irinotecan and low-dose cisplatin chemotherapy for advanced gastric cancer with multiple liver metastases．Gan To Kagaku Ryoho, 33(12): 1885-1887, 2006
• 46.Hideo Kohka Takahashi 1, Hiromi Iwagaki 2, Ryosuke Hamano 2, Tadashi Yoshino 3, Noriaki Tanaka 2, Masahiro Nishibori 1, Departments of 1 Pharmacology, 2 Gastroenterological Surgery, and 3 Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science: Nicotinic Acetyicholine Receptor Stimulation Inhibits Lipopolysaccharide-Induced Interleukin-18 and -12 Production in Monocytes．Journal of Pharmacological Sciences, 102(1) : 143-146, 2006
• 47.Sadamoti H, Yagi T, Matsukawa H, Matsuda H, Shinoura S, Umeda Y, Narushima M, Tanaka N：Successful Re-transection of Conglutinated Hepatic Resection Plane for Repeate Systematized Hepatectomy．Hepatogastroenterology, 2006
• 48.Kagawa S, Fujiwara T, Tokunaga N, Nishizaki M, Uno F, Teraishi F, Gouchi A, Matsuoka J, Tanaka N：A case of advanced gastric cancer with liver metastasis completely responding to CPT-11+low-dose 5-FU+CDDP chemotherapy．Gan To Kagaku Ryoho, 33(9): 1317-1320, 2006

2005年

• 1.Nobuhisa T, Naomoto Y, Ohkawa T, Takaoka M, Ono R, Murata T, Gunduz M, Shirakawa Y, Yamatsuji T, Haisa M, Matsuoka J, Tsujigiwa H, Nagatsuka H, Nakajima M, Tanaka N：Heparanase expression correlates with malignant potential in human colon cancer．Journal Cancer Research Clinical Oncology，131(4): 229-237，2005
• 2.Shima Y, Yagi T, Inagaki M, Sadamori H, Tanaka N, Horimi T, Hamazaki S：Intraductal oncocytic papillary neoplasm of the pancreas with celiac artery compression syndrome and a jejunal artery aneurysm: report of a case．Surgery Today，35(1): 86-90，2005
• 3.Takahashi HK, Mori S, Iwagaki H, Yoshino T, Tanaka N, Weitz-Schmidt G, Nishibori M：Differential effect of LFA703, pravastatin, and fluvastatin on production of IL-18 and expression of ICAM-1 and CD40 in human monocytes．J Leukoc Biol，77(3): 400-407，2005
• 4.Takahashi HK, Iwagaki H, Tamura R, Katsuno G, Xue D, Sugita S, Mori S, Yoshino T, Tanaka N, Nishibori M：alpha1-Adrenergic Receptor Antagonists Induce Production of IL-18 and Expression of ICAM-1 and CD40 in Human Monocytes．J Immunother，28(1): 40-43，2005
• 5.Sun DS, H Iwagaki, M Ozaki, T Ogino, S Kusaka, Y Fujimoto, H Murata, H Sadamori, H Matsukawa, N Tanaka, T Yagi：Prolonged survival of donor-specific rat intestinal allograft by intraportal administration of bone-marrow-derived immature dendritic cells. Transplant Immunology，14: 17-20，2005
• 6.Murakami T, Iwagaki H, Saito S, Ohtani S, Kuroki K, Kuinose M, Tanaka N and Tanemoto K：Equivalence of the Acute Ctokine Surge and Myocardial Injury after Coronary Artery Bypass Grafting With and Without a Novel Extracorporeal Circulation System．The Journal of International Medical Research，33: 133-149，2005
• 7.Nakajo T, Yamatsuji T, Ban H, Shigemitsu K, Haisa M, Motoki T, Noma K, nobuhisa T, Matsuoka J, Gunduz M, Yonezawa K, Tanaka N, Naomoto Y：Glutamine is a key regulator for amino acid-controlled cell growth though the mTOR signaling pathway in rat intestinal epithelial cells．Biochemical and Biophysical Research Communications，326(1): 174-180，2005
• 8.Tokunaga N, Murakami T, Endo Y, Nishizaki M, Kagawa S, Tanaka N and Fujiwara T：human Monocyte-Derived Dendritic Cells Pulsed with Wild-Type p53 Protein Efficiently Induce CTLs against p53 Overexpressing Human Cancer Cells．Clinical Cancer Research，11: 1312-1318，2005
• 9.Kimura N, Nagasaka T, Murakami J, Sasamoto H, Murakami M, Tanaka N, Matsubara N：Methylatio profiles of genes utilizing newly developed CpG island methylation microarray on colorectal cancer patients．Nucleic Acids Res, 33(5): e46，2005
• 10.Takahashi HK, Xue D, Iwagaki H, Tamura R, Katsuno G, Yagi T, Yoshino T, Mori S, Nishibori M, Tanaka N：Prostaglandin E1-initiated immune regulation during human mixed lymphocyte reaction．Clin Immunol，115(1): 85-92，2005
• 11.Nobuhisa T, Naomoto Y, Takaoka M, Tabuchi Y, Ookawa K, Kitamoto D, Gunduz E, Gunduz M, Nagatsuka H, Haisa M, Matsuoka J, Nakajima M, Tanaka N：Emergence of nuclear heparanase induces differentiation of human mammary cancer cells．Biochem Biophys Res Commun, 31(1): 175-180，2005
• 12.Takahashi HK, Iwagaki H, Tamura R, Katsuno G, Xue D, Sugita S, Mori S, Yoshino T, Tanaka N, Nishibori M：Differential effect of prostaglandins E1 and E2 on lipopolysaccharide-induced adhesion molecule expression on human monocytes．Eur J Pharmacol，512(2-3): 223-230，2005
• 13.Kobayashi N, Rivas-Carrillo JD, Soto-Gutierrez A, Fukazawa T, Chen Y, Navarro-Alvarez N, Tanaka N：Gene delivery to embryonic stem cells．Birth Defects Res C Embryo Today，75(1): 10-8, 2005
• 14.Murakami J, Asaumi J, Kawai N, Tsujigiwa H, Yanagi Y, Nagatsuka H, Inoue T, Kokeguchi S, Kawasaki S, Kuroda M, Tanaka N, Matsubara N, Kishi K：Effects of histone deacetylase inhibitor FR901228 on the expression level of telomerase reverse transcriptase in oral cancer．Cancer Chemother Pharmacol，56(1): 22-28，2005
• 15.Takahashi HK, Iwagaki H, Tamura R, Yagi T, Yoshino T, Mori S, Tanaka N, Nishibori M：Effect of antibodies against intercellular adhesion molecule-1, B7, and CD40 on interleukin-18-treated human mixed lymphocyte reaction．J Pharmacol Sci，97(3): 447-450，2005
• 16.Taki M, Kagawa S, Nishizaki M, Mizuguchi H, Hayakawa T, Kyo S, Nagai K, Urata Y, Tanaka N, Fujiwara T：Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 ('Telomelysin-RGD')．Oncogene，24(19):3130-3140，2005
• 17.Joanne young, Melissa A. Barker, Lisa A Simms, Michal D. Walsh, Kelli G. Biden, Daniel Buchanan, Ron Buttenshaw, Vicki J. Whitehall, Sven Arnold, Leigh Jackson, Kambara T, Kevin J. Spring, mark A. Jenkins, Graeme J Walker, John L. Hopper, Barbara A. Leggett and Jeremy R. Jass：Evidence for BRAF Mutation and Variable Levels of Microsatellite Instability in an Syndrome of Familial Colorectal Cancer．CLINICAL GASTROENTETROLOGY AND HEPATOLOGY，3: 254-263，2005
• 18.Fujimoto Y, Iwagaki H, Ozaki M, Ogino T, Murata H, Sun DS, Sadamori H, Takahashi HK, Tanaka N, Yagi T：Involvement of prostaglandin receptors (EPR2-4) in in vivo immunosuppression of PGE2 in rat skin transplant model．INTERNATIONAL IMMUNOPHARMACOLOGY，5(7-8): 1131-1139，2005
• 19.Narushima M, Kobayashi N, Okitsu T, Tanaka Y, Li SA, Chen Y, Miki A, Tanaka K, Nakaji S, Takei K, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Jun HS, Westerman KA, Noguchi H, Lakey JR, Leboulch P, Tanaka N, Yoon JW：A human beta-cell line for transplantation therapy to control type 1 diabetes．Nat Biotechnol，23(10): 1274-1282，2005
• 20.Morishita N, Nakagami H, Morishita R, Takeda S, Mishima F, Terazono B, Nishijima S, Kaneda Y, Tanaka N：Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector．Biochem Biophys Res Commun，334(4): 1121-1126，2005
• 21.Yoshii M, Jikuhara A, Mori S, Iwagaki H, Takahashi HK, Nishibori M, Tanaka N：Mast cell tryptase stimulates DLD-1 carcinoma through prostaglandin- and MAP kinase-dependent manners．J Pharmacol Sci，98(4): 450-458，2005
• 22.Katsuno G, Takahashi HK, Iwagaki H, Mizuno K, Mori S, Yoshino T, Nishibori M, Tanaka N：Nafamostat mesilate induces production of interleukin-12 and -18 in human peripheral blood mononuclear cells. J Pharmacol Sci，98(4): 463-466，2005
• 23.Noma K, Naomoto Y, Gunduz M, Matsuoka J, Yamatsuji T, Shirakawa Y, Nobuhisa T, Okawa T, Takaoka M, Tomono Y, Hiroyuki O, Gunduz E, Tanaka N：Effects of imatinib vary with the types of KIT-mutation in gastrointestinal stromal tumor cell lines．Oncol Rep，14(3):645-650，2005
• 24.Takahashi HK, Iwagaki H, Xue D, Katsuno G, Sugita S, Mizuno K, Mori S, Saito S, Yoshino T, Tanaka N, Nishibori M：Effect of ciprofloxacin-induced prostaglandin E2 on interleukin-18-treated monocytes. Antimicrob Agents Chemother，49(8): 3228-3233，2005
• 25.Maki Y, Murakami J, Asaumi J, Tsujigiwa H, Nagatsuka H, Kokeguchi S, Fukui K, Kawai N, Yanagi Y, Kuroda M, Tanaka N, Matsubara N, Kishi K：Role of O(6)-methylguanine-DNA methyltransferase and effect of O(6)-benzylguanine on the anti-tumor activity of cis-diaminedichloroplatinum(II) in oral cancer cell lines．Oral Oncol. 41(10): 984-993，2005
• 26.Teraishi F, Kagawa S, Watanabe T, Tango Y, Kawashima T, Umeoka T, Nisizaki M, Tanaka N, Fujiwara T： ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma．FEBS Lett. 579(19): 4069-4075，2005
• 27.Naomoto Y, Yamatsuji T, Shigemitsu K, Ban H, Nakajo T, Shirakawa Y, Motok T, Kobayashi M, Gunduz M, Tanaka N：Rational role of amino acids in intestinal epithelial cells (Review). Int J Mol Med. 16(2): 201-204. 2005
• 28.Mizuno K, Takahashi HK, Iwagaki H, Katsuno G, Kamurul HA, Ohtani S, Mori S, Yoshino T, Nishibori M, Tanaka N：Beta2-adrenergic receptor stimulation inhibits LPS-induced IL-18 and IL-12 production in monocytes．Immunol Lett，101(2): 168-172，2005
• 29.Takahashi HK, Iwagaki H, Mori S, Yoshino T, Tanaka N, Nishibori M：Prostaglandins E1 and E2 inhibit lipopolysaccharide-induced interleukin-18 production in monocytes．Eur J Pharmacol，517(3): 252-256，2005
• 30.Naomoto Y, Takaoka M, Okawa T, Nobuhisa T, Gunduz M, Tanaka N：The role of heparanase in gastrointestinal cancer (Review)．Oncol Rep. 14(1): 3-8，2005
• 31.Hamanaka S, Tanemoto K, Inagaki E, Yamasawa T, Yoshida K, Mochizuki S, Goto M, Miyasaka T, Kajiya F, Tanaka N：Direct measurement of nitric oxide during experimental cardiopulmonary bypass．J Int Med Res，33(3): 295-300，2005
• 32.Takahashi HK, Mori S, Iwagaki H, Yoshino T, Tanaka N, Nishibori M：Simvastatin induces interleukin-18 production in human peripheral blood mononuclear cells．Clin Immunol，116(3): 211-216，2005
• 33.Chen Y, Kobayashi N, Suzuki S, Soto-Gutierrez A, Rivas-Carrillo JD, Tanaka K, Navarro-Alvarez N, Fukazawa T, Narushima M, Miki A, Okitsu T, Amemiya H, Tanaka N：Transplantation of human hepatocytes cultured with deleted variant of hepatocyte growth factor prolongs the survival of mice with acute liver failure．Transplantation，79(10): 1378-1385，2005
• 34.Shiratori Y, Ito Y, Yokosuka O, Imazeki F, Nakata R, Tanaka N, Arakawa Y, Hashimoto E, Hirota K, Yoshida H, Ohashi Y, Omata M：Tokyo-Chiba Hepatitis Research Group：Antiviral therapy for cirrhotic hepatitis C: association with reduced hepatocellular carcinoma development and improved survival．Ann Intern Med. 142(2): 105-114，2005
• 35.Miyaso H, Morimoto Y, Ozaki M, Haga S, Shinoura S, Choda Y, Iwagaki H, Tanaka N：Obstructive jaundice increases sensitivity to lipopolysaccharide via TLR4 upregulation: Possible involvement in gut-derived hepatocyte growth factor-protection of hepatocytes. J Gastroenterol Hepatol，20(12): 1859-1866，2005
• 36.Okawa T, Naomoto Y, Nobuhisa T, Takaoka M, Motoki T, Shirakawa Y, Yamatsuji T, Inoue H, Ouchida M, Gunduz M, Nakajima M, Tanaka N：Heparanase is involved in angiogenesis in esophageal cancer through induction of cyclooxygenase-2．Clin Cancer Res. 11(22): 7995-8005，2005
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